This item, P74503-B21, is the HPE option part number for the product described as Intel Xeon 6505P 2.2GHz 12‑core 150W Processor for HPE. Further details below.
The Intel Xeon 6505P (P74503-B21) brings 12 performance cores at 2.2GHz, 48MB of L3 cache, and a 150W TDP to HPE ProLiant Compute Gen12 platforms. Built on the Intel Xeon 6500P-series P-core architecture with an LCC die, it pairs high per-core throughput with DDR5 memory at up to 6400 MT/s and four UPI links at 24 GT/s, so data moves quickly between sockets, memory, and I/O for virtualization, database, and general-purpose enterprise workloads. A 128GB SGX enclave size adds hardware-backed protection for sensitive data in memory.
This genuine HPE option kit is validated for HPE ProLiant Compute DL320, DL340, DL340e, DL360, DL380, DL380a, and ML350 Gen12 servers, the HPE Synergy 480 Gen12 Compute Module, and Nutanix HPE ProLiant DL360/DL380 Gen12 nodes. In the ML350 Gen12, the Standard Heatsink (P72358-B21) is required. Backed by Global One Technology's expert support, fast shipping, and quantity discounts, P74503-B21 is a straightforward way to deploy or scale Gen12 compute with confidence.
HPE Option Part #: P74503-B21
PRODUCT SPECIFICATIONS FOR P74503-B21:
- SKU / Part number: P74503-B21
- Processor model: Intel Xeon 6505P
- CPU frequency: 2.2 GHz
- Cores: 12
- L3 cache: 48 MB
- TDP: 150W
- UPI links (24 GT/s): 4
- DDR5 Memory Speed: 6400 MT/s
- SGX Enclave size: 128 GB
- Processor series: Intel Xeon 6500P-series (P-core)
- Die type: LCC
- Required heatsink (ML350 Gen12): Requires Standard Heatsink (P72358-B21)
COMPATIBLE WITH:
PROLIANT HPE SERIES
PROLIANT NUTANIX SERIES
PROLIANT DL SERIES
PROLIANT ML SERIES
** This list may not be complete. Contact us via Live Chat if you have any questions about compatibility.
FREQUENTLY ASKED QUESTIONS FOR P74503-B21:
- Which HPE servers support the P74503-B21 processor?
P74503-B21 is supported in HPE ProLiant Compute DL320, DL340, DL340e, DL360, DL380, DL380a, and ML350 Gen12 servers, the HPE Synergy 480 Gen12 Compute Module, and Nutanix HPE ProLiant DL360 Gen12 and DL380 Gen12 systems. - Does P74503-B21 require a specific heatsink?
Yes. For installation in the HPE ProLiant Compute ML350 Gen12, P74503-B21 requires the Standard Heatsink, part number P72358-B21. - What are the key specifications of P74503-B21?
P74503-B21 is an Intel Xeon 6505P from the Xeon 6500P-series (P-core, LCC die) with 12 cores at 2.2GHz, 48MB L3 cache, a 150W TDP, four UPI links at 24 GT/s, DDR5 memory support up to 6400 MT/s, and a 128GB SGX enclave size.
Last Updated: 2026-10-08
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This product is warrantied against hardware failure for a period of 1 Year from the date of purchase. Before making a purchase, please take a moment to review our return policy below.
Returns
It is the customer's responsibility to verify compatibility with their machine(s) before placing an order. If an item is ordered by mistake, it can be returned for refund, minus a 25% restocking fee, within 5 business days of receipt. The cost of freight is not refundable.
Please be aware that factory-sealed equipment can only be returned if it remains unopened.
Defective Products
If you have received a defective part and your machine is still within the HPE warranty period, please initiate a warranty exchange by visiting the HPE Enterprise Support Center. Be sure to have the serial numbers of the defective drive and your server/storage array handy.
In case your hardware becomes defective during the Global One warranty period, but the HPE warranty has expired, you can return the product to us for a working replacement. You are responsible for the shipment of returned merchandise. However, we will cover the expense of Ground /Economy shipment for the replacement item(s).
Requesting an RMA
To initiate a return or warranty claim, please complete and submit the RMA Request Form.
