HPE ProLiant ML350 Gen12 Parts

4U tower serverIntel Xeon 6

The HPE ProLiant ML350 Gen12 is a 4U tower server, convertible to a rack mount, for one or two Intel Xeon 6 processors, and it takes one memory family: HPE DDR5-6400 registered kits, not the DDR5-4800 or DDR5-5600 kits of the ML350 Gen11. This page lists the 266 parts HPE's QuickSpecs have listed for it across editions, by part type.

  • 266 HPE-listed parts
  • 32 DIMM slots, up to 8TB
  • Up to 24 SFF, 12 LFF or 12 E3.S drives
  • Up to 10 PCIe 5.0 slots on 3 risers
  • Flex Slot power, 800W to 1800W-2200W

Specifications: HPE QuickSpecs a50006995enw, version 18 (October 5, 2026), in which HPE calls the server “HPE ProLiant Compute ML350 Gen12”. Memory and drive figures match the ML350 Gen12 Memory and Drives pages.

Shop ML350 Gen12 parts by type

More ML350 Gen12 parts: chassis, expansion and enablement

Most ordered from this list

The parts on this page our customers order most, for any server.

  1. DrivesP28352-B212.4TB SAS 12G Mission Critical 10K SFF BC 512e Multi Vendor HDD
  2. MemoryP69727-B2132GB (1x32GB) Dual Rank x8 DDR5-6400 CAS-52-52-52 EC8 Registered Smart Memory Kit
  3. Drives861686-B211TB SATA 6G Business Critical 7.2K LFF LP Multi Vendor HDD
  4. DrivesP28586-B211.2TB SAS 12G Mission Critical 10K SFF BC Multi Vendor HDD
  5. Boot devicesP78279-B21NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device
  6. DrivesP47808-B21960GB SATA 6G Read Intensive LFF LPC Multi Vendor SSD
  7. Drives881787-B2112TB SATA 6G Business Critical 7.2K LFF LP Helium 512e Multi Vendor HDD
  8. Drives861683-B214TB SATA 6G Business Critical 7.2K LFF LP Multi Vendor HDD
  9. DrivesP40500-B213.84TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
  10. DrivesP40505-B213.84TB SATA 6G Mixed Use SFF BC Multi Vendor SSD

ML350 Gen12 at a glance

Processors

One or two Intel Xeon 6 processors of the same model, 6700P or 6500P series.

Processor kits come without heat sinks or fans: the Standard Heat Sink (P72358-B21) below 225W, the Performance Heat Sink (P72359-B21) at 225W or more, one per processor. A second processor needs the Second CPU Fan Kit (P47902-B21), and processors of 300W or more also need the Redundant Fan Kit (P47219-B21). ML350 Gen12 Processors

Memory

32 DIMM slots, 16 per processor on 8 channels; one processor uses its 16. HPE DDR5-6400 registered kits only, 32GB to 256GB: 6400 MT/s with one DIMM per channel, 5200 MT/s with two.

Up to 8TB with 256GB RDIMMs in all 32 slots, 4TB with one processor; 256GB memory needs the Redundant Fan Kit and the Second CPU Fan Kit. Install 1, 2, 4, 8, 12 or 16 DIMMs per processor; 64GB, 96GB, 128GB and 256GB kits cannot be mixed with any other capacity, and x4 and x8 DIMMs do not mix. ML350 Gen12 Memory

Drives

No drive cage as standard; up to three cages. 8SFF x1 Tri-Mode (P72318-B21) and 4LFF (P72357-B21) cages take up to 24 SFF or 12 LFF drives, each cage on a controller and cable kit.

8SFF x4 NVMe cages (P72316-B21) take 16 NVMe drives in two cages with x4 cable kits or 24 in three with x2 cable kits; direct attached, the second processor is needed for two cages on x4 cable kits or a third cage on x2 cable kits.

One 12EDSFF cage (P72320-B21) takes 12 E3.S drives. It needs two processors direct attached or two MR932i-p controllers, both fan kits and a 25°C inlet. Its included rear fan covers the primary riser cage, so nothing can be connected there. NVMe x4 and 12EDSFF cages do not mix.

An internal LTO tape drive goes in box 1. It needs the Tertiary Riser Kit (P79317-B21), an LTO cable kit (P77437-B21 or P77438-B21) and a free port on an MR216i or MR408i controller. HPE requires the Increased Cooling thermal setting in RBSU with it, and the server then takes two cages at most.

The NS204i-u v2 boot device needs the Second CPU Fan Kit and a front (P74252-B21) or rear (P72360-B21) enablement kit. The front kit rules out an internal LTO tape drive. With the NS204i-u, three drive cages and no Redundant Fan Kit, the inlet is limited to 25°C. ML350 Gen12 Drives

Storage controllers

The 8SFF x1 and 4LFF cages need a controller; NVMe drives can run direct attached on Intel VROC NVMe, UEFI mode only. MR216i, MR408i and MR416i tri-mode controllers, OCP and PCIe; the MR932i-p for NVMe SSDs in the x4 and 12EDSFF cages only; the Smart Array E208e-p for external drives.

Controllers with cache need the 96W Smart Storage Battery or a Smart Hybrid Capacitor, and OCP controllers go only in the OCP A slot. ML350 Gen12 Storage Controllers

Networking

No embedded network ports: an OCP 3.0 or a stand-up PCIe adapter is required. Up to two OCP adapters; OCP B is the default slot for a networking adapter. An OCP B Enablement Kit is required when installing an OCP card in the OCP B slot. x16 OCP adapters need an OCP A or OCP B x16 cable kit.

InfiniBand adapters need a x16 riser kit and the Redundant Fan Kit. With active optical cables, the inlet limit is 25°C with processors over 270W. With active optical cables and processors of 270W or less, it is 30°C with up to two LFF or Tri-Mode SFF cages. With direct attach cables, it is 30°C with any cages. A dedicated 1Gb iLO port. ML350 Gen12 Networking Adapters

Expansion

Up to 10 PCIe 5.0 slots: 4 on the primary riser, 4 on the secondary and 2 on the tertiary riser, which need processor 2. The 2x16 primary and secondary riser kits give two x16 slots in place of four x8. Riser cards

Fans

Three fans as standard. The Second CPU Fan Kit (P47902-B21) is required with a second processor, the Redundant Fan Kit, the NS204i-u v2 or the tertiary riser.

The Redundant Fan Kit (P47219-B21) is required with processors of 300W or more, EDSFF drives, SAS4 24G Mixed Use SSDs, 256GB memory, 200Gb or faster Ethernet or InfiniBand, and GPUs.

The External GPU Fan Kit (P47220-B21), up to two, covers the rear of the riser cages, so nothing can be connected to the primary or secondary riser. With GPUs, HPE's inlet limits fall as drive cages are added: for the L40, 27°C with one cage, 25°C with two and 23°C with three. Fan kits

Power

Flex Slot hot-plug power supplies from 800W to 1800W-2200W, including a 1600W -48VDC model. The 1600W Platinum and 1800W-2200W need 200-240VAC. HPE does not support mixing two different power supplies. ML350 Gen12 Power Supplies

Management

HPE iLO 7. Management hardware

Specifications from HPE QuickSpecs a50006995enw, version 18 (October 5, 2026). Memory figures match the ML350 Gen12 Memory page.

Before you order memory or processors, make sure the server is a Gen12, not a Gen11. Both have 32 DIMM slots and DDR5 memory. An ML350 Gen12 runs Intel Xeon 6 processors, with no Bronze, Silver, Gold or Platinum in the name and a model number ending in P (Xeon 6520P, 6530P); it takes only DDR5-6400 kits. An ML350 Gen11 runs Xeon Scalable processors named by tier (Gold 6430, Gold 6530) and takes DDR5-4800 or DDR5-5600 kits. Find the model in iLO under System Information › Processors.

Complete your ML350 Gen12 build

Gen10, Gen11 or Gen12? How to tell

The processor model number tells the three ML350 generations apart, and it decides the memory you can buy.

What to checkML350 Gen10ML350 Gen11ML350 Gen12 This page
Processor model numbersx1xx or x2xx: Gold 6230R, Silver 4210R, Silver 4208x4xx or x5xx: Gold 6430, Gold 65306xxxP: Xeon 6520P, 6530P
MemoryDDR4-2666 or DDR4-2933, 24 slotsDDR5-4800 or DDR5-5600, 32 slotsDDR5-6400, 32 slots
Memory kits look likeP00922-B21, P00924-B21P43322-B21, P64705-B21P69727-B21, P69728-B21
Parts pageML350 Gen10 partsML350 Gen11 partsYou are here

From the HPE QuickSpecs of each server: HPE ProLiant ML350 Gen10 a00021852enw version 44; HPE ProLiant ML350 Gen11 a50004308enw version 48; HPE ProLiant Compute ML350 Gen12 a50006995enw version 18.

All 266 ML350 Gen12 parts

Grouped by part type; within each group the parts are in the order of HPE's QuickSpecs. Open a group, or type a part number or a few words to filter the whole list.

ML350 Gen12 parts questions

How much memory does the ML350 Gen12 support?

Up to 8TB with two processors: 32 slots with 256GB DDR5-6400 RDIMMs in every one. With one processor only its 16 slots are usable, so 4TB. 256GB memory needs the Redundant Fan Kit (P47219-B21) and the Second CPU Fan Kit (P47902-B21). The kits are HPE DDR5-6400 registered DIMMs from 32GB to 256GB, at 6400 MT/s with one DIMM per channel and 5200 MT/s with two; the 64GB, 96GB, 128GB and 256GB kits cannot be mixed with any other capacity.

Which drives fit the ML350 Gen12?

2.5-inch SFF BC drives (SAS and SATA SSDs, U.3 NVMe SSDs and SAS hard drives), 3.5-inch LFF LP hard drives in SAS or SATA, LFF LPC SSDs, and E3.S EC1 NVMe SSDs. Which ones work depends on the drive cage.

Is my server an ML350 Gen12 or an ML350 Gen11?

Check the processor model in iLO under System Information › Processors. An ML350 Gen12 runs Intel Xeon 6 processors: no Bronze, Silver, Gold or Platinum in the name, and a model number ending in P, such as Xeon 6520P or 6530P. An ML350 Gen11 runs 4th or 5th Gen Xeon Scalable processors named by tier, such as Gold 6430 or Gold 6530. Both have 32 DIMM slots, but the Gen12 takes DDR5-6400 kits and the Gen11 DDR5-4800 or DDR5-5600 kits, so buy memory and processors from the page for your generation.

Some parts on this list have Gen11 or another server in their name. Do they fit the ML350 Gen12?

Yes. HPE lists some ML350 Gen12 parts under another server's name, such as the MR416i-p Gen11 controller (P47777-B21), the ML350 Gen11/Gen12 Second CPU Fan Kit (P47902-B21) and the DL3XX/ML350 Gen12 OCP slot A x16 cable kit (P72201-B21). Go by the part number, not the server in the name.

Are refurbished parts on this list too?

Yes. A refurbished part carries the same HPE part number as a new one, so it is listed here under that number, and each listing shows its condition. Every part ships tested or factory sealed.

What warranty comes with ML350 Gen12 parts?

A replacement warranty of 1 to 5 years, depending on the part: memory is covered for 5 years, and many other parts for 1 or 3 years.

Other ML350 generations

ML350p Gen8 partsML350e Gen8 partsML350 Gen9 partsML350 Gen10 partsML350 Gen11 partsAll HPE parts by server model
Ships same dayMost orders ship the same business day
1 to 5 year warrantyTested or factory sealed
Purchase orders acceptedCard, P-card, ACH, wire or PayPal too
Drives144 parts

All drives on the ML350 Gen12 Drives page

HPE Hard Disk Drives

Enterprise - 12G SAS - SFF Drives
Business Critical - 12G SAS - LFF Drives
Business Critical - 6G SATA - LFF Drives
HPE note

Requirements for MR Tri-Mode controller SED support: TPM is not required for Local Key Management as key is stored in controller. iLO Advanced is required for Remote Key Management. Key is stored in remote key manager. (Ex. ESKM).

Solid State Drives

HPE note

LFF backplane supports up to 12G SAS.

Mixed Use - 12G/24G SAS - SFF - Solid State Drives
HPE note

When SAS4 24G Mixed Use SSD drive is selected, a Redundant Fan Kit (P47219-B21) is required.

Read Intensive - 12G/24G SAS - SFF - Solid State Drives
Mixed Use – 12G SAS - LFF- Solid State Drives
Mixed Use - 6G SATA - SFF - Solid State Drives
Read Intensive - 6G SATA - SFF - Solid State Drives
Read Intensive – 6G SATA - LFF – Solid State Drives
Mixed Use - NVMe - SFF - Solid State Drives
  • P50227-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PM1735a SSD
  • P65023-B21 HPE 6.4TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
  • P63845-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
  • P63849-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
  • P63853-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
  • P70426-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PS1030 SSD
  • P70428-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PS1030 SSD
  • P61043-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 Self-encrypting FIPS 140-3 CM7 SSD
  • P61051-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 Self-encrypting FIPS 140-3 CM7 SSD
  • P61059-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 Self-encrypting FIPS 140-3 CM7 SSD
  • P91237-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 Multi Vendor SSD
  • P91239-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 Multi Vendor SSD
  • P91241-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 Multi Vendor SSD
  • P85662-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PQC27 CM9 SSD
  • P85664-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PQC27 CM9 SSD
  • P85666-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PQC27 CM9 SSD
Read Intensive – NVMe - SFF - Solid State Drives
  • P50216-B21 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PM1733a SSD
  • P64846-B21 HPE 3.84TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
  • P64848-B21 HPE 7.68TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
  • P63833-B21 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
  • P63837-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
  • P63841-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
  • P70434-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PS1010 SSD
  • P70436-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PS1010 SSD
  • P61019-B21 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 Self-encrypting FIPS 140-3 CM7 SSD
  • P61027-B21 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 Self-encrypting FIPS 140-3 CM7 SSD
  • P61035-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 Self-encrypting FIPS 140-3 CM7 SSD
  • P84244-B21 HPE 3.84TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 SPDM 7500 SSD
  • P84242-B21 HPE 7.68TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 SPDM 7500 SSD
  • P84239-B21 HPE 15.36TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 SPDM 7500b SSD
  • P91243-B21 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 Multi Vendor SSD
  • P91245-B21 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 Multi Vendor SSD
  • P91247-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 Multi Vendor SSD
  • P91249-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 Multi Vendor SSD
  • P85668-B21 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PQC27 CM9 SSD
  • P85670-B21 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PQC27 CM9 SSD
  • P85672-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PQC27 CM9 SSD
  • P85674-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PQC27 CM9 SSD
  • P85676-B21 HPE 30.72TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PQC27 CM9 SSD
Mixed Use – NVMe - EDSFF - Solid State Drives
  • P70399-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3S EC1 PS1030 SSD
  • P70401-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3S EC1 PS1030 SSD
  • P70403-B21 HPE 12.8TB NVMe Gen5 High Performance Mixed Use E3S EC1 PS1030 SSD
  • P78784-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3.S EC1 PM1755 SSD
  • P78787-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3.S EC1 PM1755 SSD
  • P77262-B21 HPE 1.6TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 EDSFF SPDM PE1030 SSD
  • P77265-B21 HPE 3.2TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 EDSFF SPDM PE1030 SSD
  • P77267-B21 HPE 6.4TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 EDSFF SPDM PE1030 SSD
  • P91098-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91100-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91102-B21 HPE 12.8TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91084-B21 HPE 1.6TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91086-B21 HPE 3.2TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91088-B21 HPE 6.4TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P87715-B21 HPE 1.6TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 Self-encrypting 7600 SSD
  • P87717-B21 HPE 3.2TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 Self-encrypting 7600 SSD
  • P85114-B21 HPE 1.6TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 SPDM 7600 SSD
  • P85117-B21 HPE 3.2TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 SPDM 7600 SSD
  • P85119-B21 HPE 6.4TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 SPDM 7600 SSD
  • P85731-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85733-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85735-B21 HPE 12.8TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin PQC27 CM9 SSD
Read Intensive – NVMe - EDSFF - Solid State Drives
  • P57799-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM PM1743 SSD
  • P57807-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM PM1743 SSD
  • P70392-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3S EC1 PS1010 SSD
  • P70395-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3S EC1 PS1010 SSD
  • P70397-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3S EC1 PS1010 SSD
  • P77269-B21 HPE 1.92TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 EDSFF SPDM PE1010 SSD
  • P77271-B21 HPE 3.84TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 EDSFF SPDM PE1010 SSD
  • P77275-B21 HPE 15.36TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 EDSFF SPDM PE1010 SSD
  • P91229-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91231-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91233-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91090-B21 HPE 1.92TB NVMe Gen5 Mainstream Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91092-B21 HPE 3.84TB NVMe Gen5 Mainstream Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91094-B21 HPE 7.68TB NVMe Gen5 Mainstream Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91096-B21 HPE 15.36TB NVMe Gen5 Mainstream Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P87719-B21 HPE 1.92TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 Self-encrypting 7600 SSD
  • P87721-B21 HPE 3.84TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 Self-encrypting 7600 SSD
  • P87723-B21 HPE 7.68TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 Self-encrypting 7600 SSD
  • P85121-B21 HPE 1.92TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 SPDM 7600 SSD
  • P85124-B21 HPE 3.84TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 SPDM 7600 SSD
  • P85126-B21 HPE 7.68TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 SPDM 7600 SSD
  • P85128-B21 HPE 15.36TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 SPDM 7600 SSD
  • P85739-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85741-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85743-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85745-B21 HPE 30.72TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin PQC27 CM9 SSD
Very Read Optimized – NVMe - EDSFF - Solid State Drives
HPE notes (2)
  • NVMe EDSFF drive can only be selected with 12EDSFF Drive Cage Kit (P72320-B21).
  • NVMe EDSFF drives are limited to 25°C maximum inlet temperature and system fans may operate at higher speed and higher acoustic level to maintain optimum system cooling condition while EDSFF is installed.
Memory5 parts

All memory on the ML350 Gen12 Memory page

Memory – for the Intel Xeon 6700P/6500P-series processor
HPE notes (7)
  • The maximum memory speed and capacity is a function of the memory type, memory configuration, and processor model.
  • The quantity of memory DIMMs selected per socket must be 1, 2, 4, 8, 12, or 16.
  • Mixing of different Rank memory is allowed only if max memory quantity is selected per processor (i.e. 16 memory for 1 processor and 32 memory for 2 Processors).
  • X4 and x8 memory cannot be mixed.
  • 64GB, 96GB, 128GB, 256GB memory cannot be mixed with any other capacity.
  • Redundant fan configuration is required for 256GB memory.
  • The -B21 memory SKUs shown in this document are to be used when ordering stand-alone memory only. For each -B21 SKU, there is a corresponding -F21 SKU which is to be used when configuring servers with integrated memory DIMMs.
Network adapters22 parts

All network adapters on the ML350 Gen12 Networking Adapters page

HPE notes (4)
  • Up to 2 OCP networking adapters are supported, OCP B slot is the default slot for OCP networking adapter.
  • WOL and shared NIC function are only supported in OCP B slot.
  • An OCP B Enablement Kit is required when installing OCP card in OCP B slot.
  • OCP A slot provides x8 PCIe 5.0 lanes from system board, additional OCP A Enablement Kit may require for x16 OCP NIC to install on OCP A slot.

Ethernet PCIe

1 Gigabit Ethernet adapters
10 Gigabit Ethernet adapters
10/25 Gigabit Ethernet adapters
100 Gigabit Ethernet adapters

Ethernet OCP Adapter

1 Gigabit Ethernet OCP adapters
10 Gigabit Ethernet OCP Adapters
10/25 Gigabit Ethernet OCP adapters
100 Gigabit Ethernet adapters

InfiniBand

HPE notes (5)
  • When AOC (Active Optical Cables) and processors TDP greater than 270W are selected, limited to 25°C maximum inlet temperature is supported with all drive cage combinations.
  • When AOC (Active Optical Cables) and processors TDP equal to or less than 270W are selected, limited to 30°C maximum inlet temperature is supported with up to 2x LFF and/or Tri-Mode SFF drive cage.
  • When DAC (Direct Attach Cables) is selected, limited to 30°C maximum inlet temperature is supported with all drive cage combinations.
  • InfiniBand controllers require PCIe x16 bandwidth. 2x16 Primary FIO Riser Kit (P48406-B21) or 2x16 Secondary Riser Kit (P47238-B21) is required.
  • Redundant Fan Kit (P47219-B21) is required.
  • P45641-H23 HPE InfiniBand NDR/Ethernet 400Gb 1-port OSFP PCIe5 x16 MCX75310AAS-NEAT Adapter
  • P65333-H21 HPE InfiniBand NDR200/Ethernet 200GbE 2-port QSFP112 PCIe5 x16 MCX755106AC-HEAT Adapter
Storage controllers8 parts

All storage controllers on the ML350 Gen12 Storage Controllers page

HPE notes (2)
  • OCP-type RAID (OROC) controller can only be supported on OCP A slot.
  • OCP enablement kit is not required for OROC controllers.

Tri-Mode RAID Controllers

External RAID Controllers

Drive cages and backplanes4 parts
HPE notes (3)
  • Supports up to 3 drive cages from following selections.
  • Mixing NVMe x4 drive cage and 12EDSFF drive cage is not allowed.
  • Supports mixing 8SFF x1, 4LFF drive cage with NVMe x4 or 12EDSFF drive cage.
  • P72318-B21 HPE ProLiant Compute ML350 Gen12 8SFF x1 Tri-Mode Drive Cage Kit
    HPE note

    Supports up to 8 SFF SAS/SATA/NVMe x1 drives in one drive cage, controller and cable kit are required.

  • P72357-B21 HPE ProLiant Compute ML350 Gen12 4LFF SAS/SATA Drive Cage Kit
    HPE note

    Supports up to 4 LFF SAS/SATA drives in one drive cage, controller and cable kit are required.

  • P72316-B21 HPE ProLiant Compute ML350 Gen12 8SFF x4 NVMe Drive Cage Kit
    HPE note

    Mixing x2 and x4 cable kits is not allowed. Mixing Direct Attach and Controller cable kits is not allowed. In direct attach mode, 2nd processor is required with (2) set of x4 drive cage and x4 cable kit. With MR932i-p. each set of x4 drive cage and x4 cable kit requires 1 MR932i-p controller. With x4 cable kit, Supports up to 2 drive cages for 16 NVMe drives. In direct attach mode, Single processor supports up to 2 sets of x4 drive cage and x2 cable kit and 2nd processor is required with Third set of x4 drive cage and x2 cable kit. MR932i-p controller supports up to 2 sets of x4 drive cage and x2 cable kit. With x2 cable kit, Supports up to 3 drive cages for 24 NVMe drives.

  • P72320-B21 HPE ProLiant Compute ML350 Gen12 12EDSFF x4 NVMe Drive Cage Kit
    HPE note

    Supports up to 1 drive cage with direct attach or PCIe controller cable kit for 12 EDSFF NVMe drives. Dual processors configuration is required with direct attach mode. Two MR932i-p controllers are required with PCIe controller cable kit (P77439-B21). Redundant Fan Kit (P47219-B21) and Second CPU Fan Kit (P47902-B21) are required. External Fan kit included in this drive cage kit to be installed in rear of chassis and covered rear of primary riser cage, results external connectivity is not allowed.

Riser cards3 parts
HPE note

The primary riser and secondary riser are interchangeable.

  • P48407-B21 HPE ProLiant Compute ML350 Gen11/Gen12 4x8 Secondary Riser Kit
    HPE note

    When this riser kit is selected, a secondary processor is required.

  • P47238-B21 HPE ProLiant Compute ML350 Gen11/Gen12 2x16 Secondary Riser Kit
    HPE note

    When this riser kit is selected, a secondary processor is required.

  • P79317-B21 HPE ProLiant Compute ML350 Gen12 2x8 Tertiary Riser Kit
    HPE note

    When this Riser Kit is selected, a second processor is required to support expansion card installation and 2 MCIO connectors from CPU2 will be used. Without Second processor, the PCIe slots from tertiary riser will not have function and only able to provide power source for internal LTO tape drive.

Power supplies5 parts

All power supplies on the ML350 Gen12 Power Supplies page

HPE notes (2)
  • Mixing 2 different power supplies is NOT supported.
  • Selection of two HPE Flex Slot power supplies provide 1+1 power redundancy.
Processors19 parts

All processors on the ML350 Gen12 Processors page

Processor Option Kits – Intel Xeon 6700/6500 Series Processors with Performance Core (P-core)

HPE notes (9)
  • Mixing of 2 different processor models is not supported.
  • Processor kits don’t include heat sink and fans.
  • Processors with TDP equal to or greater than 225W require Performance Heatsink (P72359-B21).
  • Processors with TDP equal to or greater than 300W require both Redundant Fan Kit (P47219-B21) and Second CPU Fan Kit (P47902-B21).
  • CTO server includes 3 fans as standard. Second CPU Fan Kit (P47902-B21) is required for 2 processors configuration as 4th fan.
  • All SKUs ship with processor only. Adequate fan and heatsink kits (standard or performance) must be selected.
  • 6400 MT/s maximum memory speed with 1DPC and 5200 MT/s maximum memory speed with 2DPC.
  • 128GB SGX Enclave unless otherwise noted.
  • Performance Heatsink (P72359-B21) is required unless otherwise noted.
Intel Xeon 6700P-series Processors
  • P73837-B21 Intel Xeon 6787P 2.0GHz 86-core 350W Processor for HPE
    HPE note

    Requires Redundant Fan Kit (P47219-B21) and Second CPU Fan Kit (P47902-B21). 512GB SGX Enclave.

  • P73834-B21 Intel Xeon 6767P 2.4GHz 64-core 350W Processor for HPE
    HPE note

    Requires Redundant Fan Kit (P47219-B21) and Second CPU Fan Kit (P47902-B21). 512GB SGX Enclave.

  • P73832-B21 Intel Xeon 6760P 2.2GHz 64-core 330W Processor for HPE
    HPE note

    Requires Redundant Fan Kit (P47219-B21) and Second CPU Fan Kit (P47902-B21).

  • P73831-B21 Intel Xeon 6747P 2.7GHz 48-core 330W Processor for HPE
    HPE note

    Requires Redundant Fan Kit (P47219-B21) and Second CPU Fan Kit (P47902-B21). 512GB SGX Enclave.

  • P81591-B21 Intel Xeon 6745P 3.1GHz 32-core 300W Processor for HPE
    HPE note

    Requires Redundant Fan Kit (P47219-B21) and Second CPU Fan Kit (P47902-B21). 512GB SGX Enclave.

  • P73829-B21 Intel Xeon 6740P 2.1GHz 48-core 270W Processor for HPE
  • P74576-B21 Intel Xeon 6737P 2.9GHz 32-core 270W Processor for HPE
    HPE note

    512GB SGX Enclave.

  • P74575-B21 Intel Xeon 6736P 2.0GHz 36-core 205W Processor for HPE
    HPE note

    Requires Standard Heatsink (P72358-B21). 512GB SGX Enclave.

  • P74573-B21 Intel Xeon 6730P 2.5GHz 32-core 250W Processor for HPE
    HPE note

    512GB SGX Enclave.

  • P87302-B21 Intel Xeon 6725P 3.7GHz 16-core 235W Processor for HPE
    HPE note

    512GB SGX Enclave.

Intel Xeon 6500P-series Processors
  • P74571-B21 Intel Xeon 6530P 2.3GHz 32-core 225W Processor for HPE
  • P74570-B21 Intel Xeon 6527P 3.0GHz 24-core 255W Processor for HPE
    HPE note

    512GB SGX Enclave.

  • P74568-B21 Intel Xeon 6520P 2.4GHz 24-core 210W Processor for HPE
    HPE note

    Requires Standard Heatsink (P72358-B21).

  • P74507-B21 Intel Xeon 6517P 3.2GHz 16-core 190W Processor for HPE
    HPE note

    Requires Standard Heatsink (P72358-B21). 512GB SGX Enclave.

  • P74506-B21 Intel Xeon 6515P 2.3GHz 16-core 150W Processor for HPE
    HPE note

    Requires Standard Heatsink (P72358-B21).

  • P74504-B21 Intel Xeon 6507P 3.5GHz 8-core 150W Processor for HPE
    HPE note

    Requires Standard Heatsink (P72358-B21). 512GB SGX Enclave.

  • P74503-B21 Intel Xeon 6505P 2.2GHz 12-core 150W Processor for HPE
    HPE note

    Requires Standard Heatsink (P72358-B21).

Heat Sinks

HPE note

Select heat sink that matching processor quantity.

  • P72358-B21 HPE ProLiant Compute ML350 Gen12 Standard Heat Sink Kit
    HPE note

    Processors with TDP less than 225W require Standard Heat Sink.

  • P72359-B21 HPE ProLiant Compute ML350 Gen12 Performance Heat Sink Kit
    HPE note

    Processors with TDP equal to or greater than 225W require Performance Heat Sink.

Cable kits20 parts
  • P47221-B21 HPE ProLiant ML350 12(8+4)-pin/16-pin Cable Kit for NVIDIA GPU
    HPE note

    This power Cable Kit (P47221-B21) is required for L40, L40S, RTX PRO 4500 Accelerator. Each power Cable Kit supports up to one accelerator.

Storage Controller Cables

  • P77436-B21 HPE ProLiant Compute ML350 Gen12 4LFF SAS/SATA OROC Box 3 Cable Kit
    HPE note

    This cable kit supports 1x 4LFF drive cages with HPE OCP-type RAID controller (OROC) at Box3.

  • P77435-B21 HPE ProLiant Compute ML350 Gen12 8LFF SAS/SATA OROC Cable Kit
    HPE note

    This cable kit supports 2x 4LFF drive cages with HPE OCP-type RAID controller (OROC) at Box2/3 or Box1/2.

  • P77432-B21 HPE ProLiant Compute ML350 Gen12 4LFF SAS/SATA PCIe Box 3 Cable Kit
    HPE note

    This cable kit supports 1x 4LFF drive cages with HPE stand-up PCIe storage controller at Box3.

  • P77431-B21 HPE ProLiant Compute ML350 Gen12 8LFF SAS/SATA PCIe Cable Kit
    HPE note

    This cable kit supports 2x 4LFF drive cages with HPE stand-up PCIe storage controller at Box2/3 or Box1/2.

  • P47235-B21 HPE ProLiant Compute ML350 Gen11/Gen12 8SFF x1 OROC Box 2/3 Cable Kit
    HPE note

    This cable kit supports 2x 8SFF drive cages with HPE OCP-type RAID controller (OROC) at Box2/3.

  • P77434-B21 HPE ProLiant Compute ML350 Gen12 8SFF x1 Tri-Mode PCIe Box 3 Cable Kit
    HPE note

    This cable kit supports 2x 8SFF drive cages with HPE stand-up PCIe storage controller at Box2/3.

  • P77433-B21 HPE ProLiant Compute ML350 Gen12 8SFF x1 Tri-Mode PCIe Box 1/2 Cable Kit
    HPE note

    This cable kit supports 2x 8SFF drive cages with HPE stand-up PCIe storage controller at Box1/2.

  • P72361-B21 HPE ProLiant Compute ML350 Gen12 8SFF x4 NVMe Direct Attach Cable Kit
    HPE note

    This cable kit supports 1x 8NVMe x4 Drive Cage Kit (P72316-B21) with x4 direct attached, up to 2 at Box 2/3.

  • P72363-B21 HPE ProLiant Compute ML350 Gen12 8SFF x2 NVMe Direct Attach Cable Kit
    HPE note

    This cable kit supports 1x 8NVMe x4 Drive Cage Kit (P72316-B21) with x2 direct attached, up to 3.

  • P72362-B21 HPE ProLiant Compute ML350 Gen12 12EDSFF x4 Direct Attach Cable Kit
    HPE note

    This cable kit supports 1x 12EDSFF x4 NVMe Drive Cage Kit (P72320-B21) with direct attached at Box 3.

  • P88370-B21 HPE ProLiant Compute ML350 Gen12 8SFF x4 NVMe PCIe Cable Kit
    HPE note

    This cable kit supports 1x 8NVMe x4 Drive Cage Kit (P72316-B21) with MR932i-p controller, up to 2 at Box 2/3.

  • P88371-B21 HPE ProLiant Compute ML350 Gen12 8SFF x2 NVMe PCIe Cable Kit
    HPE note

    This cable kit supports 1x 8NVMe x4 Drive Cage Kit (P72316-B21) with MR932i-p controller, up to 3.

  • P77439-B21 HPE ProLiant Compute ML350 Gen12 12EDSFF PCIe Cable Kit
    HPE note

    This cable kit supports 1x 12EDSFF x4 NVMe Drive Cage Kit (P72320-B21) with MR932i-p controller at Box 3.

OCP Cable Options

  • P72201-B21 HPE ProLiant Compute DL3XX/ML350 Gen12 CPU1 to Rear OCP SlotA x16 Cable Kit
    HPE note

    This cable kit supports x16 OCP NIC adapter on OCP A slot. CPU 1 MCIO connector will be occupied.

  • P72203-B21 HPE ProLiant Compute DL3XX/ML350 Gen12 CPU1 to Rear OCP SlotB x8 Cable Kit
    HPE note

    This cable kit supports x8 OCP NIC adapter on OCP B slot. CPU 1 MCIO connector will be occupied.

  • P72205-B21 HPE ProLiant Compute DL3XX/ML350 Gen12 CPU2 to Rear OCP SlotB x8 Cable Kit
    HPE note

    This cable kit supports x8 OCP NIC adapter on OCP B slot. 1x CPU 2 MCIO connector will be occupied.

  • P72207-B21 HPE ProLiant Compute DL3XX/ML350 Gen12 CPU2 to Rear OCP SlotB x16 Cable Kit
    HPE note

    This cable kit supports x16 OCP NIC adapter on OCP B slot. 2x CPU 2 MCIO connector will be occupied.

Internal LTO Support Kit

  • P77437-B21 HPE ProLiant Compute ML350 Gen12 Internal LTO PCIe Cable Kit
    HPE note

    Supporting cables to connect -p controller with internal LTO tape drive for data backup or archiving.

  • P77438-B21 HPE ProLiant Compute ML350 Gen12 Internal LTO OROC Cable Kit
    HPE note

    Supporting cables to connect -o controller with internal LTO tape drive for data backup or archiving.

Fibre Channel HBAs4 parts
Boot devices5 parts
HPE notes (2)
  • When NS204i-u is selected, Second CPU Fan Kit (P47902-B21), NS204i-u Front Enable Kit (P74252-B21) or NS204i-u Rear Enable Kit (P72360-B21) are required.
  • Without Redundant Fan Kit (P47219-B21), limited to 25°C maximum inlet temperature with 3 SFF/LFF Drive Cages selected with NS204i-u.
Smart Storage battery4 parts
HPE note

Above 260mm cable kits can’t be selected together.

  • P58199-B21 HPE ProLiant Compute ML350 Gen11/Gen12 Smart Storage Battery Cable Kit
    HPE note

    This cable kit is required when any of battery kit (P02377-B21, P01366-B21) is selected.

Optical drives4 parts
Security1 part
  • P47226-B21 HPE ProLiant Compute ML Gen11/Gen12 Intrusion Cable Kit
Rack options1 part
  • P47394-B21 HPE ProLiant Compute ML Gen11/Gen12 Tower to Rack Conversion Kit
    HPE note

    Easy install rack rail tray which takes up 1U height in a standard rack facility. This kit is supported in both ML350 Gen11/Gen12 and ML110 Gen11 for tower to rack conversion. This kit includes CMA and is shipped as standard. This kit is not factory integrable option and only can be shipped with standalone package.

Management hardware1 part
  • P55062-B21 HPE ProLiant Compute ML350 Gen11/Gen12 Serial Port Cable Kit
Fan kits3 parts
  • P47902-B21 HPE ProLiant Compute ML350 Gen11/Gen12 Second CPU Fan Kit
    HPE note

    When either secondary processor, Redundant Fan Kit, NS204i-u V2, Tertiary Riser Kit selected, this Fan Kit is required.

  • P47219-B21 HPE ProLiant Compute ML350 Gen11/Gen12 Redundant Fan Kit
    HPE note

    Processors with TDP equal to or greater than 300W require this Fan Kit. When either EDSFF, SAS4 24G Mixed Use SSD drive, 256G memory, 200Gb or faster Ethernet/InfiniBand, GPU selected, this fan kit is required. When Redundant Fan Kit is selected, the Second CPU Fan Kit (P47902-B21) needs to be selected together.

  • P47220-B21 HPE ProLiant Compute ML350 Gen11/Gen12 External GPU Fan Kit
    HPE note

    With External GPU fan kit installed, the rear side of riser cage will be covered, and no connectivity allowed with Primary/ Secondary riser cage. Up to 2 External fan kits supported. External GPU fan kit provides advanced cooling in heavier configurations and allows the system to run with higher inlet temperature. This fan kit is already included in 12EDSFF Drive Cage Kit (P72320-B21) with quantity 1.

GPUs5 parts
HPE notes (4)
  • System memory is recommended to be 2 times larger than the memory with accelerator card.
  • Mixing different accelerators is not supported.
  • Redundant Fan Kit (P47219-B21) and Second CPU Fan Kit (P47902-B21) are required for all GPU accelerators.
  • GPU are all required x16 bandwidth unless otherwise noted. Therefore, 2x16 Primary FIO Riser Kit (P48406-B21) or 2x16 Secondary Riser Kit (P47238-B21) is required to support up to 2 GPUs with each riser kit.
  • S0K90C NVIDIA L40 48GB PCIe Accelerator for HPE
    HPE note

    GPU Power Cable Kit (P47221-B21) is required and supports up to 1 GPU with each cable kit. External GPU Fan Kit (P47220-B21) is recommended to provide advanced cooling and results DisplayPorts can’t be connected and covered by the fan kit. Without External GPU Fan Kit installed, maximum inlet temperature is limited to 23°C with limited configuration: Up to 2 GPUs, up to 64GB memory, up to TDP 195W processor(s) and one Drive Cage (8SFF/4LFF) only.

  • S2L70C NVIDIA L40S 48GB PCIe Accelerator
    HPE note

    Limited to support L40S to be installed on Slot 2 and/or Slot 6 with x16 Riser Cage. GPU Power Cable Kit (P47221-B21) is required and supports up to 1 GPU with each cable kit. External GPU Fan Kit (P47220-B21) is recommended for this accelerator to provide advanced cooling and results DisplayPorts can’t be connected and covered by the fan kit. Without External GPU Fan Kit installed, maximum inlet temperature is limited to 23°C with configuration: 2x Processor with TDP equal to or less than 190W, 1x GPU on Secondary Riser, up to 64GB memory, with only one Drive Cage.

  • S6W30C NVIDIA RTX PRO 4500 Blackwell Server Edition 32GB PCIe Accelerator for HPE
    HPE note

    GPU Power Cable Kit (P47221-B21) is required and supports up to 1 GPU with each cable kit. External GPU Fan Kit (P47220-B21) is recommended to provide advanced cooling and results Display Ports can’t be connected and covered by the fan kit. Without External GPU Fan Kit installed, maximum inlet temperature is limited to 23°C with limited configuration: Up to 2 GPUs, up to 64GB memory, with TDP equal to or less than 190W, with only one Drive Cage.

  • S5T74C NVIDIA RTX A1000 8GB PCIe Accelerator for HPE
    HPE note

    This GPU supports x8 bandwidth, x16 Riser Cage is not required. Support up to 8 GPU in 4x8 Primary and Secondary Riser cage.

  • S0K89C NVIDIA L4 24GB PCIe Accelerator for HPE
    HPE note

    External GPU Fan Kit (P47220-B21) is required to provide advanced cooling with this GPU.

Tape backup8 parts
HPE notes (3)
  • When internal LTO tape drive is configured, Tertiary Riser Kit (P79317-B21) and LTO cable kit (P77437-B21 or P77438-B21) are required. One available port from MR216i-o/p or MR408i-o/p storage controller is required to connect to LTO tape drive.
  • Up to 1 internal LTO tape drive is supported in Box1 and Media Bay location.
  • Required to change Thermal Configuration to Increased Cooling mode in BIOS/Platform Configuration (RBSU) menu and system fans may operate at higher speed and higher acoustic level.
  • BC040A HPE StoreEver LTO-9 Ultrium 45000 Internal Tape Drive
  • BC022A HPE StoreEver LTO-8 Ultrium 30750 Internal Tape Drive
  • BC024A HPE StoreEver LTO-8 Ultrium 30750 TAA-compliant SAS Internal Tape Drive

HPE External Tape Drives

HPE note

External controllers and cables are required.

  • BC023A HPE StoreEver LTO-8 Ultrium 30750 External Tape Drive
  • BC042A HPE StoreEver LTO-9 Ultrium 45000 External Tape Drive

HPE Tape Drives Cartridge

  • Q2079A HPE LTO-9 Ultrium 45TB RW Data Cartridge
  • Q2078A HPE LTO-8 Ultrium 30TB RW Data Cartridge
  • C7977A HPE LTO-7 Ultrium 15TB RW Data Cartridge
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