HPE ProLiant ML110 Gen10 Parts
The HPE ProLiant ML110 Gen10 is the single-socket 4.5U tower built on the Intel C621 chipset, taking one Intel Xeon Scalable processor across six DDR4 Registered DIMM slots, with a front end fixed by the drive cage it was built with. Every part below is genuine HPE, available new and refurbished, and tested for compatibility before it ships. Live pricing for each part number appears in the tables further down this page.
ML110 Gen10 Platform at a Glance
- Form factor: a 4.5U tower, 17.32in (H) × 7.68in (W) × 18.92in (D), 29.82 lb to 55.0 lb by configuration
- Processor: one Intel Xeon Scalable processor, first or second generation, in Bronze, Silver and Gold classes from six to sixteen cores and up to 110W; HPE does not support a field upgrade between the two generations
- Memory: six DDR4 Registered DIMM slots, one per channel, to a maximum of 192GB on six 32GB RDIMMs at 2933 MT/s; LRDIMMs are not qualified for this server
- Drive bays: eight non-hot-plug 3.5-inch SATA, four hot-plug LFF upgradable to eight, or eight hot-plug SFF upgradable to sixteen — cage types cannot be mixed
- Maximum internal storage: 160TB on eight 20TB LFF drives, 38.4TB on sixteen 2.4TB SFF SAS, and 245.76TB on sixteen 15.36TB SFF SAS SSDs
- Storage controller: embedded HPE Smart Array S100i SR Gen10 software RAID over ten SATA ports, or a plug-in Smart Array E208 or P408 SR Gen10 card
- Networking: two embedded Gigabit ports from an HPE Ethernet 1Gb 2-port 332i Adapter, with a separate iLO management port at the rear
- Expansion: five PCIe 3.0 slots, all full-height — slots 1 and 4 at x16, slot 3 at x8, slots 2 and 5 at x4 in x8 connectors
- Power and cooling: a fixed 550W ATX supply as standard, or hot-plug 800W Flex Slot Platinum supplies on the enablement kit; one system fan and one PCIe fan as standard, redundant fan kit optional
- Management: embedded HPE iLO 5 with an iLO Service Port on the front panel, an internal microSD slot, and UEFI by default
Two things decide most ML110 Gen10 orders: the drive cage and the processor generation. Three front ends exist — non-hot-plug LFF, hot-plug LFF and hot-plug SFF — and mixing cage types is not allowed, so a second cage has to match the first. HPE also does not support a field upgrade from a first generation x1xx processor to a second generation x2xx part, and that same split decides whether the server takes DDR4-2666 or DDR4-2933 memory.
Specifications on this page are taken from the HPE QuickSpecs for this server, HPE ProLiant ML110 Gen10 Server QuickSpecs, Version 36.
Shop ML110 Gen10 Parts by Category
- ML110 Gen10 memory — 8GB, 16GB and 32GB DDR4-2666 and DDR4-2933 Registered Smart Memory kits
- ML110 Gen10 drives — SAS and SATA drives in 2.5-inch SFF and 3.5-inch LFF, 12G SAS and 6G SATA SSDs, and SATA M.2
- ML110 Gen10 storage controllers — Smart Array E208i-p, E208e-p, P408i-p and P408e-p SR Gen10 cards, plus the Smart Storage Battery
- ML110 Gen10 networking adapters — Gigabit and 10 Gigabit Ethernet cards in BASE-T and SFP+
- ML110 Gen10 power supplies — 550W ATX, 800W Flex Slot Platinum hot-plug and the redundant power supply enablement kit
- ML110 Gen10 rack options — the ML Gen10 tower to rack conversion kit, shelf and cable management arm
Working on a different ML110? We also stock parts for the HPE ProLiant ML110 G6 and HPE ProLiant ML110 G7. Elsewhere in the Gen10 tower line: the smaller HPE ProLiant ML30 Gen10 and the two-socket HPE ProLiant ML350 Gen10.
ML110 Gen10 Parts FAQ
What processor does the ML110 Gen10 take?
One Intel Xeon Scalable processor, first or second generation, in Bronze, Silver and Gold classes from six to sixteen cores and up to 110W. A field upgrade from an x1xx part to an x2xx part is not supported.
How much memory can an ML110 Gen10 take?
192GB, from six 32GB DDR4 Registered DIMMs at 2933 MT/s. The server has six DIMM slots, one on each memory channel, and LRDIMMs are not qualified for it.
How many drives fit in an ML110 Gen10?
It depends on the cage: up to eight non-hot-plug 3.5-inch SATA drives, four hot-plug LFF bays upgradable to eight, or eight hot-plug SFF bays upgradable to sixteen. Mixing cage types is not allowed.
Does the ML110 Gen10 have a RAID controller built in?
Yes, the Smart Array S100i SR Gen10 software RAID. It supports RAID 0, 1, 5 and 10 on SATA drives on the embedded ports, runs in UEFI mode only, and is off by default.
Can an ML110 Gen10 be mounted in a rack?
Yes, using the HPE ML Gen10 Tower to Rack Conversion Kit - a sliding rail rack shelf with a cable management arm. HPE describes the rail tray as taking 1U of height in a standard rack.
Is the ML110 Gen10 a redundant server?
Only where it was built that way. One system fan and one PCIe fan ship as standard, and the 550W ATX supply is a single fixed unit. Redundancy means the enablement kit, two matching Flex Slot supplies and the redundant fan kit.
✅ Looking for a specific ML110 Gen10 part? Browse our full selection below.


