HPE ProLiant DL380 Gen11 Drives

Upgrade your HPE ProLiant DL380 Gen11 server with genuine hot-plug drives. This versatile 2U platform supports 2.5-inch (SFF), 3.5-inch (LFF), and EDSFF (E3.S) drives across SAS, SATA, and NVMe interfaces — and every drive we sell is guaranteed compatible with your DL380 Gen11.

DL380 Gen11 Drive Specifications

• Form factors & bays: 2.5-inch SFF (up to 30 hot-plug bays), 3.5-inch LFF (up to 16 bays), and E3.S EDSFF NVMe (up to 36 bays), depending on chassis and drive cages.
• Interfaces & types: SAS (24G, backward-compatible to 12G), SATA (6G), and NVMe (U.3 and E3.S, PCIe Gen5) — available as both hard drives (HDD) and solid-state drives (SSD).
• Capacities: SSDs from 240GB up to 15.36TB; HDDs up to 2.4TB (SFF) or 26TB (LFF).
• Carriers: HPE Gen11 SFF Basic Carrier (BC) for SAS/SATA/U.3 NVMe, LFF low-profile carrier for SAS/SATA, and EDSFF carrier for E3.S NVMe.
• Boot & RAID: optional NS204i-u boot device (two M.2 NVMe SSDs in RAID 1), embedded Intel® VROC, and HPE MR-series Smart Array / TriMode controllers.

Before you order, match the drive to your chassis and backplane. The DL380 Gen11 ships in SFF, LFF, and EDSFF chassis with different backplanes, so confirm three things: the form factor (2.5-inch SFF, 3.5-inch LFF, or E3.S EDSFF), the interface your backplane supports (SAS, SATA, or NVMe), and the correct Gen11 carrier. TriMode (U.3) backplanes accept SAS, SATA, or NVMe in the same bay, but standard SAS/SATA backplanes will not accept NVMe drives.

Drive Form Factors, Interfaces & Carriers

The DL380 Gen11 supports three storage form factors. SFF (2.5-inch) is the most flexible, scaling to 24 front bays plus mid-tray and rear cages (up to 30 drives within HPE's thermal limits) and accepting SAS, SATA, or U.3 NVMe. LFF (3.5-inch) maximizes raw capacity with up to 12 front and 4 rear bays for high-capacity SAS/SATA HDDs. EDSFF (E3.S) is an all-NVMe option scaling to 36 PCIe Gen5 bays for the highest flash performance and density.

On TriMode (U.3) backplanes, a single bay can take a SAS, SATA, or NVMe drive, giving you room to mix media as needs change. SFF drives use HPE's Gen11 Basic Carrier (BC) — distinct from the Smart Carrier used on Gen10 and Gen10 Plus servers — so confirm your drives ship in the correct Gen11 carrier for proper fit, hot-plug operation, and status-LED function. For the full drive cage, backplane, and capacity matrix, see the official HPE QuickSpecs:

HPE ProLiant DL380 Gen11 QuickSpecs (PDF)

DL380 Gen11 Drive FAQ

What drives are compatible with the HPE DL380 Gen11?
Hot-plug SAS, SATA, and NVMe drives in 2.5-inch SFF, 3.5-inch LFF, or E3.S EDSFF form factors, as both HDDs and SSDs. The drive's form factor and interface must match your installed chassis and backplane, and SFF drives should use the Gen11 Basic Carrier.

How many drives does the DL380 Gen11 support?
Up to 30 SFF (2.5-inch) drives, up to 16 LFF (3.5-inch) drives, or up to 36 E3.S EDSFF NVMe drives, depending on the chassis and the front, mid-tray, and rear drive cages installed.

Does the DL380 Gen11 support NVMe SSDs?
Yes. It supports U.3 NVMe in 2.5-inch bays (on TriMode/U.3 backplanes) and E3.S EDSFF NVMe, both running over PCIe Gen5. NVMe requires an NVMe-capable backplane; a standard SAS/SATA backplane will not accept NVMe drives.

What carrier do DL380 Gen11 drives use?
2.5-inch drives use HPE's Gen11 Basic Carrier (BC), which differs from the Smart Carrier used on Gen10 and Gen10 Plus servers. Be sure any drive you buy ships in the correct Gen11 carrier so it seats properly and reports drive status correctly.

✅ Need help finding the right DL380 Gen11 drive? Browse our full selection above, or contact our HPE specialists for a guaranteed-compatible recommendation.

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