HPE ProLiant DL380 Gen12 Parts
The HPE ProLiant Compute DL380 Gen12 brings Intel Xeon 6 processors, DDR5-6400 memory, and PCIe 5.0 I/O to HPE's best-selling 2U server line, with chassis options from 8 LFF spindles to 36 EDSFF flash drives. Every part below is genuine HPE, available new and refurbished, and tested for compatibility before it ships. Live pricing for each part number appears in the tables further down this page.
DL380 Gen12 Platform at a Glance
- Processors: one or two Intel Xeon 6 CPUs — Efficient-core (E-core) models up to 144 cores, or Performance-core (P-core) models up to 86 cores
- Memory: 32 DIMM slots (16 per processor), DDR5-6400 ECC RDIMM — up to 8TB with 256GB 3DS kits
- Storage: hot-plug SFF (U.3), LFF, and EDSFF E3.S bays by chassis — up to 30 SFF, 20 LFF, or 36 EDSFF drives (over 1PB of NVMe flash)
- Expansion: up to 8 PCIe 5.0 slots plus OCP 3.0 slots A (standard) and B (optional)
- Power: one or two Flex Slot hot-plug power supplies, 800W–2200W, Platinum and Titanium
- Management: HPE iLO 7 with Intelligent Provisioning; TPM 2.0 embedded
Know your chassis before you order. The DL380 Gen12 ships in SFF, 24SFF, 8LFF, 12LFF, and EDSFF CTO configurations — the chassis determines which drive bays, cages, and fan kits fit, so match parts to the configuration you actually have.
Full platform detail is in the official HPE DL380 Gen12 QuickSpecs.
Shop DL380 Gen12 Parts by Category
- DL380 Gen12 Memory — DDR5-6400 RDIMMs from 16GB to 256GB
- DL380 Gen12 Drives — NVMe, SAS, and SATA SSDs plus HDDs in SFF, LFF, and EDSFF
- DL380 Gen12 Storage Controllers — MR-series RAID, the Gen5 MR932i-p, HBAs, and boot devices
- DL380 Gen12 Networking Adapters — 1GbE to 100GbE and InfiniBand, PCIe and OCP 3.0
- DL380 Gen12 Power Supplies — Flex Slot Platinum and Titanium hot-plug PSUs
- DL380 Gen12 Processors — Intel Xeon 6 E-core and P-core CPUs plus heat sinks
Moving between generations? See DL380 Gen11 parts, our guide to the DL380 line's history, or browse all HPE parts by server model.
DL380 Gen12 Parts FAQ
What is the HPE ProLiant DL380 Gen12 used for?
It's HPE's mainstream 2U dual-socket platform - the generation that pairs Intel Xeon 6 processors with DDR5-6400 memory and PCIe 5.0. Typical roles are virtualization, databases, and general enterprise workloads, with chassis options spanning LFF capacity builds to 36-bay EDSFF all-flash.
How much memory does the DL380 Gen12 support?
Up to 8TB of DDR5: 32 DIMM slots (16 per processor) with modules from 16GB to 256GB 3DS RDIMMs at up to 6400 MT/s.
What drives does the DL380 Gen12 accept?
Hot-plug SFF U.3 drives on Basic Carriers, LFF SAS/SATA drives, and EDSFF E3.S NVMe - up to 30 SFF, 20 LFF, or 36 EDSFF bays depending on the chassis configuration. NVMe, SAS, and SATA interfaces are all supported.
Does the DL380 Gen12 have built-in network ports?
No - aside from the dedicated iLO management port, there is no embedded production networking. Every configuration needs at least one OCP 3.0 or PCIe network adapter.
Can I mix new and refurbished parts in the DL380 Gen12?
Yes. Genuine HPE parts perform identically whether new or refurbished, and our refurbished stock is tested before shipping - a common way to add memory, drives, or a redundant power supply at lower cost.
✅ Looking for a specific DL380 Gen12 part? Browse our full selection below.
Browse all models
Why Global One?
- Trusted by thousands. Over 36,000 customers in 100+ countries trust Global One Technology to deliver mission-critical HP Enterprise hardware - including Fortune 500 businesses, schools, hospitals, and federal, state, and local goverment agencies.
- HPE is our specialty! We only sell genuine HP Enterprise parts.
- EASY ordering process. Purchase online now with credit card or PayPal!
- FAST shipping. Global One Technology ships orders received by 4pm ET the same day and offers NEXT DAY delivery to US customers.
