HPE ProLiant DL580 Gen12 Drives
Genuine HPE hot-plug drives for the HPE ProLiant DL580 Gen12, new and refurbished, tested before shipping. This 4U Intel Xeon 6 platform is SFF- and EDSFF-only: 2.5-inch U.3 bays on Basic Carriers plus E3.S NVMe bays, in configurations up to 32 drives.
DL580 Gen12 Drive Specifications
- Bay types: 2.5-inch SFF (U.3, Basic Carrier) and EDSFF E3.S — no 3.5-inch LFF bays on this model
- Maximums: up to 32 SFF, up to 32 EDSFF, or mixed 16 SFF + 16 EDSFF; plus an optional front 2SFF cage via the Universal Media Bay
- Interfaces: NVMe Gen4 and Gen5, SAS 12G and 24G, SATA 6G
- SSD endurance classes: Read Intensive (about 1 drive write per day), Mixed Use (about 3 DWPD), and Very Read Optimized
- HDDs: Mission Critical 10K SAS SFF drives for tiered or legacy workloads
- Carriers: Gen12 uses the Basic Carrier (BC) — Smart Carrier (SC) drives from Gen8–Gen10 servers do not fit
Check the carrier before you buy. DL580 Gen12 bays take Basic Carrier (BC) U.3 and EDSFF E3.S drives only — there are no 3.5-inch LFF bays, and Smart Carrier (SC) drives from Gen8–Gen10 servers do not fit.
What drives fit the DL580 Gen12?
| Bay type | Carrier / form factor | Interfaces | Max bays |
|---|---|---|---|
| 2.5-inch SFF | Basic Carrier, U.3 | NVMe Gen4/Gen5, SAS 12/24G, SATA 6G | 32 |
| EDSFF | E3.S EC1 | NVMe Gen5 (and Gen4 VRO) | 32 |
| Front 2SFF | Universal Media Bay, U.3 | NVMe/SAS/SATA | 2 |
Capacities run from 300GB 10K SAS HDDs to 15.36TB NVMe SSDs — a fully loaded EDSFF configuration exceeds 490TB of flash in 4U. E3.S is the forward-looking choice for all-NVMe builds; U.3 SFF keeps SAS, SATA, and NVMe options open in the same bays.
Choosing the Right DL580 Gen12 Drives
- Never mix interfaces, endurance classes, or drive types within one RAID array. Build arrays from identical drives.
- Match endurance to workload: Read Intensive for read-heavy data serving, Mixed Use for databases and write-heavy virtualization — our DWPD guide explains the classes.
- Boot from the NS204i-u module (dual-NVMe RAID1 boot device) instead of spending data bays on the OS.
- Check the carrier before reusing older drives: Smart Carrier drives from Gen10 and earlier are mechanically incompatible — see why HPE moved off Smart Carriers.
- Deciding between drive families? Start with how to choose the right HPE SSD.
Complete Your DL580 Gen12 Build
Drives pair with DL580 Gen12 storage controllers and the rest of the platform: memory, processors, networking, power supplies, or the full DL580 Gen12 parts page. On the previous generation? See DL580 Gen10 drives. Browse the wider catalog at all HPE server SSDs, EDSFF NVMe SSDs, U.3 SSDs, and parts by server model.
DL580 Gen12 Drives FAQ
Does the HPE ProLiant DL580 Gen12 support 3.5-inch LFF drives?
No. The DL580 Gen12 is SFF and EDSFF only: 2.5-inch U.3 bays and E3.S NVMe bays, up to 32 drives. If you need LFF capacity spindles, they'd live in external storage rather than this chassis.
What is the maximum storage capacity of the DL580 Gen12?
Over 490TB of NVMe flash internally, using 32 EDSFF bays with 15.36TB E3.S SSDs. U.3 SFF configurations reach similar totals with 15.36TB 2.5-inch NVMe or SAS SSDs.
Can I use drives from a Gen9 or Gen10 ProLiant in the DL580 Gen12?
No - those generations use the Smart Carrier (SC) tray, while Gen12 bays take Basic Carrier (BC) and EDSFF drives. The carriers are not interchangeable, so drives must be sourced in the correct Gen12 carrier.
Are HPE Multi Vendor SSDs genuine HPE drives?
Yes. Multi Vendor (MV) SSDs are HPE-qualified, HPE-firmware drives sourced from multiple flash manufacturers to improve availability and price. They carry HPE part numbers and full compatibility with the DL580 Gen12.
What's the difference between Read Intensive and Mixed Use SSDs?
Endurance. Read Intensive drives are rated around 1 drive write per day and cost less per TB; Mixed Use drives are rated around 3 DWPD for write-heavy databases and virtualization. Match the class to your write workload and never mix classes in one array.
Do DL580 Gen12 NVMe drives require a RAID controller?
Not necessarily. NVMe drives can run direct-attached for maximum performance with software or VROC RAID, or connect through a tri-mode MR controller (like the MR416i or MR932i-p) when you want hardware RAID across NVMe, SAS, or SATA.
✅ Looking for a specific DL580 Gen12 drive? Browse our full selection above, or contact our HPE specialists for a guaranteed-compatible recommendation.
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