HPE ProLiant DL380 Gen10 Parts

HPE ProLiant DL380 Gen10 Parts

HPE ProLiant DL380 Gen10 Parts

The HPE ProLiant DL380 Gen10 is one of the most widely deployed 2U servers ever built — two sockets of 1st or 2nd Generation Intel Xeon Scalable compute, 24 slots of DDR4, Smart Array storage, and chassis options from 8SFF to 24SFF and 12LFF. Every part below is genuine HPE, available new and refurbished, and tested for compatibility before it ships. Live pricing for each part number appears in the tables further down this page.

DL380 Gen10 Platform at a Glance

  • Processors: one or two Intel Xeon Scalable CPUs — 1st Generation (up to 28 cores, DDR4-2666) or 2nd Generation (up to 28 cores, DDR4-2933)
  • Memory: 24 DIMM slots (12 per processor) — up to 1.54TB of RDIMM, 3TB of LRDIMM, or 6TB with Intel Optane Persistent Memory on 2nd Gen CPUs
  • Storage: 8SFF, 24SFF, and 12LFF front ends with mid-tray and rear cage options — up to 30 SFF drives or 19 LFF + 2 SFF, plus NVMe bay options
  • Networking: embedded 4 × 1GbE (on standard models), a FlexibleLOM slot, and PCIe stand-up adapters
  • Power: Flex Slot hot-plug power supplies — 500W, 800W (Platinum and Titanium), and 1600W
  • Management: HPE iLO 5 with Intelligent Provisioning

Know which CPU generation you have. The DL380 Gen10 runs 1st Gen (DDR4-2666) or 2nd Gen (DDR4-2933) Xeon Scalable processors, and the installed generation sets your memory speed and Optane Persistent Memory eligibility — check the CPU model in iLO before ordering.

Full platform detail is in the official HPE DL380 Gen10 QuickSpecs.

Shop DL380 Gen10 Parts by Category

Comparing generations? See DL380 Gen10 Plus parts, DL380 Gen11 parts, our guide to how Gen10 and Gen11 compare, or browse all HPE parts by server model.

DL380 Gen10 Parts FAQ

Is the HPE ProLiant DL380 Gen10 still worth buying parts for?
Yes - it remains one of the most widely deployed 2U servers in the field, genuine parts are plentiful in new and refurbished condition, and upgrade economics are excellent. It's a mainstay for production, lab, backup, and cost-sensitive environments alike.

How much memory does the DL380 Gen10 support?
24 DDR4 DIMM slots (12 per processor): up to 1.54TB with 64GB RDIMMs, 3TB with 128GB LRDIMMs, or up to 6TB combining Intel Optane Persistent Memory (12 x 512GB) with DRAM on 2nd Gen Xeon CPUs.

What drives does the DL380 Gen10 accept?
Hot-plug Smart Carrier (SC) SAS, SATA, and NVMe drives - up to 30 SFF (24 front + 6 rear), or 12LFF front ends expandable to 19 LFF + 2 SFF with the mid-tray and rear cages, plus dedicated NVMe bay options.

What is the difference between 1st Gen and 2nd Gen Xeon Scalable in the DL380 Gen10?
Both fit the same server: 1st Gen (Skylake) tops out at 28 cores with DDR4-2666, while 2nd Gen (Cascade Lake) reaches 28 cores with DDR4-2933 support and adds Intel Optane Persistent Memory capability. The installed CPU generation sets your memory speed.

Can I mix new and refurbished parts in the DL380 Gen10?
Yes. Genuine HPE parts perform identically whether new or refurbished, and our refurbished stock is tested before shipping - the standard way to expand this platform economically.

✅ Looking for a specific DL380 Gen10 part? Browse our full selection below.

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