This item, P51460-B21, is the HPE option part number for the product described as 3.2TB NVMe Gen4 High Performance Mixed Use SFF SCN U.2 P5620 SSD. Further details below.
The HPE 3.2TB NVMe Gen4 High Performance Mixed Use SFF SCN U.2 P5620 SSD (P51460-B21) is a genuine HPE 3.2TB solid state drive for mixed read and write workloads. It connects over PCIe Gen4 NVMe through a U.2 connector. It ships on an HPE Smart Carrier NVMe (SCN) for SFF (2.5-inch) bays, which HPE's carrier key decoder lists as a smart, hot-plug carrier.
HPE's server QuickSpecs list it for the three ProLiant models in the Compatible With section below, across Gen10 and Gen10 Plus. Every part ships tested or factory sealed and is backed by a 3-year replacement warranty.
HPE Option Part #: P51460-B21
HPE Spare Part #: P52330-001
PRODUCT SPECIFICATIONS FOR P51460-B21:
- Product Number: P51460-B21
- Capacity: 3.2TB
- Drive type: Solid state drive
- Interface: NVMe (PCIe Gen4)
- Connector: U.2
- Drive form factor: SFF (2.5-inch)
- Carrier type: Smart Carrier NVMe (SCN)
- Workload: Mixed Use
- Performance class: High Performance
- Drive model (in HPE's name): P5620
- Plug type: Hot pluggable
- Weight: 1.00 lb
- Warranty: 3 years
COMPATIBLE WITH:
PROLIANT DL SERIES
PROLIANT ML SERIES
** This list may not be complete. Check HPE's QuickSpecs for your server to verify compatibility.
FREQUENTLY ASKED QUESTIONS FOR P51460-B21:
- Which HPE ProLiant servers list P51460-B21?
HPE's server QuickSpecs list this drive for three ProLiant models, across Gen10 and Gen10 Plus: the DL325 Gen10 Plus, DL380 Gen10 and ML350 Gen10. The full list is in the Compatible With section of this page. - What carrier does P51460-B21 use and is it hot pluggable?
This drive ships on an HPE Smart Carrier NVMe (SCN) for SFF (2.5-inch) bays. HPE's carrier key decoder lists the SCN as a smart, hot-plug carrier (HPE Solid State Disk Drives QuickSpecs a00001288enw, version 77, page 88). - Does HPE publish performance figures for P51460-B21?
Not any more: HPE removed this drive from its Solid State Disk Drives QuickSpecs in version 67 (02-Jun-2025), so endurance and performance figures are not stated here. HPE's name classes it as High Performance and Mixed Use.
Last Updated: 2026-10-20
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- Form Factor/Carrier Type
- SFF / Smart Carrier (SC)
This product is warrantied against hardware failure for a period of 3 Years from the date of purchase. Before making a purchase, please take a moment to review our return policy below.
Returns
It is the customer's responsibility to verify compatibility with their machine(s) before placing an order. If an item is ordered by mistake, it can be returned for refund, minus a 25% restocking fee, within 5 business days of receipt. The cost of freight is not refundable.
Please be aware that factory-sealed equipment can only be returned if it remains unopened.
Defective Products
If you have received a defective part and your machine is still within the HPE warranty period, please initiate a warranty exchange by visiting the HPE Enterprise Support Center. Be sure to have the serial numbers of the defective drive and your server/storage array handy.
In case your hardware becomes defective during the Global One warranty period, but the HPE warranty has expired, you can return the product to us for a working replacement. You are responsible for the shipment of returned merchandise. However, we will cover the expense of Ground /Economy shipment for the replacement item(s).
Requesting an RMA
To initiate a return or warranty claim, please complete and submit the RMA Request Form.


