HPE ProLiant ML350 Gen9 Processors

Genuine HPE processor option kits for the HPE ProLiant ML350 Gen9, new and refurbished. The tower takes up to two Intel Xeon E5-2600 v3 or E5-2600 v4 processors on the Intel C610 chipset, and HPE does not support mixing different processor models — so a second CPU has to match the first exactly.

ML350 Gen9 Processor Specifications

• Sockets: two, taking four-core parts at one end and the 22-core E5-2699 v4 at 2.2GHz and 145W at the other
• E5-2600 v4 kits stocked: the E5-2699 v4 and 20-core E5-2698 v4, through the 18-core E5-2697 v4 and 16-core E5-2683 v4, down to the 3.5GHz four-core E5-2637 v4, plus the 55W E5-2630L v4 and 65W E5-2650L v4
• E5-2600 v3 kits stocked: the 18-core E5-2699 v3 and 14-core E5-2697 v3, through the 12-core E5-2690 v3 and 10-core E5-2650 v3, down to the 3.5GHz four-core E5-2637 v3, plus the 55W E5-2630L v3
• Cache: up to 55MB of level 3 cache on the E5-2699 v4, 45MB on 18-core parts and down to 10MB on quad-core
• Interconnect: 9.6GT/s QPI on performance parts, 8.0GT/s on mainstream parts and 6.4GT/s on the E5-2609 and E5-2603 entry parts
• Kit contents and SKU rule: every kit comes complete with heatsink and fans; HPE's own configuration rule is one -L21 kit for a single-processor server, and an -L21 plus a -B21 for two

A second processor does far more than add cores. With one CPU installed, only 12 of the 24 DIMM slots are available and only four of the nine expansion slots work — slots 5 to 9 belong to the second processor. It must be the same model as the first, because HPE does not support mixing processor models in one server.

How Much Memory Speed Does Each Processor Allow?

The processor, not the module, sets the memory clock here, and the spread is wide: an E5-2609 v3 holds DDR4 to 1600MT/s whatever is in the slots, while an E5-2699 v4 allows 2400MT/s. Wattage is the other axis a tower buyer feels — two 145W parts ask more of the fans and the supply than two 55W E5-2630L kits, and in a floor-standing machine that difference is audible.

Choosing the Right ML350 Gen9 Processor

• Both sockets must carry the same model. Mixing processor models is not supported, so moving to two CPUs means two identical kits unless the first is being replaced as well.
• A second processor opens more than cores. It brings the other 12 DIMM slots into use and activates expansion slots 5 to 9, which is often the real reason to fit one.
• Match the memory you already own. Dropping an entry part into a server full of DDR4-2400 kits throws away the speed those modules were bought for.
• Swapping v3 for v4 does not unlock everything v4 offers. HPE supports NVDIMMs only on servers factory-configured with E5-2600 v4 processors, not on machines upgraded from v3.
• Check the power and cooling budget. Two 145W processors with several drive cages is a different proposition from two 55W parts, for the supply and the fans alike.

Complete Your ML350 Gen9 Build

Processor choice sets the memory clock and the power draw together — see ML350 Gen9 memory and power supplies alongside this page. Also available: ML350 Gen9 drives, storage controllers and networking adapters, or the full ML350 Gen9 parts listing. Other models: HPE parts by server model.

ML350 Gen9 Processors FAQ

Which processors does the ML350 Gen9 support?
Intel Xeon E5-2600 v3 and E5-2600 v4 series, up to two of them. Core counts run from four per processor to the 22-core E5-2699 v4, with wattages from 55W on the E5-2630L parts to 145W at the top of each generation.

Can I mix different processors in an ML350 Gen9?
No. HPE does not support mixing different processor models in the same server, so both sockets must carry the same part.

Does adding a second processor do anything besides add cores?
Yes. It makes the other 12 DIMM slots usable and brings expansion slots 5 to 9 online. With one processor installed, half the memory capacity and five of the nine slots are unavailable.

What is the difference between a -B21 and an -L21 processor kit?
They are the same processor in different configuration roles. HPE's rule is one -L21 kit for a single-processor server, and one -L21 plus one -B21 when two processors are wanted.

Do ML350 Gen9 processor kits include a heatsink?
Yes. Every processor kit listed for this server comes complete with heatsink and fans.

Which processor gives the fastest memory?
A performance E5-2600 v4 part such as the E5-2690 v4 or E5-2699 v4, which allow DDR4 at 2400MT/s. Entry parts are capped much lower - the E5-2609 v3 and E5-2603 v3 hold memory at 1600MT/s.

✅ Looking for a specific ML350 Gen9 processor? Browse our full selection below.

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