HPE ProLiant DL384 Gen12 Drives

The HPE ProLiant DL384 Gen12 takes E3.S NVMe SSDs on the EC1 carrier in its front EDSFF bays, and up to two M.2 NVMe SSDs. The factory configuration sets how many E3.S drives it holds: 2 or 4 with one GH200 superchip, 4 or 8 with two. HPE states that the DL384 Gen12 supports neither hardware RAID controllers nor hot-pluggable drives, and recommends the M.2 drives, which run at PCIe Gen3, for boot.

  • Up to 8 E3.S NVMe Gen5 drives with two GH200 superchips
  • Up to 4 E3.S drives with one GH200 superchip
  • Up to two M.2 NVMe SSDs, recommended for boot
  • No hardware RAID controller, no hot-plug drives

Bays, carriers and counts on this page are from HPE's QuickSpecs for the DL384 Gen12, document a50009209enw, Version 16 (August 3, 2026).

Which drives fit the DL384 Gen12

The factory configuration sets how many E3.S bays the server has, and it cannot be upgraded in the field. HPE's counts:

BaysDrive carrierInterfacesMost drives
E3.SFront EDSFF bays, Gen5 x4 NVMeEC1NVMe: PCIe Gen5, and Gen4 Very Read OptimizedNo hardware RAID controller; drives are not hot-pluggable8 with two GH200 superchipsOne superchip: 2, or 4 in the 1 PCIe 4xEDSFF configuration
M.2M.2 2280NVMe Gen4 drives; the M.2 devices are PCIe Gen3Not in hardware RAID2

How many E3.S bays? How to tell

  1. Count the front E3.S bays. Two or four means one GH200 superchip; four or eight means two.
  2. Match the factory setting to the list: P72451-B21, P72454-B21 and P72457-B21 for one superchip (2, 2 and 4 drives); P72460-B21, P72463-B21 and P72466-B21 for two (4, 4 and 8 drives).
  3. Check the GH200 kit. P71406-B21 is the single-superchip kit (1P) and P71407-B21 the dual-superchip GH200 NVL2 kit (2P), both on server P71411-B21.
  • P71411-B21DL384 Gen12 server
  • P72451-B211P, 2 E3.S, 2 PCIe
  • P72454-B211P, 2 E3.S, 1 OCP
  • P72457-B211P, 4 E3.S
  • P72460-B212P, 4 E3.S, 4 PCIe
  • P72463-B212P, 4 E3.S, 2 OCP
  • P72466-B212P, 8 E3.S, 2 PCIe

Three rules before you order

NVMe only: E3.S EC1 and M.2

HPE lists E3.S EC1 NVMe SSDs for the front bays and M.2 2280 NVMe SSDs for the two M.2 positions. The M.2 devices run at PCIe Gen3, and HPE recommends them for boot drives, not for local cache.

No RAID controller, no hot plug

HPE states that this server supports neither hardware RAID controllers nor hot-pluggable drives. Boot options are set in HPE iLO: the M.2 NVMe drives, the E3.S NVMe drives, or PXE over the network.

The drive count is set at the factory

The maximum number of drives, PCIe and OCP is set at the factory and is not field upgradeable; the drives themselves may be upgraded. With two superchips, the unbalanced configuration (P72469-B21) fills the first GH200 first, and the balanced one (P72472-B21) places drives equally on both.

DL384 Gen12 drives FAQ

What drives fit the HPE ProLiant DL384 Gen12?

E3.S EC1 NVMe SSDs in the front EDSFF bays, and up to two M.2 2280 NVMe SSDs. HPE lists only NVMe drives for this server.

Can I hot-swap drives in the DL384 Gen12?

No. HPE states that in this NVIDIA Grace product generation neither hardware RAID controllers nor hot-pluggable drives are supported.

How many drives does the DL384 Gen12 hold?

Up to 8 E3.S drives with two GH200 superchips, plus up to two M.2 drives, by HPE's count. One superchip supports 2 E3.S drives, or 4 with one PCIe slot fewer.

Can I add more E3.S bays later?

No. The maximum number of drives, PCIe and OCP is set at the factory and is not field upgradeable. The drives themselves may be upgraded in the field.

What should the DL384 Gen12 boot from?

HPE recommends the M.2 drives for boot, not for local cache, because they are PCIe Gen3. Boot options are set in HPE iLO: the M.2 NVMe drives, the E3.S NVMe drives, or PXE over the network.

Complete your DL384 Gen12

Drives HPE lists for the DL384 Gen12

From HPE QuickSpecs a50009209enw, Version 16 (August 3, 2026). A part not stocked today is priced on a quote request.

  • P80327-B21 HPE 960GB NVMe Gen4 Mainstream Performance Read Intensive M.2 2280 Self-encrypting PE9010 SSD
  • P80318-B21 HPE 480GB NVMe Gen4 Mainstream Performance Read Intensive M.2 2280 PE9010 SSD
  • P80321-B21 HPE 960GB NVMe Gen4 Mainstream Performance Read Intensive M.2 2280 PE9010 SSD
  • P80324-B21 HPE 1.92TB NVMe Gen4 Mainstream Performance Read Intensive M.2 2280 PE9010 SSD
  • P57799-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM PM1743 SSD
  • P57807-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM PM1743 SSD
  • P61179-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM CM7 SSD
  • P61183-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM CM7 SSD
  • P61187-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM CM7 SSD
  • P69234-B21 HPE 1.92TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 CD8P SSD
  • P69237-B21 HPE 3.84TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 CD8P SSD
  • P69239-B21 HPE 7.68TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 CD8P SSD
  • P69546-B21 HPE 15.36TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 CD8P SSD
  • P85121-B21 HPE 1.92TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 SPDM 7600 SSD
  • P85124-B21 HPE 3.84TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 SPDM 7600 SSD
  • P85126-B21 HPE 7.68TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 SPDM 7600 SSD
  • P85128-B21 HPE 15.36TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 SPDM 7600 SSD
  • P87719-B21 HPE 1.92TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 Self-encrypting 7600 SSD
  • P87721-B21 HPE 3.84TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 Self-encrypting 7600 SSD
  • P87723-B21 HPE 7.68TB NVMe Gen5 Mainstream Performance Read Intensive E3S EC1 Self-encrypting 7600 SSD
  • P70392-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3S EC1 PS1010 SSD
  • P70395-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3S EC1 PS1010 SSD
  • P70397-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3S EC1 PS1010 SSD
  • P78789-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3.S EC1 PM1753 SSD
  • P78791-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3.S EC1 PM1753 SSD
  • P78793-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3.S EC1 PM1753 SSD
  • P91090-B21 HPE 1.92TB NVMe Gen5 Mainstream Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91092-B21 HPE 3.84TB NVMe Gen5 Mainstream Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91094-B21 HPE 7.68TB NVMe Gen5 Mainstream Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91096-B21 HPE 15.36TB NVMe Gen5 Mainstream Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91229-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91231-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P91233-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin Multi Vendor SSD
  • P85739-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85741-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85743-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85745-B21 HPE 30.72TB NVMe Gen5 High Performance Read Intensive E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P61191-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3S EC1 EDSFF SPDM CM7 SSD
  • P61195-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3S EC1 EDSFF SPDM CM7 SSD
  • P69241-B21 HPE 1.6TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 CD8P SSD
  • P69243-B21 HPE 3.2TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 CD8P SSD
  • P69245-B21 HPE 6.4TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 CD8P SSD
  • P70399-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3S EC1 PS1030 SSD
  • P70401-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3S EC1 PS1030 SSD
  • P70403-B21 HPE 12.8TB NVMe Gen5 High Performance Mixed Use E3S EC1 PS1030 SSD
  • P85114-B21 HPE 1.6TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 SPDM 7600 SSD
  • P85117-B21 HPE 3.2TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 SPDM 7600 SSD
  • P85119-B21 HPE 6.4TB NVMe Gen5 Mainstream Performance Mixed Use E3S EC1 SPDM 7600 SSD
  • P87715-B21 HPE 1.6TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 Self-encrypting 7600 SSD
  • P87717-B21 HPE 3.2TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 Self-encrypting 7600 SSD
  • P78784-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3.S EC1 PM1755 SSD
  • P91084-B21 HPE 1.6TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91086-B21 HPE 3.2TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91088-B21 HPE 6.4TB NVMe Gen5 Mainstream Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91098-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91100-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P91102-B21 HPE 12.8TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin Multi Vendor SSD
  • P78787-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3.S EC1 PM1755 SSD
  • P85731-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85733-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P85735-B21 HPE 12.8TB NVMe Gen5 High Performance Mixed Use E3.S EC1 E3 Thin PQC27 CM9 SSD
  • P63930-B21 HPE 3.84TB NVMe Gen4 Mainstream Performance Very Read Optimized E3S EC1 EDSFF P5430 SSD
  • P63934-B21 HPE 7.68TB NVMe Gen4 Mainstream Performance Very Read Optimized E3S EC1 EDSFF P5430 SSD
  • P63938-B21 HPE 15.36TB NVMe Gen4 Mainstream Performance Very Read Optimized E3S EC1 EDSFF P5430 SSD
  • P79065-B21 HPE 30.72TB NVMe Gen4 Mainstream Performance Very Read Optimized E3S EC1 EDSFF P5430 SSD
Ships same dayMost orders ship the same business day
1 to 5 year warrantyTested or factory sealed

All HPE ProLiant DL384 Gen12 Drives

Part number Capacity Interface Class Price Quantity and add
P63930-B21 HPE 3.84TB NVMe Gen4 Mainstream Performance Very Read Optimized E3S EC1 EDSFF P5430 SSD
Price on requestOut of stock
P57807-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM PM1743 SSD - Refurbished
¥1,051,657In stock
P57799-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM PM1743 SSD
¥512,949In stock
P61179-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM CM7 SSD
Price on requestOut of stock
P61183-B21 HPE 7.68TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM CM7 SSD
Price on requestOut of stock
P61187-B21 HPE 15.36TB NVMe Gen5 High Performance Read Intensive E3S EC1 EDSFF SPDM CM7 SSD
¥2,159,887In stock
P61191-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3S EC1 EDSFF SPDM CM7 SSD
Price on requestOut of stock
P61195-B21 HPE 6.4TB NVMe Gen5 High Performance Mixed Use E3S EC1 EDSFF SPDM CM7 SSD
¥754,570In stock
P63934-B21 HPE 7.68TB NVMe Gen4 Mainstream Performance Very Read Optimized E3S EC1 EDSFF P5430 SSD
¥821,098In stock
P63938-B21 HPE 15.36TB NVMe Gen4 Mainstream Performance Very Read Optimized E3S EC1 EDSFF P5430 SSD
Price on requestOut of stock
P70392-B21 HPE 3.84TB NVMe Gen5 High Performance Read Intensive E3S EC1 PS1010 SSD
Price on requestOut of stock
P70399-B21 HPE 3.2TB NVMe Gen5 High Performance Mixed Use E3S EC1 PS1030 SSD (HPE Spare #: P70493-001)
¥424,771In stock

Prices are today's store prices.

Ships same dayMost orders ship the same business day
1 to 5 year warrantyReplacement coverage on every part
5,000+ five-star reviewsShopper Approved, BBB A+ rating
Ships to 120+ countriesBy UPS; duties are collected by the carrier

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