HPE ProLiant ML350 Gen12 Parts

The HPE ProLiant ML350 Gen12 is a 4U tower built around one or two Intel Xeon 6700P/6500P-series processors, 32 DDR5 DIMM slots and PCIe Gen5 I/O, with room for up to three front drive cages. It converts to a 5U rack unit with the tower-to-rack kit. Every part below is genuine HPE, available new and refurbished, and tested for compatibility before it ships. Live pricing for each part number appears in the tables further down this page.

ML350 Gen12 Platform at a Glance

• Form factor: 4U tower, 46.2 × 71.2 × 17.4 cm; 5U in a rack with the HPE ML Gen11/Gen12 Tower to Rack Conversion Kit, a 1U rail tray with cable management arm
• Processors: one or two Intel Xeon 6700P/6500P-series P-core processors, from the 8-core 6507P to the 86-core 6787P, 150W to 350W, 88 PCIe 5.0 lanes each
• Memory: 32 DDR5 DIMM slots — 16 per processor, 8 channels, 2 DIMMs per channel — HPE DDR5 Smart Memory RDIMMs to 6400 MT/s, documented maximum 8TB
• Drive bays: no cage as standard; up to three from 8SFF x1 Tri-Mode (SAS/SATA/NVMe), 4LFF SAS/SATA, 8SFF x4 NVMe and 12EDSFF x4 NVMe, for up to 24 SFF, 12 LFF, or 12 EDSFF plus 8 SFF plus 4 LFF drives
• Storage controllers: HPE MR216i, MR408i and MR416i Gen11 in OCP (-o) or PCIe (-p) form, the MR932i-p x32 PCIe Gen5 NVMe controller, the E208e-p external and the NS204i-u v2 boot device
• Expansion: four PCIe Gen5 x8 slots on the standard primary riser, optional secondary (4x8 or 2x16) and tertiary (2x8) risers, two OCP 3.0 slots; slots 5 to 10 need the second processor
• Networking: no embedded ports — OCP 3.0 or PCIe adapters from 1GbE to 100GbE, NDR InfiniBand, 32Gb and 64Gb Fibre Channel HBAs; dedicated 1Gb iLO port standard
• Power and cooling: up to two Flex Slot hot-plug power supplies from 800W to 2200W for 1+1 redundancy; 3 fans standard, up to 8 with the Second CPU and Redundant fan kits
• Accelerators and management: NVIDIA L40, L40S, RTX PRO 4500, RTX A1000 and L4; HPE iLO 7 with a front iLO service port

The second processor unlocks half of this tower. PCIe slots 5 to 10, the other 16 DIMM slots and the 2x16 secondary riser are all wired to CPU 2 — and every x16 network adapter, GPU and InfiniBand card on this page needs that riser. A single-processor ML350 Gen12 has four x8 slots, 16 DIMM slots and two OCP slots, and the Second CPU Fan Kit is the first part on any upgrade path out of it.

Specifications on this page are taken from the HPE QuickSpecs for this server, HPE ProLiant Compute ML350 Gen12 QuickSpecs, Version 16.

Which ML350 Gen12 drive cage do you need?

Tri-Mode and LFF cages mix freely and can sit beside an NVMe x4 or EDSFF cage; the NVMe x4 and 12EDSFF cages cannot share a chassis. Beyond storage, the second processor unlocks PCIe slots 5 to 10, the other 16 DIMM slots and the 2x16 secondary riser that every x16 adapter, GPU and InfiniBand card needs.

Shop ML350 Gen12 Parts by Category

• ML350 Gen12 memory — DDR5-6400 Registered Smart Memory kits, 32GB to 256GB
• ML350 Gen12 drives — SFF and LFF hard drives, SAS, SATA and U.3 NVMe SSDs, E3.S EDSFF NVMe
• ML350 Gen12 storage controllers — MR216i, MR408i, MR416i, MR932i-p and the E208e-p
• ML350 Gen12 networking adapters — OCP 3.0 and PCIe adapters, 1GbE to 100GbE, NDR InfiniBand
• ML350 Gen12 power supplies — Flex Slot units from 800W to 2200W, including -48VDC
• ML350 Gen12 processors — Intel Xeon 6700P and 6500P-series kits and heat sinks

Drive cages, cable kits, fan kits, risers, GPUs, Fibre Channel HBAs, boot devices, cache batteries, optical and LTO tape drives and the tower-to-rack kit are listed on this page below. We also stock HPE ProLiant ML350 Gen11 parts, the rest of the range under HPE ProLiant ML tower server parts, and every model under HPE parts by server model.

ML350 Gen12 Parts FAQ

Is the HPE ProLiant ML350 Gen12 a tower or a rack server?
A 4U tower. HPE lists a Tower to Rack Conversion Kit for the ML Gen11/Gen12 chassis, a 1U rail tray with cable management arm, and states that the system takes 5U of space in a standard rack once converted.

How many drives does the ML350 Gen12 hold?
Up to 24 SFF drives with three 8SFF cages, 12 LFF drives with three 4LFF cages, or 12 EDSFF plus 8 SFF plus 4 LFF with one cage of each. No drive cage is included as standard; each is an option kit that also needs a controller and cable kit.

What processors does the ML350 Gen12 use?
One or two Intel Xeon 6700P or 6500P-series processors with Performance cores, from the 8-core 6507P to the 86-core 6787P. Two processors must be the same model, and kits ship without heat sinks.

How much memory can the ML350 Gen12 take?
8TB, which HPE documents as 32 x 256GB RDIMMs at 5200 MT/s with two DIMMs per channel. The server has 32 DDR5 slots, 16 per processor, so a single-processor system has 16 slots available.

Does the ML350 Gen12 have built-in network ports?
No. HPE lists the network ports as none, with a choice of OCP 3.0 or stand-up PCIe adapter. Configure-to-order servers default to the Broadcom BCM5719 1Gb 4-port BASE-T OCP3 adapter, and a dedicated 1Gb iLO management port is standard.

Which upgrades need extra fan kits?
A second processor needs the Second CPU Fan Kit. Processors of 300W and above, GPUs, EDSFF drives, 256GB DIMMs, 24G SAS Mixed Use SSDs and 200Gb or faster adapters need the Redundant Fan Kit as well, which HPE requires to be fitted together with the Second CPU Fan Kit.

✅ Looking for a specific ML350 Gen12 part? Browse our full selection below.

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