HPE ProLiant ML350 Gen11 Memory
Genuine HPE DDR5 Smart Memory for the HPE ProLiant ML350 Gen11, new and refurbished. The server carries 32 Registered DIMM slots — sixteen per processor, eight channels each, two DIMMs per channel — and the processor generation picks the module: DDR5-4800 kits go with 4th Generation Intel Xeon Scalable processors, DDR5-5600 kits with 5th Generation.
ML350 Gen11 Memory Specifications
- Type: HPE DDR5 Smart Memory, Registered (RDIMM) only — no unbuffered or load-reduced option
- Slots: 32, sixteen per processor across eight channels at two DIMMs per channel; all 32 require two processors
- Maximum capacity: 8.0TB from thirty-two 256GB RDIMMs at 4400 MT/s, on 4th and 5th Generation processors alike
- Speed grades: DDR5-4800 with 4th Generation processors, DDR5-5600 with 5th; actual speed depends on module, population and processor
- Supported populations: the DIMM count per socket must be 1, 2, 4, 6, 8, 12 or 16 — other counts are not documented arrangements
- Protection: Advanced ECC with single device data correction, covering errors within one DRAM chip
The processor generation picks the module, and the choice is permanent. DDR5-4800 kits go with 4th Generation Intel Xeon Scalable processors and DDR5-5600 kits with 5th Generation, and both families top out at the same 8.0TB. Because HPE does not support a field upgrade from a 4th Generation part to a 5th Generation one, the speed grade fitted today is the one the server keeps.
Which DDR5 Kit Matches Your Processors?
| 4th Gen Xeon Scalable | 5th Gen Xeon Scalable | |
|---|---|---|
| DIMM speed grade | DDR5-4800 | DDR5-5600 |
| Kit sizes listed | 16GB, 32GB, 64GB, 96GB, 128GB, 256GB | 16GB, 32GB, 64GB, 96GB, 128GB |
| Maximum capacity | 8.0TB, 32 × 256GB at 4400 MT/s | 8.0TB, 32 × 256GB at 4400 MT/s |
| Mixing x4 and x8 modules | Not allowed | Not allowed |
Both families reach the same 8.0TB ceiling, so this is a compatibility question rather than a capacity one — and it is settled once. HPE does not support a field upgrade from a 4th Generation processor to a 5th, so the speed grade fitted today is the one the server keeps.
Choosing the Right ML350 Gen11 Memory
- Populate in supported quantities. Per socket the count must be 1, 2, 4, 6, 8, 12 or 16 — a bank of ten is not an arrangement HPE documents.
- Never mix x4 and x8 modules. The rule appears on both speed grades, and breaking it turns a sound-looking upgrade into a server that will not train its memory.
- 96GB modules carry extra rules. Supported only at 8 or 16 DIMMs per processor, for totals of 8, 16 or 32, and never mixed with other capacities.
- 256GB modules need cooling headroom. HPE limits them to a 25°C maximum inlet temperature without the Redundant Fan Kit, and 30°C with it.
- Order the -B21 kit, not the -F21. The -B21 SKUs are stand-alone memory; -F21 exists only for DIMMs integrated at the factory.
Complete Your ML350 Gen11 Build
Memory speed is set by the processor as much as by the module — see the ML350 Gen11 processors first. For the rest of the server, browse ML350 Gen11 drives, storage controllers, networking adapters and power supplies, or the full ML350 Gen11 parts listing. Background reading: maximum memory configurations for Gen11 servers and understanding memory rank, or browse HPE parts by server model.
ML350 Gen11 Memory FAQ
What is the maximum memory in an ML350 Gen11?
8.0TB, reached with thirty-two 256GB Registered DDR5 modules at 4400 MT/s and two DIMMs per channel. That figure holds on both 4th and 5th Generation processors.
How many memory slots does the ML350 Gen11 have?
Thirty-two, arranged sixteen per processor across eight channels at two DIMMs per channel. With one processor installed, sixteen are usable.
Can I use DDR5-5600 memory in an ML350 Gen11?
The DDR5-5600 modules are the ones HPE lists for 5th Generation processors, and DDR5-4800 for 4th Generation. Match the speed grade to the processor generation already in the server.
How many DIMMs can I install per processor?
The quantity per socket must be 1, 2, 4, 6, 8, 12 or 16. Counts outside that list are not documented populations, whatever capacity the modules are.
Can I mix x4 and x8 DDR5 modules?
No. Mixing x4 and x8 memory is not allowed on either speed grade, and the 96GB modules cannot be mixed with any other capacity at all.
Why does my ML350 Gen11 memory run at 4400 MT/s?
Two reasons are common. A server filled to two DIMMs per channel with 256GB modules is rated at 4400 MT/s, and several processors - among them the Gold 6430, 5420+, 5418Y and 5416S - cap memory at 4400 MT/s however the slots are filled.
✅ Looking for a specific ML350 Gen11 memory module? Browse our full selection below.
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