P49053-B21 is the HPE option part number for 3.2TB SAS 24G Mixed Use SFF BC Multi Vendor SSD. It is a hot-swap 2.5-inch small form factor solid state drive with a single SAS 24Gb/s interface and a drive transfer rate of 22.5 Gb/s external, shipped mounted in an HPE Basic Carrier for direct installation into an SFF drive bay. The Mixed Use classification targets workloads that combine sustained reads with a significant write component. Supported platforms include ProLiant Gen10 Plus, Gen11 and Gen12 servers such as the DL360 Gen10 Plus, DL380 Gen11, DL385 Gen11 and DL380 Gen12, along with ML-series towers configured for SFF drive bays.
HPE Option Part #: P49053-B21
HPE Spare Part #: P49749-001
HPE Model #: MO003200PXDCD, MO003200PXMTV, MO003200PYHRT, MO003200PZWSK
HPE Assembly Part #: P49336-001
PRODUCT SPECIFICATIONS FOR P49053-B21:
- Device Type: Solid state drive - hot-swap
- Capacity: 3.2 TB
- Form Factor: 2.5" SFF
- Interface: SAS 24Gb/s
- Bundled with: HPE Basic Carrier
- Drive Class: Mixed Use
- Drive Transfer Rate: 22.5 Gb/s (external)
- Interfaces: 1 x SAS 24Gb/s
- Compatible Bay: 2.5" SFF
COMPATIBLE WITH:
PROLIANT ML SERIES
PROLIANT DL SERIES
** This list may not be complete. Contact us via Live Chat if you have any questions about compatibility.
FREQUENTLY ASKED QUESTIONS ABOUT P49053-B21
What is the difference between P49053-B21 and P49749-001?
They are the same physical drive under different HPE numbering schemes. P49053-B21, the subject of this page, is the option part number: the orderable configuration number used when specifying the drive as part of a server build. P49749-001 is the spare part number, used for service replacement of an already installed drive. The same family also includes one assembly revision and four OEM drive models, all listed in the cross-reference block on this page.
What is an assembly part number, and what is an OEM model number?
An assembly part number identifies a specific build revision of the drive as HPE assembled it, and is typically referenced in manufacturing and service documentation rather than in ordering. An OEM model number is the drive manufacturer's own identifier, printed on the drive label; because this is a Multi Vendor SSD, HPE sources it from more than one manufacturer, which is why four OEM model numbers map back to this single option number.
Which servers accept P49053-B21?
It is supported in HPE ProLiant Gen10 Plus, Gen11 and Gen12 systems with 2.5-inch SFF bays: ML30 Gen10 Plus, DL20 Gen10 Plus, DL325 Gen10 Plus v2, DL345 Gen10 Plus, DL360 Gen10 Plus, DL365 Gen10 Plus, DL380 Gen10 Plus, DL385 Gen10 Plus v2, ML30/ML110/ML350 Gen11, DL20, DL320, DL325, DL345, DL360, DL365, DL380, DL385 and DL560 Gen11, plus ML350, DL320, DL340, DL345, DL360, DL380 and DL580 Gen12.
Does the drive include a carrier?
Yes. P49053-B21 is bundled with the HPE Basic Carrier and ships as a complete hot-swap assembly for a 2.5-inch SFF bay. No separate tray or adapter is required for the SFF bays on the supported ProLiant platforms. Because it is hot-swap, the drive can be inserted or removed while the server remains powered, subject to the controller and array configuration in use.
What does the Mixed Use drive class mean here?
Mixed Use is HPE's endurance classification for SSDs intended for workloads that combine reads and writes, rather than read-dominated or write-intensive extremes. At 3.2 TB on a SAS 24Gb/s interface with a 22.5 Gb/s external transfer rate, this drive is positioned for general-purpose virtualization, database and application storage in Gen10 Plus through Gen12 ProLiant servers where write activity is regular but not the dominant workload.
HPE PARTSURFER INFO FOR P49053-B21
| Spare PN | Description | |
|---|---|---|
 | P49749-001 | SPS-DRV SSD 3.2TB SFF SAS MU BC MV |
Last Updated: 2026-09-01
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- Estimated Release
- 2023
- Form Factor
- SFF (2.5 inch)
- Form Factor/Carrier Type
- SFF / Basic Carrier (BC)
- Hotplug Carrier Type
- Basic Carrier (BC)
- SSD Data Transfer Rate
- 24 Gb/sec (24G)
- SSD Interface
- SAS (12G/24G)
- SSD Storage Capacity
- 3.2 TB
- SSD Workload Type
- Mixed Use
This product is warrantied against hardware failure for a period of 3 Years from the date of purchase. Before making a purchase, please take a moment to review our return policy below.
Returns
It is the customer's responsibility to verify compatibility with their machine(s) before placing an order. If an item is ordered by mistake, it can be returned for refund, minus a 25% restocking fee, within 5 business days of receipt. The cost of freight is not refundable.
Please be aware that factory-sealed equipment can only be returned if it remains unopened.
Defective Products
If you have received a defective part and your machine is still within the HPE warranty period, please initiate a warranty exchange by visiting the HPE Enterprise Support Center. Be sure to have the serial numbers of the defective drive and your server/storage array handy.
In case your hardware becomes defective during the Global One warranty period, but the HPE warranty has expired, you can return the product to us for a working replacement. You are responsible for the shipment of returned merchandise. However, we will cover the expense of Ground /Economy shipment for the replacement item(s).
Requesting an RMA
To initiate a return or warranty claim, please complete and submit the RMA Request Form.
