HPE ProLiant DL385 Gen10 Power Supplies
Genuine HPE Flex Slot power supplies for the HPE ProLiant DL385 Gen10, new and refurbished. The platform takes one or two hot-plug PSUs in its two Flex Slot bays — two matching supplies give full 1+1 redundancy with tool-less replacement.
DL385 Gen10 Power Supply Specifications
- Family: HPE Flex Slot hot-plug, tool-less modules shared across the ProLiant Gen10 performance line
- AC options: 500W Platinum, 800W Platinum, 800W Titanium, and 1600W Platinum, all Low Halogen
- DC and universal options: an 800W -48VDC unit and an 800W Universal unit accepting 277VAC or 380VDC input
- Efficiency: the 500W and 1600W units are rated at 94%; the 800W is available in 94% and 96% versions
- Rules: both installed supplies must be the same model — HPE does not support mixing — and the 1600W unit accepts high-line 200–240VAC only
Both supplies must be the same model. HPE does not allow mixing two different power supplies in the DL385 Gen10, so when you add the second unit for 1+1 redundancy, order the exact part number already installed. The 1600W Flex Slot unit also needs high-line 200–240VAC and will not run on a low-line circuit.
How many power supplies does the DL385 Gen10 need?
| Configuration | PSUs | Typical choice |
|---|---|---|
| Light build: 1 CPU, few drives | 2 (1+1 redundant) | 500W Platinum |
| General-purpose 2P build | 2 (1+1 redundant) | 800W Platinum or Titanium |
| Loaded: 200W CPUs, 24 drives, GPU | 2 (1+1 redundant) | 1600W Platinum (high line) |
Production systems should run two supplies — hot-plug Flex Slot modules then let you replace a failed unit without downtime. Size the exact build with the HPE Power Advisor rather than guessing from CPU wattage alone.
Choosing the Right DL385 Gen10 Power Supply
- Never mix wattages or models — HPE states plainly that mixing two different power supplies is not allowed, so buy the exact part number already installed.
- Check your feed before ordering 1600W: that unit takes 200–240VAC only, so it is a non-starter on a low-line circuit.
- Titanium pays back on always-on systems: the 800W unit is offered in both 94% and 96% efficiency grades.
- Refurbished PSUs are a low-risk buy — sealed, tested modules, and the cheapest way to bring a single-supply server up to 1+1 redundancy.
Complete Your DL385 Gen10 Build
Pair redundant power with the rest of the platform: DL385 Gen10 memory, drives, storage controllers, networking adapters, processors, or the full DL385 Gen10 parts page. Related platforms: DL385 Gen10 Plus power supplies and the Intel-based DL380 Gen10 power supplies. Catalog-wide: HPE parts by server model.
DL385 Gen10 Power Supplies FAQ
What power supplies does the HPE ProLiant DL385 Gen10 use?
HPE Flex Slot hot-plug Low Halogen PSUs: 500W Platinum, 800W Platinum, 800W Titanium, and 1600W Platinum, plus an 800W -48VDC unit and an 800W Universal unit for 277VAC or 380VDC input.
Can I mix different power supplies in the DL385 Gen10?
No. HPE states that mixing two different power supplies is not allowed and that all power supplies in a server should match. When adding redundancy, order the exact part number already installed.
Does the 1600W power supply work on 110V power?
No. The 1600W Flex Slot unit supports high line voltage only, 200VAC to 240VAC. On a low-line circuit use the 500W or 800W options instead.
Can I hot-swap a failed DL385 Gen10 power supply?
Yes, provided two supplies are installed for 1+1 redundancy. Flex Slot modules are hot-plug and tool-less, so you pull the failed unit and slide in the replacement without shutting down.
How do I size a power supply for my DL385 Gen10?
Use the HPE Power Advisor. Processor wattage on this platform runs from 120W to 200W per socket, and drive count, GPUs, and the High Performance fan kit all add load, so a real configuration model beats a rule of thumb.
Are DL385 Gen10 and DL380 Gen10 power supplies interchangeable?
Both platforms use the HPE Flex Slot family with overlapping wattages, but always match the exact part number listed in your server's QuickSpecs, since the supported lineup differs between platforms.
✅ Looking for a specific DL385 Gen10 power supply? Browse our full selection below.


