HPE ProLiant DL365 Gen10 Plus Drives

The HPE ProLiant DL365 Gen10 Plus takes 2.5-inch SFF drives on HPE's Basic Carrier (BC): eight in the front, plus two in the optional media bay. They can be SAS, SATA or NVMe (U.3 and U.2), depending on the backplane. A Smart Array controller runs SAS and SATA, a tri-mode controller adds NVMe, and the embedded controller runs SATA drives direct attached. HPE also lists M.2 SSDs: SATA on the M.2 enablement kit, and NVMe on the NS204i-r riser.

  • Up to 10 SFF drives: 8 front, 2 in the media bay
  • Up to 10 NVMe drives with NVMe backplanes
  • SAS 24G and 12G, SATA 6G, NVMe Gen4 U.3 and U.2
  • One 8SFF chassis; no rear drive cages
  • NS204i-p boot device or NS204i-r M.2 riser

Bays, carriers and counts on this page are from HPE's QuickSpecs for the DL365 Gen10 Plus, document a50002558enw, Version 30 (July 28, 2025).

Which drives fit the DL365 Gen10 Plus

Every bay takes 2.5-inch SFF drives on the Basic Carrier (BC); the backplane and controller set the interface. HPE's maximum counts:

BaysDrive carrierInterfacesMost drives
SFF, front8SFF chassisBasic Carrier (BC)SAS/SATA backplane: SAS and SATA on a Smart Array or tri-mode controller, or SATA direct attached. x4 U.3 backplane: SAS, SATA and U.3 NVMe on a tri-mode controller, or U.3 NVMe direct attached. x4 U.2 backplane: U.2 NVMe8
SFF, media bay2SFF kitBasic Carrier (BC)SAS/SATA, U.3 or U.2 kitU.3 and U.2 backplane kits cannot be mixed2Not with an optical drive
M.2Universal SATA 6G AIC HHHL M.2 SSD Enablement Kit (878783-B21); NS204i-r riser (P26463-B21)SATA 6G on the kit; NVMe on the NS204i-r riser2 NVMe M.2 on the riserHPE lists P40513-B21 and P69543-B21 for the riser
BootHPE NS204i-pNVMe, PCIe3HPE lists one model, P12965-B21Slot 1 of the primary riser only
Optical9.5mm SATA DVD-ROM or DVD-RW; HPE Mobile USB DVD-RWSATA; the USB DVD-RW uses USB 3.0 ports onlyIn the media bay of the 8SFF CTO serverNot with a 2SFF drive cage or the M.2 kit (878783-B21)

Which backplane? How to tell

  1. Count the front bays. Every DL365 Gen10 Plus has eight 2.5-inch SFF bays. Two more in the media bay mean a 2SFF drive kit; an optical drive there means no 2SFF kit.
  2. Match the backplane kit. P38579-B21 is the 8SFF SAS/SATA backplane, P26429-B21 the 8SFF x4 tri-mode U.3 and P26433-B21 the 8SFF x4 NVMe U.2. In the media bay, P38580-B21 is 2SFF SAS/SATA, P38581-B21 2SFF U.3 and P38582-B21 2SFF U.2.
  3. Check the controller. An MR216i, MR416i, SR416i or SR932i is tri-mode; a Smart Array E208i, P408i or P816i runs SAS and SATA. With neither, SATA drives run direct attached on the embedded controller.
  • P38578-B218SFF CTO
  • P43251-B218SFF CTO (TAA)

Three rules before you order

Basic Carrier SFF only

HPE lists only Basic Carrier (BC) drives for the DL365 Gen10 Plus's SFF bays. It is an 8SFF server: HPE offers no LFF model and no rear drive cages.

The backplane and controller set the interface

The SAS/SATA backplanes take SAS and SATA on a Smart Array or tri-mode controller, or SATA direct attached. NVMe needs the x4 U.3 or U.2 backplanes, on a tri-mode controller or HPE's NVMe Direct FIO bundle; SR100i NVMe RAID does not support U.2 drives.

Plan the media bay and fans

A 2SFF drive kit needs an 8SFF drive cage, rules out the optical drive, and is not supported with the EPYC 7473X, 7573X or 7773X processors; U.3 and U.2 backplane kits cannot be mixed. HPE says performance fan kits should be required with NVMe or SAS4 drives.

DL365 Gen10 Plus drives FAQ

What drives fit the HPE ProLiant DL365 Gen10 Plus?

2.5-inch SFF drives on HPE's Basic Carrier (BC) in SAS, SATA or NVMe (U.3 and U.2): eight in the front and two in the optional media bay. HPE also lists SATA M.2 SSDs on a PCIe M.2 kit and NVMe M.2 SSDs for the NS204i-r riser. The backplane and controller decide which interfaces work.

Do drives from a DL365 Gen11 fit the DL365 Gen10 Plus?

HPE lists Basic Carrier (BC) SFF drives for both, and some part numbers, such as P28352-B21 and P40498-B21, are on both lists. Check that the part number is on this page.

Does the DL365 Gen10 Plus support NVMe drives?

Yes. With the x4 tri-mode U.3 or x4 NVMe U.2 backplane, the 8 front bays take NVMe drives, and a U.3 or U.2 2SFF kit adds two in the media bay, for 10 in all. They run on a tri-mode controller or HPE's NVMe Direct FIO bundle. SR100i NVMe RAID covers 2 U.3 NVMe SSDs and does not support U.2 drives.

How many drives does the DL365 Gen10 Plus hold?

Up to 10 SFF drives: 8 in the front and 2 in the media bay, by HPE's count. HPE offers no rear drive cages and no LFF model for it.

Can I run SATA drives without a RAID controller?

Yes. The 8SFF SAS/SATA drive cage can be direct attached with HPE's 8SFF SATA Direct Attach Cable Kit (P44886-B21). The embedded SR100i software RAID covers up to 8 SFF SATA drives; it runs in UEFI mode only and supports Microsoft Windows Server only, and the embedded controller works in AHCI mode by default.

What boot and optical options does the DL365 Gen10 Plus have?

HPE lists the NS204i-p NVMe OS boot device (P12965-B21) for slot 1 of the primary riser, and the NS204i-r M.2 riser (P26463-B21), which replaces the primary riser and takes HPE's NVMe M.2 SSDs. A 9.5mm SATA DVD-ROM or DVD-RW fits the media bay of the 8SFF CTO server, but not with a 2SFF drive cage or the M.2 kit (878783-B21).

Complete your DL365 Gen10 Plus

Drives HPE lists for the DL365 Gen10 Plus

From HPE QuickSpecs a50002558enw, Version 30 (July 28, 2025). A part not stocked today is priced on a quote request.

  • P12965-B21 HPE NS204i-p x2 Lanes NVMe PCIe3 x8 OS Boot Device
  • 701498-B21 HPE Mobile USB DVD-RW Optical Drive
  • 726536-B21 HPE 9.5mm SATA DVD-ROM Optical Drive
  • 726537-B21 HPE 9.5mm SATA DVD-RW Optical Drive
  • P40430-B21 HPE 300GB SAS 12G Mission Critical 10K SFF BC 3-year Warranty Multi Vendor HDD
  • P28586-B21 HPE 1.2TB SAS 12G Mission Critical 10K SFF BC 3-year Warranty Multi Vendor HDD
  • P28352-B21 HPE 2.4TB SAS 12G Mission Critical 10K SFF BC 3-year Warranty 512e Multi Vendor HDD
  • P53561-B21 HPE 600GB SAS 12G Mission Critical 10K SFF BC 3-year Warranty Multi Vendor HDD
  • P53562-B21 HPE 1.8TB SAS 12G Mission Critical 10K SFF BC 3-year Warranty 512e Multi Vendor HDD
  • P28618-B21 HPE 2.4TB SAS 12G Mission Critical 10K SFF BC 3yr Wty 512e FIPS 140-2 TAA-compliant HDD
  • P28622-B21 HPE 1.2TB SAS 12G Mission Critical 10K SFF BC 3yr Wty FIPS 140-2 TAA-compliant HDD
  • P40506-B21 HPE 960GB SAS 12G Read Intensive SFF BC Value SAS Multi Vendor SSD
  • P49029-B21 HPE 960GB SAS 24G Read Intensive SFF BC Multi Vendor SSD
  • P40507-B21 HPE 1.92TB SAS 12G Read Intensive SFF BC Value SAS Multi Vendor SSD
  • P49031-B21 HPE 1.92TB SAS 24G Read Intensive SFF BC Multi Vendor SSD
  • P40508-B21 HPE 3.84TB SAS 12G Read Intensive SFF BC Value SAS Multi Vendor SSD
  • P49035-B21 HPE 3.84TB SAS 24G Read Intensive SFF BC Multi Vendor SSD
  • P40509-B21 HPE 7.68TB SAS 12G Read Intensive SFF BC Value SAS Multi Vendor SSD
  • P49041-B21 HPE 7.68TB SAS 24G Read Intensive SFF BC Multi Vendor SSD
  • P49045-B21 HPE 15.36TB SAS 24G Read Intensive SFF BC Multi Vendor SSD
  • P49047-B21 HPE 800GB SAS 24G Mixed Use SFF BC Multi Vendor SSD
  • P40510-B21 HPE 960GB SAS 12G Mixed Use SFF BC Value SAS Multi Vendor SSD
  • P49049-B21 HPE 1.6TB SAS 24G Mixed Use SFF BC Multi Vendor SSD
  • P40511-B21 HPE 1.92TB SAS 12G Mixed Use SFF BC Value SAS Multi Vendor SSD
  • P49053-B21 HPE 3.2TB SAS 24G Mixed Use SFF BC Multi Vendor SSD
  • P40512-B21 HPE 3.84TB SAS 12G Mixed Use SFF BC Value SAS Multi Vendor SSD
  • P49057-B21 HPE 6.4TB SAS 24G Mixed Use SFF BC Multi Vendor SSD
  • P40502-B21 HPE 480GB SATA 6G Mixed Use SFF BC Multi Vendor SSD
  • P40503-B21 HPE 960GB SATA 6G Mixed Use SFF BC Multi Vendor SSD
  • P40504-B21 HPE 1.92TB SATA 6G Mixed Use SFF BC Multi Vendor SSD
  • P40505-B21 HPE 3.84TB SATA 6G Mixed Use SFF BC Multi Vendor SSD
  • P40496-B21 HPE 240GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
  • P40497-B21 HPE 480GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
  • P47818-B21 HPE 480GB SATA 6G Read Intensive M.2 Multi Vendor SSD
  • P40498-B21 HPE 960GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
  • P40499-B21 HPE 1.92TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
  • P40500-B21 HPE 3.84TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
  • P40501-B21 HPE 7.68TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
  • P64999-B21 HPE 800GB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
  • P65007-B21 HPE 1.6TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
  • P65015-B21 HPE 3.2TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
  • P65023-B21 HPE 6.4TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
  • P51459-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.2 P5620 SSD
  • P63845-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
  • P50227-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PM1735a SSD
  • P51461-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.2 P5620 SSD
  • P63849-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
  • P50230-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PM1735a SSD
  • P70426-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PS1030 SSD
  • P63853-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
  • P50233-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PM1735a SSD
  • P70428-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PS1030 SSD
  • P64842-B21 HPE 960GB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
  • P64844-B21 HPE 1.92TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
  • P64846-B21 HPE 3.84TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
  • P64848-B21 HPE 7.68TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
  • P69255-B21 HPE 15.36TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static SPDM Multi Vendor SSD
  • P63829-B21 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
  • P50216-B21 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PM1733a SSD
  • P51455-B21 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.2 P5520 SSD
  • P63833-B21 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
  • P50219-B21 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PM1733a SSD
  • P63837-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
  • P50222-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PM1733a SSD
  • P70434-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PS1010 SSD
  • P63841-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
  • P70436-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PS1010 SSD
  • P50224-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PM1733a SSD
  • P40513-B21 HPE 480GB NVMe Gen3 Mainstream Performance Read Intensive M.2 Multi Vendor SSD
  • P69543-B21 HPE 480GB NVMe Gen4 Mainstream Performance Read Intensive M.2 PM9A3 SSD
  • P58236-B21 HPE 480GB SATA 6G Read Intensive SFF BC Self-encrypting 5400P SSD
  • P58244-B21 HPE 960GB SATA 6G Mixed Use SFF BC Self-encrypting 5400M SSD
  • 666987-B21 HPE Small Form Factor Hard Drive Blank Kit
Ships same dayMost orders ship the same business day
1 to 5 year warrantyTested or factory sealed

All HPE ProLiant DL365 Gen10 Plus Drives

Part number Capacity Interface Class Price Quantity and add
P58244-B21 HPE 960GB SATA 6G Mixed Use SFF BC Self‑encrypting 5400M SSD - Refurbished
Price on requestOut of stock
P63829-B21 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
Price on requestOut of stock
P63833-B21 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
MXN$77,623.21In stock
P63837-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
Price on requestOut of stock
P63841-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
Price on requestOut of stock
P63845-B21 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
MXN$47,324.39In stock
P63849-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
Price on requestOut of stock
P63853-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
MXN$73,908.20In stock
P64611-001 HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
Price on requestOut of stock
P64612-001 HPE 3.84TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
MXN$77,623.21In stock
P64613-001 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
Price on requestOut of stock
P64614-001 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 CM7 SSD
Price on requestOut of stock
P64615-001 HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
MXN$47,324.39In stock
P64616-001 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 CM7 SSD
Price on requestOut of stock
P64842-B21 HPE 960GB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
MXN$33,528.45In stock
P64844-B21 HPE 1.92TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
MXN$41,406.51In stock
P64846-B21 HPE 3.84TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
Price on requestOut of stock
P64848-B21 HPE 7.68TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
MXN$82,420.99In stock
P64999-B21 HPE 800GB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
MXN$26,117.09In stock
P65007-B21 HPE 1.6TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
MXN$41,406.51In stock
P65015-B21 HPE 3.2TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
MXN$55,967.86In stock
P65023-B21 HPE 6.4TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
MXN$119,253.74In stock
P65191-001 HPE 960GB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
MXN$33,528.45In stock
P65193-001 HPE 1.92TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
MXN$41,406.51In stock
P65195-001 HPE 3.84TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static V2 Multi Vendor SSD
Price on requestOut of stock
P65201-001 HPE 800GB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
MXN$26,117.09In stock
P65203-001 HPE 1.6TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
MXN$41,406.51In stock
P65205-001 HPE 3.2TB NVMe Gen4 Mainstream Performance Mixed Use SFF BC U.3 Static V2 Multi Vendor SSD
MXN$55,967.86In stock
P69255-B21 HPE 15.36TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static SPDM Multi Vendor SSD
Price on requestOut of stock
P69507-001 HPE 15.36TB NVMe Gen4 Mainstream Performance Read Intensive SFF BC U.3 Static SPDM Multi Vendor SSD
Price on requestOut of stock
P69543-B21 HPE 480GB NVMe Gen4 Mainstream Performance Read Intensive M.2 PM9A3 SSD - Refurbished
MXN$27,218.53In stock
P70426-B21 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PS1030 SSD
Price on requestOut of stock
P70428-B21 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PS1030 SSD
Price on requestOut of stock
P70434-B21 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PS1010 SSD
Price on requestOut of stock
P70436-B21 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PS1010 SSD
Price on requestOut of stock
P70497-001 HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PS1030 SSD
Price on requestOut of stock
P70498-001 HPE 6.4TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PS1030 SSD
Price on requestOut of stock
P70501-001 HPE 7.68TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PS1010 SSD
Price on requestOut of stock
P70502-001 HPE 15.36TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PS1010 SSD
Price on requestOut of stock

Prices are today's store prices.

Ships same dayMost orders ship the same business day
1 to 5 year warrantyReplacement coverage on every part
5,000+ five-star reviewsShopper Approved, BBB A+ rating
Ships to 120+ countriesBy UPS; duties are collected by the carrier

Filling several servers, or a different model?

Send the drives you want for each server and we reply to every quote request within 24 hours. Live chat is the fastest way to reach us.