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P40552-B21
P40552-B21 HPE 375GB NVMe Gen3 High Performance Low Latency Write Intensive SFF BC U.2 P4800X SSD
- Estimated Release:
- 2023
- Form Factor/Carrier Type:
- SFF / Basic Carrier (BC)
- Form Factor:
- SFF (2.5 inch)
- Hotplug Carrier Type:
- Basic Carrier (BC)
- SSD Interface:
- NVMe (U.2)
- SSD Storage Capacity:
- 0.375 TB [375 GB]
- SSD Workload Type:
- Write Intensive
- Collection:
- HPE Server SSD
- Collection URL:
- /hpe-server-ssd.htm
This item, P40552-B21, is the HPE option part number for the product described as 375GB NVMe Gen3 High Performance Low Latency Write Intensive SFF BC U.2 P4800X SSD. Further details below.
Elevate your server's performance with the HPE 375GB NVMe Gen3 SSD (P40552-B21). Designed for high performance and low latency, this 2.5" SSD offers an impressive 2550 MBps read and 2150 MBps write speeds, ensuring that your data handling is smoother and faster than ever. Compatible with a range of HPE Gen10 and Gen11 servers, it supports intensive workloads with an incredible endurance of 20,500 TBW, providing reliability and efficiency in server operations.
HPE Option Part #: P40552-B21
HPE Spare Part #: P41550-001
PRODUCT SPECIFICATIONS FOR P40552-B21:
- Device Type: Solid state drive - hot-swap
- Capacity: 375 GB
- NAND Flash Memory Type: Multi-level cell (MLC)
- Form Factor: 2.5" SFF
- Interface: U.2 PCIe 3.0 (NVMe)
- Features: Digitally Signed Firmware, High Performance, low latency
- Height: 0.6 in
- Weight: 17.64 oz
- Bundled with: HPE Basic Carrier
- Drive Writes Per Day (DWPD): 30
- SSD Endurance: 20500 TB
- Internal Data Rate: 2550 MBps (read) / 2150 MBps (write)
- 4KB Random Read: 585000 IOPS
- 4KB Random Write: 550000 IOPS
- Interfaces: 1 x PCI Express 3.0 U.2 (NVMe)
- Compatible Bay: 2.5" SFF
- Power Consumption: 4 Watt (idle) | 5.16 Watt (random read) | 5.16 Watt (random write) | 8.5 Watt (sequential read) | 12.2 Watt (sequential write) | 5.16 Watt (random read/write) | 13 Watt (maximum)
COMPATIBLE WITH:
PROLIANT ML SERIES
PROLIANT DL SERIES
** This list may not be complete. Contact us via Live Chat if you have any questions about compatibility.
FREQUENTLY ASKED QUESTIONS FOR P40552-B21:
- What servers are compatible with the P40552-B21?
The P40552-B21 is compatible with HPE DL20 Gen10 Plus, DL320 Gen11, DL325 Gen10 Plus V2, DL325 Gen11, DL345 Gen10 Plus, DL345 Gen11, DL360 Gen10 Plus, DL360 Gen11, DL380 Gen10 Plus, DL380 Gen11, DL385 Gen10 Plus V2, and DL385 Gen11 servers. - What is the endurance rating of the P40552-B21 SSD?
The P40552-B21 SSD boasts an impressive endurance rating of 20,500 TBW, supporting up to 30 drive writes per day. - How does the P40552-B21 ensure data security?
The P40552-B21 includes digitally signed firmware, enhancing data security and ensuring integrity during transfers.
HPE PARTSURFER INFO FOR P40552-B21
| Spare PN | Description | |
|---|---|---|
| P41550-001 | SPS-DRV SSD 375GB SFF NVMe WI U.2 BC |
Last Updated: 2026-06-24
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This product is warrantied against hardware failure for a period of 3 Years from the date of purchase. Before making a purchase, please take a moment to review our return policy below.
Returns
It is the customer's responsibility to verify compatibility with their machine(s) before placing an order. If an item is ordered by mistake, it can be returned for refund, minus a 25% restocking fee, within 5 business days of receipt. The cost of freight is not refundable.
Please be aware that factory-sealed equipment can only be returned if it remains unopened.
Defective Products
If you have received a defective part and your machine is still within the HPE warranty period, please initiate a warranty exchange by visiting the HPE Enterprise Support Center. Be sure to have the serial numbers of the defective drive and your server/storage array handy.
In case your hardware becomes defective during the Global One warranty period, but the HPE warranty has expired, you can return the product to us for a working replacement. You are responsible for the shipment of returned merchandise. However, we will cover the expense of Ground /Economy shipment for the replacement item(s).
Requesting an RMA
To initiate a return or warranty claim, please complete and submit the RMA Request Form.


