HPE 2.5-inch U.3 NVMe SSDs

2.5-inch U.3 NVMeSSDs

2.5-inch U.3 NVMe SSDs for HPE ProLiant servers. Most sit on the Basic Carrier (BC), for the tri-mode bays of Gen10 Plus, Gen11 and Gen12 servers, where one controller runs SAS, SATA and U.3 NVMe drives in the same bays; some sit on the SC or SCN carrier, for Gen10 models and for the DL325 Gen10 Plus and DL385 Gen10 Plus (v1). Our guide U.2 vs U.3 SSD explains how the two connectors differ.

  • 115 SSDs
  • NVMe Gen4
  • New and refurbished
  • Tested or factory sealed

Carriers, classes and generations from the HPE Solid State Disk Drives QuickSpecs a00001288enw, version 78 (November 2, 2026), and from the QuickSpecs of each server.

All 115 2.5-inch U.3 NVMe SSDs

Grouped by capacity; within each group, the drives in stock come first, ordered by how often our customers order them. Filter by interface, carrier, capacity, class and condition.

U.2 and U.3 NVMe SSDs compared

What to checkU.2 NVMeU.3 NVMe This page
CarrierMost on the Smart Carrier NVMe (SCN); some on the Basic Carrier (BC)Most on the Basic Carrier (BC); some on the SC or SCN carrier
BayAn NVMe bay: an NVMe cage or express bayA tri-mode bay, where one controller runs SAS, SATA and U.3 NVMe drives; or an NVMe bay
ServersGen9 to Gen10 Plus ProLiant models that HPE lists them forGen10 to Gen12 ProLiant models that HPE lists them for
InterfaceNVMe Gen3 and Gen4NVMe Gen4
Our pageU.2 NVMe SSDsU.3 NVMe SSDs

2.5-inch U.3 NVMe SSDs questions

What is the difference between U.3 and U.2?

Both are 2.5-inch NVMe drives. Most U.3 drives sit on the Basic Carrier (BC), from Gen10 Plus, where a tri-mode controller runs SAS, SATA and U.3 NVMe drives in the same bays. Most U.2 drives sit on the Smart Carrier NVMe (SCN), for the NVMe bays of Gen9 and Gen10 servers. The table below compares them.

Will a U.3 drive work in a SAS or SATA bay?

Only in a tri-mode bay: a U.3 drive needs a U.3 bay behind a tri-mode controller, or an NVMe bay. A bay wired for SAS and SATA only does not run it. Your server's drives page shows which bays it has.

Which servers take U.3 SSDs?

HPE lists 2.5-inch U.3 NVMe SSDs for 33 of the ProLiant servers we cover, from Gen10 to Gen12. Gen12: DL320 Gen12, DL325 Gen12, DL340 Gen12, DL345 Gen12, DL360 Gen12, DL380 Gen12, DL380a Gen12, DL580 Gen12, ML350 Gen12; Gen11: DL20 Gen11, DL320 Gen11, DL325 Gen11, DL345 Gen11, DL360 Gen11, DL365 Gen11, DL385 Gen11, DL560 Gen11, ML350 Gen11; Gen10 Plus: DL325 Gen10 Plus, DL325 Gen10 Plus v2, DL345 Gen10 Plus, DL360 Gen10 Plus, DL365 Gen10 Plus, DL380 Gen10 Plus, DL385 Gen10 Plus, DL385 Gen10 Plus v2; Gen10: BL460c Gen10, DL325 Gen10, DL380 Gen10, DL385 Gen10, DL560 Gen10, DL580 Gen10, ML350 Gen10. Each link opens that server's drives page, with HPE's list for it.

Servers HPE lists 2.5-inch U.3 NVMe SSDs for

From each server's HPE QuickSpecs. Each page lists the drives HPE lists for that server.

All drives by server · All HPE parts by server model

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