HPE ProLiant ML350 Gen12 Memory
The ML350 Gen12 has 32 DIMM slots, 16 per processor, and takes one kit family: HPE DDR5-6400 EC8 RDIMMs from 32GB to 256GB. Every kit on this page fits every ML350 Gen12, so the only decisions are how many processors you have and how much memory you want. Maximum is 8TB with two processors and 256GB in every slot.
- 32 DIMM slots, 16 per processor
- DDR5-6400 EC8 RDIMM, 32GB to 256GB
- Up to 8TB
- 8 channels per processor
Specifications match the HPE ProLiant ML350 Gen12 QuickSpecs. LRDIMM, UDIMM, non-ECC and DDR4 are not supported.
How many DIMMs per processor, and what speed you get
Each processor has 8 memory channels with 2 slots per channel. One DIMM in every channel is the full-speed configuration. Filling the second slot doubles capacity and steps the speed down.
| DIMMs per processor | Channels used | Speed | When to choose it |
|---|---|---|---|
| 8 | 8 of 8, one DIMM each | 6400 MT/s | The configuration to aim for: full bandwidth, and 8 slots per processor stay free for a later upgrade. |
| 16 | 8 of 8, two DIMMs each | 5200 MT/s | Maximum capacity. 5200 MT/s. |
| 4 | 4 of 8 | 6400 MT/s | Budget builds. Full speed on the channels used, half the bandwidth of 8 DIMMs. |
| 1 or 2 | 1 or 2 of 8 | 6400 MT/s | Supported for minimal configurations; not recommended for production workloads. |
The speed the server delivers is the lowest of the processor rating, the population and the slowest installed DIMM. HPE lists no 16GB kit for this server. HPE: "The quantity of memory DIMMs selected per socket must be 1, 2, 4, 8, 12, or 16."; the picker uses those counts.
Three rules that avoid a return
1 Populate both processors identically
Whatever you install on processor 1, install the same on processor 2. Buy an even number of DIMMs, and keep every DIMM in a bank the same capacity and rank.
2 Buy -B21, not -F21
Both suffixes describe the same module, but -F21 is sold only inside a factory-built server. The -B21 kits on this page are the ones you can buy and install yourself.
3 Match what is already installed
Adding to existing memory? Read the HPE part number on the DIMM label and buy that number. HPE does not allow x4 and x8 DIMMs to be mixed, and the 64GB, 96GB, 128GB and 256GB kits cannot be mixed with any other capacity in this server, so stay with one capacity.
ML350 Gen12 memory questions
How much memory does the HPE ProLiant ML350 Gen12 support?
Up to 8TB with two processors: 32 slots with 256GB DDR5-6400 RDIMMs in every one. With one processor only its 16 slots are usable, so 4TB. HPE requires the redundant fan configuration for 256GB DIMMs, and the 16GB DIMM supports one DIMM per channel only.
What type of memory does the ML350 Gen12 use?
HPE DDR5-6400 EC8 registered DIMMs (RDIMMs) in 32GB, 64GB, 96GB, 128GB and 256GB capacities. LRDIMM, UDIMM, non-ECC and DDR4 memory are not supported.
What speed will the memory run at?
6400 MT/s with one DIMM per channel (up to 8 per processor). With both slots of a channel filled, 5200 MT/s.
Can I use DL380 Gen12 memory in a ML350 Gen12?
Yes. Both servers list the same HPE DDR5-6400 EC8 RDIMM family in their QuickSpecs, though the ML350 Gen12 list starts at 32GB. Match the HPE part number rather than buying generic DDR5.
Do the DIMMs have to be installed in matched sets?
In practice, yes. Install an even number, keep both processors populated identically, and use the same capacity and rank within a bank. The picker above only suggests configurations that follow these rules.
Is this genuine HPE memory, and what is the warranty?
Yes. Every kit is a genuine HPE part, tested or factory sealed, and covered by our 5-year memory warranty. Most orders ship the same business day.
All HPE ProLiant ML350 Gen12 Memory kits
| Part number | Capacity | Type | Speed | Price | Availability | Add to cart |
|---|---|---|---|---|---|---|
 P69728-B21P69728-B21 HPE 64GB (1x64GB) Dual Rank x4 DDR5-6400 CAS-46-45-45 EC8 Registered Smart Memory Kit |
$3,785.00 | In stock | ||||
 P69727-B21P69727-B21 HPE 32GB (1x32GB) Dual Rank x8 DDR5-6400 CAS-46-45-45 EC8 Registered Smart Memory Kit |
$2,838.00 | In stock | ||||
 P69729-B21P69729-B21 HPE 96GB (1x96GB) Dual Rank x4 DDR5-6400 CAS-46-45-45 EC8 Registered Smart Memory Kit |
$5,275.00 | In stock | ||||
 P69730-B21P69730-B21 HPE 128GB (1x128GB) Dual Rank x4 DDR5-6400 CAS-46-45-45 EC8 Registered Smart Memory Kit |
Price on request | Out of stock | ||||
 P73447-B21P73447-B21 HPE 256GB (1x256GB) Quad Rank x4 DDR5-6400 CAS-60-52-52 EC8 Registered 3DS Smart Memory Kit |
Price on request | Out of stock |
Prices shown are today's store prices. Volume pricing is available on every kit; ask for a quote for ten or more.
Buying for several servers, or a different model?
Send us the server models and the memory you want in each and we will quote every kit by the next business day. Live chat is the fastest way to reach us.
