HPE ProLiant DL380 Gen10 Plus Parts
The HPE ProLiant DL380 Gen10 Plus brings 3rd Generation Intel Xeon Scalable processors, DDR4-3200 memory, PCIe 4.0, and U.3 tri-mode storage to HPE's flagship 2U platform — the bridge between the DDR4 Gen10 era and the DDR5 Gen11 line. Every part below is genuine HPE, available new and refurbished, and tested for compatibility before it ships. Live pricing for each part number appears in the tables further down this page.
DL380 Gen10 Plus Platform at a Glance
- Processors: one or two 3rd Gen Intel Xeon Scalable CPUs (Ice Lake) — up to the 40-core Platinum 8380
- Memory: 32 DIMM slots (16 per processor), DDR4-3200 — up to 2TB of RDIMM or 8TB with 256GB LRDIMMs
- Storage: hot-plug SFF (U.2 NVMe, U.3 tri-mode, SAS/SATA) and LFF bays — up to 30 SFF or 20 LFF drives
- Expansion: PCIe 4.0 riser slots plus OCP 3.0 networking — no embedded network ports
- Power: one or two Flex Slot hot-plug PSUs, 800W–1600W Platinum and Titanium
- Management: HPE iLO 5 with Intelligent Provisioning
Gen10 Plus is its own platform. It takes 3rd Gen Xeon Scalable CPUs, DDR4-3200 memory, OCP 3.0 networking, and MR-series controllers — parts from the Gen10 (1st/2nd Gen CPUs, FlexibleLOM, Smart Array) are generally not interchangeable, so match parts to the exact generation.
Full platform detail is in the official HPE DL380 Gen10 Plus QuickSpecs.
Shop DL380 Gen10 Plus Parts by Category
- DL380 Gen10 Plus Memory — DDR4-3200 RDIMMs and LRDIMMs
- DL380 Gen10 Plus Drives — U.2/U.3 NVMe, SAS, and SATA in SFF and LFF
- DL380 Gen10 Plus Storage Controllers — MR416i and MR216i tri-mode controllers
- DL380 Gen10 Plus Networking Adapters — OCP 3.0 and PCIe, 1GbE to 25GbE and beyond
- DL380 Gen10 Plus Power Supplies — Flex Slot Platinum and Titanium PSUs
- DL380 Gen10 Plus Processors — 3rd Gen Xeon Scalable CPUs and heat sinks
Comparing generations? See DL380 Gen10 parts, DL380 Gen11 parts, our guide to how Gen10 and Gen11 compare, or browse all HPE parts by server model.
DL380 Gen10 Plus Parts FAQ
What is the difference between the DL380 Gen10 and DL380 Gen10 Plus?
The Gen10 Plus is a distinct platform, not a revision: 3rd Gen Intel Xeon Scalable processors (vs 1st/2nd Gen), 32 DIMM slots of DDR4-3200 (vs 24 slots at 2933), PCIe 4.0 (vs 3.0), OCP 3.0 networking (vs FlexibleLOM), and U.3 tri-mode drive bays. Parts are generally not interchangeable between the two - check each part's listing.
How much memory does the DL380 Gen10 Plus support?
32 DDR4-3200 DIMM slots (16 per processor): up to 2TB with 64GB RDIMMs or up to 8TB with 256GB LRDIMMs.
What drives does the DL380 Gen10 Plus accept?
Hot-plug SFF drives across U.2 NVMe, U.3 tri-mode, and SAS/SATA cage types, plus LFF configurations - up to 30 SFF or 20 LFF drives (12+4+4) with the optional mid-tray and rear cages.
Does the DL380 Gen10 Plus have built-in network ports?
No - the QuickSpecs list no standard network ports. Every build takes an OCP 3.0 networking card or a stand-up PCIe adapter.
Can I mix new and refurbished parts in the DL380 Gen10 Plus?
Yes. Genuine HPE parts perform identically whether new or refurbished, and our refurbished stock is tested before shipping - a popular way to expand this platform affordably.
✅ Looking for a specific DL380 Gen10 Plus part? Browse our full selection below.
Browse all models
Why Global One?
- Trusted by thousands. Over 36,000 customers in 100+ countries trust Global One Technology to deliver mission-critical HP Enterprise hardware - including Fortune 500 businesses, schools, hospitals, and federal, state, and local goverment agencies.
- HPE is our specialty! We only sell genuine HP Enterprise parts.
- EASY ordering process. Purchase online now with credit card or PayPal!
- FAST shipping. Global One Technology ships orders received by 4pm ET the same day and offers NEXT DAY delivery to US customers.
