HPE ProLiant DL380 Gen10 Plus Memory
Upgrade your HPE ProLiant DL380 Gen10 Plus with genuine HPE DDR4 Smart Memory, in stock new and refurbished and tested before shipping. The Gen10 Plus pairs 3rd Gen Intel Xeon Scalable processors with 32 slots of DDR4-3200 — a full 8-channel memory architecture per CPU.
DL380 Gen10 Plus Memory Specifications
- Memory type: HPE DDR4 Smart Memory — Registered (RDIMM) and Load Reduced (LRDIMM)
- Slots: 32 DIMM slots — 16 per processor, 8 channels per CPU, 2 DIMMs per channel
- Speed: DDR4-3200 — maximum speed is limited by the processor selection
- Maximum capacity: 2TB with RDIMMs (32 × 64GB) or 8TB with LRDIMMs (32 × 256GB)
- Population rule: select DIMMs in even quantities — odd counts unbalance the channels and can hurt performance
Pick one module type. The DL380 Gen10 Plus runs RDIMMs (to 2TB) or LRDIMMs (to 8TB) but not both together — and DIMMs must be installed in even quantities, or the memory channels run unbalanced.
How much memory can the DL380 Gen10 Plus hold?
| Configuration | Total capacity | Notes |
|---|---|---|
| 8 × 32GB RDIMM (2 CPUs) | 256GB | Entry build, one bank per processor |
| 16 × 32GB RDIMM (2 CPUs) | 512GB | Balanced 1 DIMM per channel |
| 32 × 32GB RDIMM (2 CPUs, all slots) | 1TB | The mainstream virtualization build |
| 32 × 64GB RDIMM (2 CPUs, all slots) | 2TB | RDIMM maximum |
| 32 × 256GB LRDIMM (2 CPUs, all slots) | 8TB | Platform maximum (LRDIMM) |
For most builds, 32GB and 64GB RDIMMs are the sweet spot — best cost per gigabyte on this platform's used/refurb market. LRDIMMs are the capacity play when a workload genuinely needs more than 2TB.
Choosing the Right DL380 Gen10 Plus Memory
- Don't mix RDIMMs and LRDIMMs — pick one module type for the whole server.
- Populate both processors identically and in even quantities per the QuickSpecs population rule.
- DDR4-3200 only: this platform takes DDR4 — the DDR5 kits from Gen11/Gen12 servers do not fit, and older 2666/2933 modules will clock the whole server down.
- Background reading: memory rank in HPE servers and why memory speed matters.
Complete Your DL380 Gen10 Plus Build
Pair memory with DL380 Gen10 Plus processors, drives, storage controllers, networking adapters, and power supplies, or start from the full DL380 Gen10 Plus parts page. Neighboring generations: DL380 Gen10 memory and DL380 Gen11 memory. Or browse parts by server model.
DL380 Gen10 Plus Memory FAQ
How much RAM does the HPE ProLiant DL380 Gen10 Plus support?
Up to 2TB with RDIMMs (32 x 64GB) or up to 8TB with LRDIMMs (32 x 256GB), across 32 DDR4-3200 slots - 16 per processor. With one processor, 16 slots are available.
What type of memory does the DL380 Gen10 Plus use?
HPE DDR4 Smart Memory at 3200 MT/s - both Registered (RDIMM) and Load Reduced (LRDIMM) types. DDR5 memory from Gen11/Gen12 servers is not compatible.
Can I mix RDIMMs and LRDIMMs in the DL380 Gen10 Plus?
No - choose one module type for the entire server. RDIMMs cover builds to 2TB at better cost per gigabyte; LRDIMMs are the path to 8TB.
Do DL380 Gen10 Plus DIMMs need to be installed in matched sets?
Yes, in practice - HPE's population rule calls for even DIMM quantities, and both processors should carry identical layouts. Odd quantities unbalance the memory channels and can reduce performance.
Can I use DL380 Gen10 memory in the DL380 Gen10 Plus?
Only if the exact part number appears in the Gen10 Plus QuickSpecs - the Gen10 runs DDR4 at up to 2933 MT/s while the Gen10 Plus lists 3200 MT/s modules, and slower DIMMs cap the entire server's memory speed. Match part numbers, not just capacities.
✅ Looking for a specific DL380 Gen10 Plus memory module? Browse our full selection below.
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