HPE ProLiant ML350 Gen11 Networking Adapters

The ML350 Gen11 takes network adapters in its two OCP 3.0 slots and in up to 10 PCIe 5.0 slots on three risers, of which slots 5 to 10 need the second processor. No embedded network ports; networking comes from an OCP adapter or a stand-up card. HPE's QuickSpecs list 20 network adapters (Ethernet) for it.

  • 20 adapters
  • 1GbE to 100GbE
  • New and refurbished
  • Tested or factory sealed

From the HPE ProLiant ML350 Gen11 QuickSpecs (a50004308enw, version 48, 05-October-2026).

Slot map

Where each adapter goes in an ML350 Gen11

OCP 3.0
Two OCP 3.0 slots: slot 14 (OCP 1) for an OCP RAID controller or NIC, with x8 PCIe 5.0 lanes from the system board, and slot 15 (OCP 2) for a NIC, the default slot for the networking OCP3 adapter pp. 4, 50
Built-in ports
None p. 16
Primary riser
Slots 1–4: PCIe 5.0 x8, x8, x8, x8. On processor 1. + 1 other riser HPE lists for this position pp. 4, 12
Secondary riser
Slots 5–8: PCIe 5.0 x8, x8, x8, x8. Needs processor 2. + 1 other riser HPE lists for this position pp. 12, 37
Tertiary riser
Slots 9–10: PCIe 5.0 x8, x8. Needs processor 2. pp. 13, 38
HPE's words for each line
  • OCP 3.0 “Slot 14 OCP 1 (Optional for OROC/NIC adapter)” (page 4) “Slot 15 OCP 2 (Optional for NIC adapter)” (page 4) “Maximum of two OCP adapters are supported, the Networking OCP3 adapter uses Slot 15 (OCP 2 slot) by default.” (page 50) “Slot 14 OCP1 slot provides x8 PCIe 5.0 lanes from system board” (page 50)
  • Built-in ports “Network Ports None. Choice of OCP or stand-up card” (page 16)
  • Primary riser “Default with 4x8 Primary Riser Kit provides 4 slots with PCIe Gen5 x8 on Slot1-4.” (page 12) “1 CPU 1 PCIe 5.0 X8 X16 Full-height, full-length slot” (page 12) “4 CPU 1 PCIe 5.0 X8 X16 Full-height, full-length slot” (page 12) “PCIe Slots 1-4 (Primary riser)” (page 4) “There are two Primary riser configurations:” (page 12)
  • Secondary riser “4x8 Secondary Riser Kit provides 4 slots with PCIe Gen5 x8 on Slot5-8.” (page 12) “5 CPU 2 PCIe 5.0 X8 X16 Full-height, full-length slot” (page 12) “8 CPU 2 PCIe 5.0 X8 X16 Full-height, full-length slot” (page 12) “HPE ProLiant Compute ML350 Gen11/Gen12 4x8 Secondary Riser Kit P48407-B21” (page 37) “Notes: When this Riser Kit is selected, second processor is required.” (page 37) “There are two Secondary riser configurations as options:” (page 12)
  • Tertiary riser “2x8 Tertiary Riser Kit provides 2 slots with PCIe Gen5 x8 on Slot9 & 10.” (page 13) “9 CPU 2 PCIe 5.0 X8 X16 Half-height, Half-length slot” (page 13) “10 CPU 2 PCIe 5.0 X8 X16 Half-height, Half-length slot” (page 13) “HPE ProLiant ML350 Gen11 2x8 Tertiary Riser Kit P49693-B21” (page 38) “When this Riser Kit is selected, second processor is required to support expansion card installation and 2 MCIO connectors from CPU2 will be used. Without Second processor, the PCIe slots from tertiary riser will not have function and only can provide power source for internal LTO tape drive.” (page 38)

From the HPE ProLiant ML350 Gen11 QuickSpecs (a50004308enw, version 48, 05-October-2026).

All ML350 Gen11 network adapters

The network adapters HPE's QuickSpecs list for the ML350 Gen11, grouped by slot and type. In each group the adapters in stock come first, then the ones our customers order most.

OCP 3.0 or PCIe on the ML350 Gen11?

OCP 3.0PCIe adapter
How manyTwo OCP 3.0 slots: slot 14 (OCP 1) for an OCP RAID controller or NIC, with x8 PCIe 5.0 lanes from the system board, and slot 15 (OCP 2) for a NIC, the default slot for the networking OCP3 adapter.Up to 10 PCIe 5.0 slots on three risers
What HPE has listed1GbE to 100GbE Ethernet1GbE to 100GbE Ethernet
Slot rulesAn OCP RAID controller (OROC) can only go in slot 14 (OCP 1), so it shares that slot with OCP NICs; on the 8SFF base model P53566-291 slot 14 holds the MR408i-o and slot 15 the OCP3 NIC, so both OCP slots are taken.Slots 5 to 10 need the second processor.
How to tell from the nameOCP3 in the nameNo OCP3 in the name

How to choose an ML350 Gen11 network adapter

Rule 1

Decide the OCP 3.0 adapter first

An OCP RAID controller (OROC) can only go in slot 14 (OCP 1), so it shares that slot with OCP NICs; on the 8SFF base model P53566-291 slot 14 holds the MR408i-o and slot 15 the OCP3 NIC, so both OCP slots are taken.

HPE: “OCP-type RAID (OROC) controller is only supported on Slot 14 OCP 1.” (page 43)

Rule 2

Match the cabling to the switch

DAC cables or fiber transceivers and cables are bought separately.

HPE: “Direct Attach Cable (DAC) for copper environments or fiber transceivers and cables for fiber-optic environments must be purchased separately.” (page 50)

Rule 3

Count the processors

Slots 5 to 10 need the second processor.

HPE: “Notes: When this Riser Kit is selected, second processor is required.” (page 37)

Rule 4

Check the cooling

Networking cards of 100Gb or more may run the fans faster and louder, even at idle.

HPE: “High performance networking card is equaled or greater than 100Gb that may cause the fans to operate at higher speed and higher acoustic level to maintain optimum system cooling when system at idle status.” (page 50)

ML350 Gen11 adapter questions

How many network adapters can an ML350 Gen11 take?

The ML350 Gen11 takes network adapters in its two OCP 3.0 slots and in up to 10 PCIe 5.0 slots on three risers, of which slots 5 to 10 need the second processor. Four PCIe Gen5 slots in the primary riser as standard; up to ten (slots 1 to 10) with the secondary and tertiary risers and a second processor. An OCP RAID controller (OROC) can only go in slot 14 (OCP 1), so it shares that slot with OCP NICs; on the 8SFF base model P53566-291 slot 14 holds the MR408i-o and slot 15 the OCP3 NIC, so both OCP slots are taken.

Does the ML350 Gen11 have network ports built in?

No embedded network ports; networking comes from an OCP adapter or a stand-up card. CTO servers are configured with an OCP networking adapter and/or PCIe stand-up cards, with the Broadcom BCM5719 1Gb 4-port BASE-T OCP3 Adapter P51181-B21 selected by default; the Base Models table lists that adapter, in slot 15 (OCP 2).

Are cables or transceivers included?

DAC cables or fiber transceivers and cables are bought separately. HPE: “Direct Attach Cable (DAC) for copper environments or fiber transceivers and cables for fiber-optic environments must be purchased separately.” (page 50).

Do I need the second processor for more adapters?

Slots 5 to 10 need the second processor. Slots 1 to 4 run from processor 1. HPE: “Notes: When this Riser Kit is selected, second processor is required.” (page 37).

What does “Listed in QuickSpecs version 48” mean?

It means the adapter is in version 48 of HPE's QuickSpecs for the ML350 Gen11, the edition this page is built from.

What if the adapter I need is out of stock?

Out of stock today does not mean unavailable: we can often source this part. Add it to a quote request and we reply with current pricing and availability. Every message, quotes included, is answered within 24 hours.

More for the ML350 Gen11

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Most ordered for the ML350 Gen11

The adapters on this page our customers order most, for any server. Each card shows only while the store has it in stock.

OCP 3.0 adapters

9 adapters

Two OCP 3.0 slots: slot 14 (OCP 1) for an OCP RAID controller or NIC, with x8 PCIe 5.0 lanes from the system board, and slot 15 (OCP 2) for a NIC, the default slot for the networking OCP3 adapter.

PCIe Ethernet adapters

11 adapters

Stand-up cards for the PCIe slots.

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