HPE ProLiant ML350p Gen8 Processors
Genuine HPE processor option kits for the HPE ProLiant ML350p Gen8, new and refurbished. The server takes up to two Intel Xeon E5-2600 or E5-2600 v2 processors for 4 to 24 cores in total, and HPE does not support mixing different processor models — so a second CPU has to match the first exactly.
ML350p Gen8 Processor Specifications
- Sockets: two, on the Intel C600 chipset, for a total of 4, 8, 12, 16, 20 or 24 cores
- E5-2600 v2 kits stocked: the twelve-core E5-2697 v2 at 2.7GHz and 130W, the ten-core E5-2690 v2 and eight-core E5-2650 v2, down to the four-core E5-2603 v2 and 60W E5-2630L v2
- E5-2600 kits stocked: the eight-core E5-2690 at 2.9GHz and 135W through the E5-2670 and E5-2660, down to the dual-core E5-2637 and the 70W E5-2650L
- Cache: 30MB of level 3 cache on twelve-core parts, 25MB on ten-core, 20MB on eight-core, 15MB on six-core, 10MB on quad-core and 5MB on dual-core
- Features: Intel Hyper-Threading and Turbo Boost on the supporting models
- Upgrade path: moving from E5-2600 to E5-2600 v2 calls for the Processor Upgrade Lever Kit, part number 749245-B21
- Kit contents: every processor kit listed here is complete with heatsink and fan or fans
A second processor does far more than add cores. With one CPU installed, only 12 of the 24 DIMM slots are available and only expansion slots 1 to 4 work; the second opens the rest of both. It must be the same model as the first, and moving a server from E5-2600 to E5-2600 v2 also calls for the Processor Upgrade Lever Kit 749245-B21.
How Much Memory Speed Does Each Processor Allow?
| Class | Kits | Maximum memory speed |
|---|---|---|
| Performance, E5-2600 v2 | E5-2697 v2, E5-2690 v2, E5-2680 v2, E5-2670 v2, E5-2667 v2, E5-2650 v2, E5-2643 v2, E5-2637 v2 | 1866MHz |
| Base, E5-2600 v2 | E5-2640 v2, E5-2630 v2, E5-2620 v2, E5-2630L v2 | 1600MHz |
| Entry, E5-2600 v2 | E5-2609 v2, E5-2603 v2 | 1333MHz |
| Performance, E5-2600 | E5-2690 and E5-2680 through E5-2643 and E5-2637 | 1600MHz |
| Base and entry, E5-2600 | E5-2640, E5-2630, E5-2620, E5-2630L; E5-2609 and E5-2603 | 1333MHz and 1066MHz |
The processor, not the module, decides how fast memory runs here, and the gap is wide: an entry E5-2603 v2 holds DDR3 to 1333MHz whatever is in the slots, while an E5-2697 v2 allows 1866MHz. Wattage is the other axis a tower buyer feels — two 130W parts ask more of the fans and the supply than two 60W E5-2630L v2 kits, and in a floor-standing machine that is audible.
Choosing the Right ML350p Gen8 Processor
- Both sockets must carry the same model. Mixing processor models is not supported, so going to two CPUs means two identical kits unless the first is replaced as well.
- A second processor opens more than cores. It brings the other 12 DIMM slots into use and activates expansion slots 5 to 9, which is often the real reason to fit one.
- Going from E5-2600 to E5-2600 v2 needs the lever kit. HPE documents the Processor Upgrade Lever Kit 749245-B21 for that move, with a customer advisory setting out the limitations.
- Match the memory you already own. Dropping an entry v2 part into a server full of 1866MHz DIMMs throws away the speed you paid for.
- Check the power and cooling budget. Two 130W processors with three drive cages is a different proposition from two 60W parts, for the supply and the fans alike.
Complete Your ML350p Gen8 Build
Processor choice sets the memory clock and the power draw together — see ML350p Gen8 memory and power supplies alongside this page. Also available: drives, storage controllers and networking adapters, or the full ML350p Gen8 parts listing. Other models: HPE parts by server model.
ML350p Gen8 Processors FAQ
Which processors does the ML350p Gen8 support?
Intel Xeon E5-2600 and E5-2600 v2 series, up to two of them for 4 to 24 cores in total. The range runs from the twelve-core E5-2697 v2 down to the dual-core E5-2637.
Can I mix different processors in an ML350p Gen8?
No. HPE does not support mixing different processor models in the same server, so both sockets must carry the same part number.
Can I upgrade an ML350p Gen8 from E5-2600 to E5-2600 v2?
Yes, but not with the processor alone. HPE documents the ML350p Gen8 Processor Upgrade Lever Kit, part number 749245-B21, for servers moving from the original E5-2600 processors to the v2 series, plus a customer advisory covering the requirements.
Does adding a second processor do anything besides add cores?
Yes. With one processor installed only 12 of the 24 DIMM slots are available, and only expansion slots 1 to 4 work. The second CPU opens the rest of both.
Which processor gives the best memory speed?
A performance E5-2600 v2 part such as the E5-2697 v2 or E5-2690 v2, which support DDR3 at 1866MHz. Base v2 parts cap at 1600MHz, entry v2 parts at 1333MHz, and the original E5-2600 series at 1600MHz or lower.
Do ML350p Gen8 processor kits include a heatsink?
Yes. Every processor option kit listed for this server comes complete with heatsink and fan or fans.
✅ Looking for a specific ML350p Gen8 processor? Browse our full selection below.


