HPE ProLiant ML110 Gen10 Memory
Genuine HPE DDR4 Smart Memory for the HPE ProLiant ML110 Gen10, new and refurbished. This tower carries six DIMM slots, one on each channel of its single processor, and takes Registered DIMMs only — LRDIMMs are not qualified for this server, and HPE warns that mixing DIMM types can halt the machine during BIOS installation.
ML110 Gen10 Memory Specifications
- Type: HPE Smart Memory DDR4 Registered (RDIMM) only; LRDIMM is not qualified for this server, and all memory installed must be of the same type
- Slots: six, arranged as six channels with one DIMM per channel on the single processor
- Maximum capacity: 192GB, from six 32GB dual-rank RDIMMs at 2933 MT/s
- Generation rule: DDR4-2933 kits are supported only with second generation Intel Xeon Scalable processors, and DDR4-2666 kits only with first generation processors
- Kits stocked: 8GB single-rank x8, 16GB single-rank x4, 16GB dual-rank x8 and 32GB dual-rank x4 at DDR4-2933 CAS-21-21-21; 8GB single-rank x8, 16GB single-rank x4 and 32GB dual-rank x4 at DDR4-2666 CAS-19-19-19
- Kit contents: every HPE Smart Memory option kit listed for this server is a single DIMM
Registered only, and the kit generation follows the processor generation. LRDIMMs are not qualified for this server, and DDR4-2933 kits go with second generation Intel Xeon Scalable processors while DDR4-2666 kits go with first generation parts. Six slots, one per channel, a ceiling of 192GB on six 32GB modules — and every kit listed here is a single DIMM.
Which DDR4 Kit Matches Your Processor?
| Processor fitted | Registered kit to buy | Speed that processor rates |
|---|---|---|
| Second generation Gold 5222 | DDR4-2933 | 2933 MT/s |
| Second generation Gold 5215 or 5218N | DDR4-2933 | 2666 MT/s |
| Second generation Silver 4200 series | DDR4-2933 | 2400 MT/s |
| Second generation Bronze 3200 series | DDR4-2933 | 2133 MT/s |
| First generation Gold, Silver or Bronze | DDR4-2666 | 2133 to 2666 MT/s by model |
The kit generation follows the processor generation, and the clock follows the processor model — those are two separate things, and confusing them is what sends the wrong part back. A DDR4-2933 kit is the correct part number for a Silver 4210 machine and will still run at 2400 MT/s, because 2400 is what that processor rates. HPE puts it plainly: maximum memory speed is a function of the memory type, the memory configuration and the processor model.
Choosing the Right ML110 Gen10 Memory
- Identify the processor generation before the kit. DDR4-2933 kits pair with second generation x2xx parts and DDR4-2666 kits with first generation x1xx parts, and HPE does not support a field upgrade between the two — so the processor fitted decides the memory family for the life of the server.
- Fill all six channels where the budget allows. Six slots is one per channel, so six matched DIMMs is the only fully balanced configuration this platform has.
- 192GB means 32GB modules. Six 32GB dual-rank RDIMMs is the documented ceiling; nothing larger is qualified for this server.
- Every kit is one DIMM. A 96GB configuration is six 16GB kits, not a single boxed set.
- Do not mix DIMM types. HPE warns that mixing can cause the server to halt during BIOS installation, so a part-populated server dictates what the next module has to be.
Complete Your ML110 Gen10 Build
Memory speed is set by the processor as much as by the module, and the rest of the tower is here too: ML110 Gen10 drives, storage controllers, networking adapters, power supplies and rack options, or start from the full ML110 Gen10 parts listing. Background reading: understanding memory rank in HPE servers and the importance of memory speed.
ML110 Gen10 Memory FAQ
What is the maximum memory in an ML110 Gen10?
192GB, from six 32GB dual-rank DDR4 Registered DIMMs at 2933 MT/s. That is the ceiling for the platform, and HPE lists 192GB per socket against every documented processor for it.
How many memory slots does the ML110 Gen10 have?
Six, one on each of the single processor's six memory channels. There is no second bank to unlock, because there is no second socket.
Can I use LRDIMMs in an ML110 Gen10?
No. HPE has not qualified LRDIMMs for this server, and mixing LRDIMMs with RDIMMs can cause the server to halt during BIOS installation. All memory installed must be of the same type.
Do I need DDR4-2666 or DDR4-2933 kits?
It follows the processor generation. DDR4-2933 kits are supported with second generation Intel Xeon Scalable processors and DDR4-2666 kits with first generation parts.
Will a DDR4-2933 kit make the server run at 2933 MT/s?
Only if the processor rates that speed. Of the documented processors only the Gold 5222 runs memory at 2933 MT/s - Silver parts rate 2400 MT/s and Bronze parts 2133 MT/s.
Do HPE memory kits for this server contain more than one DIMM?
No. Every Smart Memory option kit listed for the ML110 Gen10 is a single DIMM, so filling all six slots takes six kits.
✅ Looking for a specific ML110 Gen10 memory module? Browse our full selection below.


