HPE ProLiant DL380 Gen10 Processors

Genuine HPE-qualified Intel Xeon Scalable processors for the HPE ProLiant DL380 Gen10, new and refurbished, alongside heat sink kits. The platform spans two CPU generations — 1st Gen (Skylake, DDR4-2666) and 2nd Gen (Cascade Lake, DDR4-2933) — from 6-core Bronze parts to 28-core Platinums.

DL380 Gen10 Processor Specifications

• Families: 1st Gen Intel Xeon Scalable (Bronze 3104 through Platinum 8180/8180M) and 2nd Gen (through Platinum 8280/8280M/8280L), one or two sockets
• Range: 6 cores (Bronze 3104, 1.7GHz) up to 28 cores (Platinum 8180 and 8280 families, up to 2.7GHz base)
• Memory support: the CPU generation sets the platform's memory ceiling — DDR4-2666 on 1st Gen, DDR4-2933 on 2nd Gen; Optane Persistent Memory requires select 2nd Gen models
• Cooling: standard heat sinks plus the High Performance Heat Sink Kit and high-performance fan options for hot parts and demanding configurations

Both sockets must match. Buy processors in identical pairs, match your memory speed to the CPU generation (2933 MT/s needs 2nd Gen), and plan the High Performance Heat Sink Kit for high-TDP parts — heat sinks ship separately.

Which processors does the DL380 Gen10 support?

The refurb market makes formerly flagship silicon remarkably affordable here — 2nd Gen Gold parts hit the sweet spot of clocks, cores, and 2933 MT/s memory support. Two 28-core Platinums put 56 cores in 2U.

Choosing the Right DL380 Gen10 Processors

• Both processors must be identical — buy matched pairs, and match the existing CPU exactly when adding a second.
• Prefer 2nd Gen when you have the choice: same socket economics, DDR4-2933 support, and Optane PMem capability on select models.
• The CPU sets your memory speed — pair with the right DDR4 kits (2933 for 2nd Gen, 2666 for 1st).
• Check the heat sink: high-TDP parts and loaded configurations call for the High Performance Heat Sink Kit and matching fans.

Complete Your DL380 Gen10 Build

Every added processor unlocks 12 more DIMM slots: see DL380 Gen10 memory, then drives, storage controllers, networking, and power supplies, or the full DL380 Gen10 parts page. Neighboring generations: DL380 Gen10 Plus processors and DL380 Gen11 processors. Catalog-wide: HPE parts by server model.

DL380 Gen10 Processors FAQ

What processors does the HPE ProLiant DL380 Gen10 support?
1st Generation Intel Xeon Scalable (Bronze 3104 through Platinum 8180, up to 28 cores at DDR4-2666) and 2nd Generation (through Platinum 8280, 28 cores at DDR4-2933), in one- or two-socket configurations.

What is the maximum core count of the DL380 Gen10?
56 cores - two 28-core Platinum processors (8180-family on 1st Gen or 8280-family on 2nd Gen).

Can I upgrade a 1st Gen DL380 Gen10 to 2nd Gen processors?
The two generations share the platform, but firmware level and configuration rules apply - and both sockets must run the identical model. Verify your system ROM is current and match the target CPU against the QuickSpecs before ordering.

Do DL380 Gen10 processors come with heat sinks?
No - processor SKUs ship as the processor only. Standard heat sinks cover mainstream TDPs; high-TDP parts and demanding configurations need the High Performance Heat Sink Kit and matching fan options.

Which DL380 Gen10 processor is best for database licensing?
The low-core, higher-clock Gold models - they keep per-core license counts down while the 2nd Gen parts add DDR4-2933 support. The 28-core Platinums are for consolidation, not license efficiency.

Do both processors in a DL380 Gen10 need to match?
Yes - both sockets must carry the identical processor model. When adding a second CPU, order the exact model already installed.

✅ Looking for a specific DL380 Gen10 processor? Browse our full selection below.

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