HPE ProLiant DL345 Gen11 Memory
Upgrade your HPE ProLiant DL345 Gen11 with genuine HPE DDR5 Smart Memory, in stock new and refurbished and tested before shipping. This single-socket platform runs 12 DIMM slots on 12 channels at 1 DIMM per channel, and the installed EPYC generation sets the speed grade.
DL345 Gen11 Memory Specifications
- Memory type: HPE DDR5 Smart Memory, EC8 Registered (RDIMM) — LRDIMM and Persistent Memory are not supported
- Slots: 12 DIMM slots, 12 channels per processor, 1 DIMM per channel
- Speed grades: DDR5-4800 kits apply to the 4th Generation AMD EPYC processors; DDR5-6400 kits apply to the 5th Generation
- Capacities: 16GB, 32GB, 64GB, 96GB, and 128GB kits in both speed grades, plus a 256GB Quad Rank x4 3DS kit listed under DDR5-6400
- Maximum capacity: 3.0TB — the QuickSpecs state 12 × 256GB RDIMM at 4800 MT/s at 1DPC for 4th Gen EPYC, and at 6400 MT/s at 1DPC for 5th Gen
- Population rules: quantity per socket must be 1, 2, 4, 6, 8, 10, or 12; mixing x4 with x8 is not supported, and mixing 3DS with non-3DS is not supported
Match the speed grade to your EPYC generation. The QuickSpecs list DDR5-4800 kits for 4th Generation AMD EPYC processors and DDR5-6400 kits for 5th Generation. Add one slower module and every DIMM runs at the slower speed, and the quantity per socket must be 1, 2, 4, 6, 8, 10, or 12.
How much memory can the DL345 Gen11 hold?
| Specification | 5th Gen AMD EPYC | 4th Gen AMD EPYC |
|---|---|---|
| Memory speed | 6400 MT/s | 4800 MT/s |
| Kit capacities listed | 16GB to 256GB 3DS | 16GB to 128GB |
| Module ranks listed | Single Rank x8 to Quad Rank x4 | Single Rank x8 to Dual Rank x4 |
| Maximum capacity | 3.0TB (12 × 256GB at 1DPC) | 3.0TB (12 × 256GB at 1DPC) |
The maximum speed of the memory system is governed by the processor together with every DIMM installed — add one slower module and every DIMM runs at the slower speed. Note that the QuickSpecs quote the same 3.0TB maximum for both generations while listing the 256GB 3DS kit only under DDR5-6400.
Choosing the Right DL345 Gen11 Memory
- Match the speed grade to your EPYC generation: DDR5-4800 for 4th Generation, DDR5-6400 for 5th Generation — both are EC8 RDIMMs that physically fit, so the wrong grade costs performance rather than failing.
- Install a legal quantity: 1, 2, 4, 6, 8, 10, or 12 DIMMs per socket — twelve identical modules is the only layout that fills every channel.
- Don't mix module types: x4 with x8 is not supported, and 3DS with non-3DS is not supported.
- 256GB DIMMs restrict the chassis: if 256GB memory is selected, the QuickSpecs state that the 4LFF Midtray, 8SFF x1 Midtray, and 8SFF x4 Midtray cannot be selected.
- Background reading: maximum memory configurations for Gen11 ProLiants, memory rank in HPE servers, and why memory speed matters.
Complete Your DL345 Gen11 Build
Pair memory with DL345 Gen11 processors, drives, storage controllers, networking adapters, and power supplies, or start from the full DL345 Gen11 parts page. Neighboring generation: DL345 Gen10 Plus memory. Sibling AMD Gen11 platforms: DL385 Gen11 memory and DL365 Gen11 memory. You can also browse all Gen11 server memory or parts by server model.
DL345 Gen11 Memory FAQ
How much RAM does the HPE ProLiant DL345 Gen11 support?
Up to 3.0TB. There are 12 DIMM slots on 12 channels at 1 DIMM per channel, and the QuickSpecs give the maximum as 12 x 256GB RDIMM.
What type of memory does the DL345 Gen11 use?
HPE DDR5 Smart Memory, EC8 Registered (RDIMM), in 16GB through 256GB kits. LRDIMM and Persistent Memory are not supported.
Should I buy DDR5-4800 or DDR5-6400 memory for the DL345 Gen11?
Match the speed grade to the processor generation. The QuickSpecs list the DDR5-4800 kits for 4th Generation AMD EPYC processors and the DDR5-6400 kits for 5th Generation. If faster DIMMs are mixed with slower DIMMs, all of them run at the slower speed.
How many DIMMs can I install in a DL345 Gen11?
The quantity per socket must be 1, 2, 4, 6, 8, 10, or 12. With 12 channels and one DIMM per channel, twelve identical modules fills every channel.
Can I mix x4 and x8 DDR5 modules in the DL345 Gen11?
No. Mixing x4 memory and x8 memory is not supported, and mixing 3DS memory with non-3DS memory is not supported.
What is the difference between -B21 and -F21 memory kits?
The -B21 SKUs are for ordering stand-alone memory, which is what a field upgrade needs. Each -B21 SKU has a corresponding -F21 SKU used only when configuring servers with factory-integrated memory DIMMs.
✅ Looking for a specific DL345 Gen11 memory module? Browse our full selection below.
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