HPE ProLiant DL580 Gen12 Parts
The HPE ProLiant DL580 Gen12 is HPE's mission-critical 4U platform, built around up to four Intel Xeon 6 processors, 64 DDR5 DIMM slots, and PCIe Gen5 I/O for databases, virtualization, and in-memory workloads such as SAP HANA. Every part below is genuine HPE, available new and refurbished, and tested for compatibility with the DL580 Gen12 before it ships. Live pricing for each part number appears in the tables further down this page.
DL580 Gen12 Platform at a Glance
- Processors: up to four Intel Xeon 6 P-core CPUs, 8 to 86 cores each (up to 344 cores per server)
- Memory: 64 DIMM slots (16 per processor), DDR5-6400 ECC RDIMM, up to 16TB
- Storage: hot-plug 2.5-inch SFF (U.3) and EDSFF E3.S bays — up to 32 drives, plus a front 2SFF option via the Universal Media Bay; no LFF bays on this model
- Expansion: up to 12 full-height PCIe 5.0 slots plus OCP 3.0 slots A and B
- Power: M-CRPS Titanium hot-plug power supplies, 1500W–3200W (plus a –48VDC option)
- Management: HPE iLO 7 with Intelligent Provisioning
Know what carries over before you order. The DL580 Gen12 shares memory, drives, controllers, and adapters with other Gen12 ProLiants, but chassis-specific parts — drive cages, risers, heat sinks, and its M-CRPS power supplies — are DL580-specific. When in doubt, match the part listings on each page below.
Full platform detail is in the official HPE DL580 Gen12 QuickSpecs.
Shop DL580 Gen12 Parts by Category
- DL580 Gen12 Memory — DDR5-6400 RDIMMs from 64GB to 256GB
- DL580 Gen12 Drives — NVMe, SAS, and SATA SSDs plus 10K SAS HDDs in SFF and EDSFF
- DL580 Gen12 Storage Controllers — MR-series RAID controllers, HBAs, and cache batteries
- DL580 Gen12 Networking Adapters — 1GbE to 100GbE in PCIe and OCP 3.0
- DL580 Gen12 Power Supplies — M-CRPS Titanium hot-plug PSUs
- DL580 Gen12 Processors — Intel Xeon 6 CPUs and heat sinks
Moving between generations or models? See DL580 Gen10 parts, the 2U DL380 Gen12 parts page, or browse all HPE parts by server model.
DL580 Gen12 Parts FAQ
Is the HPE ProLiant DL580 Gen12 a 2-processor or 4-processor server?
Both. The DL580 Gen12 runs with two or four Intel Xeon 6 processors. Memory slots and PCIe connectivity scale with the installed CPUs, and power supply rules differ: 2-processor systems use one or two PSUs, while 4-processor systems require two or four.
How much memory does the DL580 Gen12 support?
Up to 16TB of DDR5, using 256GB 3DS RDIMMs in all 64 slots with four processors installed. Modules run at up to 6400 MT/s, and supported capacities are 64GB, 96GB, 128GB, and 256GB.
What drives does the DL580 Gen12 accept?
Hot-plug 2.5-inch SFF drives on U.3 Basic Carriers and EDSFF E3.S NVMe drives, in configurations up to 32 bays (including mixed 16 SFF + 16 EDSFF). NVMe, SAS, and SATA interfaces are all supported; there are no 3.5-inch LFF bays on this model.
Does the DL580 Gen12 use the same parts as the DL380 Gen12?
Many options are shared, including DDR5 memory kits, most drives, MR-series storage controllers, and network adapters, but chassis-specific parts such as drive cages, risers, heat sinks, and M-CRPS power supplies are DL580-specific. Check the part listings on each page, or contact us to confirm.
Can I mix new and refurbished parts in the DL580 Gen12?
Yes. Genuine HPE parts perform identically whether new or refurbished, and our refurbished stock is tested before shipping. Many customers pair new drives with refurbished memory or controllers to balance budget and lead time.
✅ Looking for a specific DL580 Gen12 part? Browse our full selection above, or contact our HPE specialists for a guaranteed-compatible recommendation.


