HPE ProLiant ML350 Gen10 Parts

4U tower server1st and 2nd Gen Intel Xeon Scalable

The HPE ProLiant ML350 Gen10 is a 4U tower server, convertible to a rack mount, for up to two 1st or 2nd Gen Intel Xeon Scalable processors (one for U models, such as the Gold 6208U), and the processor's generation decides its memory: DDR4-2666 kits for 1st Gen, DDR4-2933 for 2nd Gen. This page lists the 315 parts HPE's QuickSpecs have listed for it across editions, by part type.

  • 315 HPE-listed parts
  • 24 DIMM slots, up to 3TB
  • Up to 24 SFF or 12 LFF drives
  • 8 PCIe 3.0 slots
  • Flex Slot power, 500W to 1600W

Specifications: HPE QuickSpecs a00021852enw, version 44 (July 28, 2025), which HPE has retired. Memory and drive figures match the ML350 Gen10 Memory and Drives pages.

Shop ML350 Gen10 parts by type

More ML350 Gen10 parts: chassis, expansion and enablement

Most ordered from this list

The parts on this page our customers order most, for any server.

  1. Drives872479-B211.2TB SAS 12G Mission Critical 10K SFF SC Multi Vendor HDD
  2. MemoryP00924-B2132GB (1x32GB) Dual Rank x4 DDR4-2933 CAS-21-21-21 Registered Smart Memory Kit
  3. Memory815100-B2132GB (1x32GB) Dual Rank x4 DDR4-2666 CAS-19-19-19 Registered Smart Memory Kit
  4. Drives872477-B21600GB SAS 12G Mission Critical 10K SFF SC Multi Vendor HDD
  5. Drives881457-B212.4TB SAS 12G Mission Critical 10K SFF SC 512e Multi Vendor HDD
  6. Network adapters811546-B21Ethernet 1Gb 4-port BASE-T I350-T4V2 Adapter
  7. Drives872481-B211.8TB SAS 12G Mission Critical 10K SFF SC 512e Multi Vendor HDD
  8. Drives765466-B212TB SAS 12G Midline 7.2K SFF (2.5in) SC 512e HDD
  9. Power supplies865414-B21800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit
  10. Drives870753-B21300GB SAS 12G Enterprise 15K SFF (2.5in) SC Digitally Signed Firmware HDD

ML350 Gen10 at a glance

Processors

One or two Intel Xeon Scalable processors of the same model, 1st Gen (model numbers x1xx) or 2nd Gen (x2xx). U models, such as the Gold 6208U, are single-socket only. HPE does not support a field upgrade from 1st to 2nd Gen.

HPE ships processors above 85W with the Performance heat sink and the others with the Standard heat sink, and two processors need the Redundant Fan Cage Kit (874572-B21). The Gold 6256, 6250 and 6250L are not supported at the Optimal Cooling thermal setting. ML350 Gen10 Processors

Memory

24 DIMM slots, 12 per processor on 6 channels; slots 13 to 24 need the second processor. DDR4-2666 kits for 1st Gen, DDR4-2933 for 2nd Gen.

Up to 3TB with 128GB LRDIMMs in all 24 slots and two processors whose model number ends in M or L; other processors address up to 768GB (1st Gen) or 1TB (2nd Gen) each. 1.5TB with 64GB RDIMMs; RDIMMs and LRDIMMs do not mix.

HPE's version 44 option list stops at the 64GB RDIMM. The 128GB LRDIMMs on this list (P00928-B21 and P11040-B21 for 2nd Gen, 815102-B21 for 1st Gen) come from earlier editions. ML350 Gen10 Memory

Drives

Up to 24 SFF drives in three 8 SFF cages or 12 LFF drives in three 4 LFF cages. The 4 LFF chassis can mix SFF and LFF cages, and the non-hot-plug LFF model takes SATA drives only. The media bays and optical drive bay take the place of one cage, so with either fitted, at most two cages fit.

A field upgrade to 24 SFF or 12 LFF needs the Redundant Fan Cage Kit, and HPE's 24 SFF configuration has the SAS Expander in PCIe slot 4.

The 8 SFF NVMe Express Bay (874569-B21) takes up to 8 NVMe SSDs, one bay per server, SFF chassis only. It goes in drive box 2, so with it the server holds 16 SFF drives plus 8 NVMe SSDs. For 8 NVMe drives it needs both of its riser boards (4 with one), and they go in PCIe slots 1 and 3.

NVMe drives need the fan kit and do not run on Smart Array controllers. 10K and 15K SAS drives need the fan kit too. SATA M.2 SSDs go on the M.2 enablement card (878783-B21), one per server, on the S100i only, and need the fan kit as well. ML350 Gen10 Drives

Storage controllers

Embedded S100i software RAID for SATA drives, UEFI mode and Windows only, off until enabled; adding the second and third LFF cages on the S100i needs the LFF Embedded SATA Cable Kit (877578-B21).

Smart Array E208i, E208e, P408i, P408e, P816i-a and P824i-p controllers. Performance RAID controllers need a Smart Storage Battery (P01367-B21) or Hybrid Capacitor (P02381-B21), each internal controller needs its ML350 Gen10 cable kit, and the P816i-a needs the Redundant Fan Cage Kit. ML350 Gen10 Storage Controllers

Networking

4 x 1GbE embedded ports, which do not run at 100MB/s or 10MB/s, PCIe adapters and a dedicated 1Gb iLO port. Some adapters, such as the 10Gb BCM57416 (813661-B21), need the Redundant Fan Cage Kit. ML350 Gen10 Networking Adapters

Expansion

8 PCIe 3.0 slots: slots 1 to 4 on processor 1, slots 5 to 8 on processor 2, which need the second processor.

Fans

One-processor models typically ship with two rear fans, which are not hot-plug. The Redundant Fan Cage Kit (874572-B21) adds four hot-plug fans, six in all; HPE requires it with two processors, in rack mode, with the front fully populated, in ASHRAE 3 or 4 environments, with 10K or 15K SAS drives, NVMe or M.2 drives, and with GPUs, InfiniBand cards, higher-end network adapters and the P816i-a and P824i-p controllers.

An internal LTO tape drive goes in media bay 1 and needs the Media Drive Support Kit (874570-B21). With the fan kit, fan 1 gives way to a blank and the server runs without fan redundancy. HPE also requires the Increased Cooling thermal setting in RBSU with an internal LTO tape drive. Server-specific options

Power

Flex Slot hot-plug power supplies from 500W to 1600W, including 800W -48VDC and 800W high-voltage AC/DC models. HPE does not allow two different power supplies in one server. A server built with the 500W non-hot-plug supply needs the RPS enablement kit (874571-B21) for Flex Slot supplies. ML350 Gen10 Power Supplies

Management

HPE iLO 5.

Specifications from HPE QuickSpecs a00021852enw, version 44 (July 28, 2025). Memory figures match the ML350 Gen10 Memory page.

Before you order memory or processors, check the processor generation. On Xeon Scalable processors named Bronze, Silver, Gold or Platinum, the second digit of the model number is the generation: a 1 (x1xx) is 1st Gen and takes DDR4-2666 kits; a 2 (Gold 6230R, Silver 4210R) is 2nd Gen and takes DDR4-2933 kits. HPE does not support a field upgrade from 1st to 2nd Gen, and two processors must be the same model. A 4 or 5 (Gold 6430, Gold 6530) means the server is an ML350 Gen11. Find the model in iLO under System Information › Processors.

Complete your ML350 Gen10 build

Gen9, Gen10 or Gen11? How to tell

The processor model number tells the three ML350 generations apart, and it decides the memory you can buy.

What to checkML350 Gen9ML350 Gen10 This pageML350 Gen11
Processor model numbersE5-2600 v3 or v4: E5-2650 v3, E5-2650 v4, E5-2690 v4x1xx or x2xx: Gold 6230R, Silver 4210R, Silver 4208x4xx or x5xx: Gold 6430, Gold 6530
MemoryDDR4-2133 or DDR4-2400, 24 slotsDDR4-2666 or DDR4-2933, 24 slotsDDR5-4800 or DDR5-5600, 32 slots
Memory kits look like805351-B21, 728629-B21P00922-B21, P00924-B21P43322-B21, P64705-B21
Parts pageML350 Gen9 partsYou are hereML350 Gen11 parts

From the HPE QuickSpecs of each server: HPE ProLiant ML350 Generation9 (Gen9) c04346270 version 31; HPE ProLiant ML350 Gen10 a00021852enw version 44; HPE ProLiant ML350 Gen11 a50004308enw version 48.

All 315 ML350 Gen10 parts

Grouped by part type; within each group the parts are in the order of HPE's QuickSpecs. Open a group, or type a part number or a few words to filter the whole list.

ML350 Gen10 parts questions

How much memory does the ML350 Gen10 support?

Up to 3TB with two processors: 24 slots with 128GB DDR4 LRDIMMs in every one, which needs processors whose model number ends in M or L. Other processors address up to 768GB each (1st Gen) or 1TB each (2nd Gen). With registered DIMMs the maximum is 1.5TB (64GB DDR4-2933 RDIMMs in every slot), and RDIMMs and LRDIMMs do not mix. HPE's version 44 option list stops at the 64GB RDIMM; the 128GB LRDIMMs on this list come from earlier editions. A single processor can use only its 12 slots. 1st Gen Intel Xeon Scalable processors take DDR4-2666 kits and 2nd Gen processors take DDR4-2933 kits.

Which drives fit the ML350 Gen10?

2.5-inch SFF drives on the Smart Carrier (SC) in SAS or SATA, and SFF NVMe SSDs (SCN) in the 8 SFF NVMe Express Bay; 3.5-inch LFF drives on the Low Profile (LP) carrier in SAS or SATA and LFF SSDs on the LPC carrier; RW SATA drives for the non-hot-plug LFF model; and SATA M.2 SSDs on the universal M.2 enablement card. With the Express Bay, the server holds 16 SFF drives plus 8 NVMe SSDs. The 4 LFF chassis can mix SFF and LFF cages. Which interfaces work depends on the controller.

How do I tell which processor generation my ML350 Gen10 has?

Read the processor model in iLO under System Information › Processors. On these Bronze, Silver, Gold and Platinum models the second digit of the model number is the generation: a 1 means 1st Gen, a 2 (Gold 6230R, Silver 4210R, Silver 4208) means 2nd Gen. It decides the memory kit: DDR4-2666 for 1st Gen, DDR4-2933 for 2nd Gen. It also decides the processor: HPE does not support a field upgrade from 1st to 2nd Gen, and two processors must be the same model.

Is my server an ML350 Gen10, a Gen9 or a Gen11?

Check the processor model number. The Gen10 runs 1st or 2nd Gen Xeon Scalable processors named Bronze, Silver, Gold or Platinum (x1xx or x2xx, such as Gold 6230R) with DDR4-2666 or DDR4-2933 memory in 24 slots. The Gen9 runs Xeon E5-2600 v3 or v4 processors (such as E5-2650 v4) with DDR4-2133 or DDR4-2400 memory, also in 24 slots. The Gen11 runs 4th or 5th Gen Xeon Scalable processors, also named Bronze to Platinum (x4xx or x5xx, such as Gold 6430), with DDR5-4800 or DDR5-5600 memory in 32 slots. Memory kits and processors differ between them, so buy those from the page for your generation.

Are refurbished parts on this list too?

Yes. A refurbished part carries the same HPE part number as a new one, so it is listed here under that number, and each listing shows its condition. Every part ships tested or factory sealed.

What warranty comes with ML350 Gen10 parts?

A replacement warranty of 1 to 5 years, depending on the part: memory is covered for 5 years, and many other parts for 1 or 3 years.

Other ML350 generations

ML350p Gen8 partsML350e Gen8 partsML350 Gen9 partsML350 Gen11 partsML350 Gen12 partsAll HPE parts by server model
Ships same dayMost orders ship the same business day
1 to 5 year warrantyTested or factory sealed
Purchase orders acceptedCard, P-card, ACH, wire or PayPal too
Drives150 parts

All drives on the ML350 Gen10 Drives page

Hard Disk Drives

Enterprise - 12G SAS - SFF HDD
HPE note

HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21) is required for 10K, 15K or higher RPM SAS drives.

Midline - 12G SAS - SFF HDD
Midline - 12G SAS - LFF HDD
Midline - 6G SATA - SFF HDD
Midline - 6G SATA - LFF HDD
6G SATA - LFF NHP/Raw HDD

Solid State Drives

HPE note

Best product availability is limited to US, Canada, and Latin America at this time.

Write Intensive - 12G SAS - SFF - SSD
Read Intensive - 12G SAS - SFF - SSD
Read Intensive - 6G SATA - SFF - SSD
Read Intensive & Mixed Use - 6G SATA - LFF - SSD
Mixed Use - 12G SAS - SFF - SSD
Mixed Use - 6G SATA - SFF - SSD
Mixed Use - 12G SAS - LFF - SSD
Read Intensive - 6G SATA - M.2 - SSD
HPE notes (6)
  • - HPE Universal SATA HHHL M.2 Kit (878783-B21) and use S100i SATA controller only.
  • - M.2 supports Software RAID only.
  • - HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21) is required for M.2 drives.
  • - HPE has qualified the M.2 drive portfolio using the Operating System inbox drivers, full detail on the
  • HPE Solid State Drive QuickSpecs.

NVMe - SFF - Solid State Drives

HPE notes (8)
  • - HPE ML350 Gen10 8SFF NVMe SSD Express Bay Enablement Kit with 2x4NVMe Risers and Support Cables (874569-B21) is required to support installation of these drives.
  • - Max. support is one Gen10 ML350 NVMe 8SFF Exp Bay Kit (874569-B21) which can support up to 8 NVMe solid state drives.
  • - NVMe drives require the addition of HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21).
  • - When used to run high-performance workloads, NVMe SSDs can cause the fans to operate at high speeds to maintain optimum system cooling. This high-speed fan operation leads to a sound pressure level of between 50 dB(A) to 55 dB(A). Hewlett Packard Enterprise recommends taking this possible acoustic condition into consideration when selecting a site for a server that has NVMe SSDs installed.
  • - Not supported by HPE Smart Array controllers.
  • - HPE has qualified the NVMe drive portfolio using the Operating System inbox drivers,full detail on the HPE Solid State Drive QuickSpecs.
  • - Alternatively, customers can choose the NVMe SSDs in PCIe adapter cards form factor. Refer to the next session for option support detail.
NVMe - PCIe Adapter Cards - SSD
HPE NVMe x8 Lanes Mixed Use HHHL
Memory15 parts

All memory on the ML350 Gen10 Memory page

HPE notes (7)
  • For new Gen10 memory population rule whitepaper and optimal memory performance guidelines, please go to:
  • (link)
  • For Gen10 memory speed table, please go to: (link)
  • For memory Reliability, Accessibility, Serviceability (RAS) features whitepaper like Gen10 Fast Fault Tolerance and legacy mirrored memory feature etc. please go to: (link)
  • - Maximum memory capacity and speed per processor is dependent on processor model selection or limitation.
  • - DDR4-2933 Memory Kits are only supported with 2nd Generation Intel Xeon Scalable Series Processors and DDR4-2666 Memory Kits are only supported with 1st Generation Intel Xeon Scalable Series Processors.

HPE DDR4 Memory

Registered DIMMs (RDIMMs) for 2nd Generation Intel Xeon Scalable Series
Registered DIMMs (RDIMMs) for 1st Generation Intel Xeon Scalable Series
Load Reduced DIMMs (LRDIMMs) for 2nd Generation Intel Xeon Scalable Series
Load Reduced DIMMs (LRDIMMs) for 1st Generation Intel Xeon Scalable Series
Network adapters18 parts

All network adapters on the ML350 Gen10 Networking Adapters page

1 Gigabit Ethernet adapters

10 Gigabit Ethernet adapters

25 Gigabit Ethernet adapters

100 Gigabit Ethernet adapters

Storage controllers8 parts

All storage controllers on the ML350 Gen10 Storage Controllers page

HPE note

The Gen10 controller naming framework has been updated to simplify identification as depicted below. For a more detailed breakout of the available Gen10 Smart Array controllers visit the HPE Smart Array Gen10 Controllers Data Sheet.

Performance RAID Controllers

HPE note

All performance RAID controllers are supported by the HPE Smart Storage Battery (P01367-B21), or HPE Smart Storage Hybrid Capacitor (P02381-B21) which supports multiple devices and is sold separately.

Essential RAID Controllers

Power supplies7 parts

All power supplies on the ML350 Gen10 Power Supplies page

HPE Power Supply Options
Processors59 parts

All processors on the ML350 Gen10 Processors page

Intel Second Generation Xeon Scalable Processors

Gold Processors
Silver Processors
Bronze Processors

Intel Second Generation XeonProcessors

Platinum Processors
HPE note

Speed Select Processor model enhanced by IntelSpeed Select Technology to run at three distinct operating points.

Gold Processors
Silver Processors
Bronze Processors
Fibre Channel HBAs12 parts
Emulex Fibre Channel HBAs
QLogic Fibre Channel HBAs
Converged Network Adapters
InfiniBand adapters3 parts
Server-specific options17 parts
Smart Storage battery2 parts
Optical drives3 parts
Tape backup15 parts
HPE note

Internal half-height (5.25”) tape devices are supported in ML350 Gen10 and require the HPE ML350 Gen10 Media Drive Support Kit (874570-B21). In the case when LTO Internal Tape is selected along with the Fan Redundant Kit, Fan#1 will need to be removed and the Fan Blank provided in this option kit will need to be installed in Fan#1 location. This configuration will run without fan redundancy. Refer to ML350 Gen10 User Guide for more detail. Installation of the internal LTO tape drive is limited in media bay 1.

HPE Tape Drives

HPE Tape Backup Products

HPE RDX Products

Security1 part
  • 864279-B21 HPE Trusted Platform Module 2.0 Gen10 Option
    HPE note

    HPE Trusted Platform Module 2.0 option works with Gen10 servers with UEFI Mode not Legacy Mode. It is not compatible with HPE ProLiant Gen8 servers or earlier generation variants. HPE server systems can have a TPM module (of any type) installed only once. It cannot be replaced with any other TPM module. There is a FIO setting to allow this TPM module to operate in a TPM 1.2 mode (872108-B21).

GPUs1 part

HPE Computation and Graphics Accelerators

  • R9H23C NVIDIA A2 16GB PCIe Non-CEC Accelerator for HPE
    HPE note

    HPE ML350 Gen10 Redundant Fan Cage Kit (874572-B21) is required. This GPU model is supported with the 2nd generation of Intel Xeon Scalable Processors only. It was tested with the 1st generation of Intel Xeon Scalable Processors also but support is limited to LVO and private only.

USB and SD options2 parts
Hard drive kits9 parts
Media/ODD Bay Kits

Hard Drive Blank Kits

Cable options and SAS expander kit8 parts
Ships same dayMost orders ship the same business day
1 to 5 year warrantyReplacement coverage on every part
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