HPE ProLiant ML350 Gen10 Memory
Genuine HPE DDR4 Smart Memory for the HPE ProLiant ML350 Gen10, new and refurbished. The tower carries 24 DIMM slots, six channels per processor and two DIMMs per channel, and two rules decide every order: Registered and Load Reduced cannot be mixed, and DDR4-2933 kits belong to Second Generation Xeon Scalable processors while DDR4-2666 kits belong to the first.
ML350 Gen10 Memory Specifications
- Type: HPE DDR4 Smart Memory as Registered (RDIMM) or Load Reduced (LRDIMM), in DDR4-2933 CAS-21 and DDR4-2666 CAS-19 grades
- Slots: 24 in total, twelve per processor across six channels at two DIMMs per channel; with one processor installed only 12 are available
- Maximum registered: 1.5TB, using twenty-four 64GB dual-rank RDIMMs at 2933 MT/s
- Maximum load reduced: 3TB, using twenty-four 128GB LRDIMMs at 2933 MT/s, which is the documented ceiling for DDR4 on this platform
- Processor cap: the ceiling per socket is set by the CPU, not the slots — an unsuffixed Xeon Scalable part addresses 1TB per socket, an M part 2TB and an L part 4.5TB
- Mixing: RDIMM and LRDIMM cannot run together, and HPE ties each DDR4 grade to its own processor generation
Two mixing rules, and the second one catches people who got the first one right. Registered and Load Reduced DIMMs cannot run together — and DDR4-2933 kits are supported only with Second Generation Intel Xeon Scalable processors, where DDR4-2666 kits belong to the first generation. Check which processor is fitted before ordering, because the CPU also caps the memory per socket at 1TB, 2TB or 4.5TB by suffix.
How Fast Will Your DIMMs Actually Run?
| Processor series | One DIMM per channel | Two DIMMs per channel |
|---|---|---|
| Platinum 8200 and Gold 6200 | 2933 MT/s | 2666 MT/s |
| Gold 5200 | 2666 MT/s, or 2933 MT/s on the 5222 | 2666 MT/s |
| Silver 4200 | 2400 MT/s | 2400 MT/s |
| Bronze 3200 | 2133 MT/s | 2133 MT/s |
The module is rarely what sets the speed here. A Silver 4210R holds DDR4 to 2400 MT/s and a Bronze 3204 to 2133 MT/s whatever is fitted, so a DDR4-2933 kit bought for a Silver or Bronze machine is paying for headroom the processor will not use. On Platinum and Gold 6200 parts the second DIMM in a channel is what costs the clock, which is why filling 24 slots with smaller modules runs slower than reaching the same capacity with twelve larger ones.
Choosing the Right ML350 Gen10 Memory
- Match the DDR4 grade to the processor generation. HPE states that DDR4-2933 kits are supported only with Second Generation Intel Xeon Scalable processors and DDR4-2666 kits only with the first generation.
- Never mix Registered and Load Reduced. The two are not supported together, so converting a machine from one to the other means replacing every module in it.
- Count processors before counting slots. One processor exposes 12 slots; the other 12 arrive only with the second CPU, whatever memory you buy.
- Check the suffix if you are chasing capacity. Reaching 3TB needs processors rated above the 1TB-per-socket baseline, because the CPU caps the socket before the DIMM count does.
- Every HPE DDR4 option kit here is a single DIMM. Filling all 24 slots means 24 kits, not one boxed set.
Complete Your ML350 Gen10 Build
The processor sets the memory clock and the per-socket ceiling as firmly as the module does — check the ML350 Gen10 processors before paying for 2933 MT/s kits. Also available: ML350 Gen10 drives, storage controllers, networking adapters and power supplies, or the full ML350 Gen10 parts listing. Background reading: understanding memory rank, what CAS latency means and the server memory upgrade checklist. Other models: HPE parts by server model.
ML350 Gen10 Memory FAQ
What is the maximum memory in an ML350 Gen10?
3TB with Load Reduced DIMMs, using twenty-four 128GB modules at 2933 MT/s, or 1.5TB with Registered DIMMs using twenty-four 64GB modules. A single-processor server reaches half of either figure, because only 12 of the 24 slots are available.
Can I mix RDIMM and LRDIMM in an ML350 Gen10?
No. HPE does not support mixing Registered and Load Reduced memory in this server. Whichever type is fitted today is what an upgrade must match, and converting means replacing every module.
Does an ML350 Gen10 take DDR4-2933 or DDR4-2666 memory?
It depends on the processor. HPE supports DDR4-2933 kits only with Second Generation Intel Xeon Scalable processors, and DDR4-2666 kits only with the first generation, so the CPU decides which grade the server will take.
How many memory slots does the ML350 Gen10 have?
Twenty-four, arranged as twelve per processor across six channels at two DIMMs per channel. With one processor installed, only twelve are usable.
Why does my ML350 Gen10 memory run below 2933 MT/s?
Either the processor or the population. Silver 4200 parts run the memory at 2400 MT/s and Bronze 3200 parts at 2133 MT/s regardless of the module, and on Platinum 8200 and Gold 6200 parts a second DIMM in each channel brings 2933 down to 2666.
Do HPE memory kits for this server contain more than one DIMM?
No. Every DDR4 option kit listed for this server is a single DIMM, so a 24-slot fill is 24 kits.
✅ Looking for a specific ML350 Gen10 memory module? Browse our full selection below.
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