HPE ProLiant DL380 Gen11 Memory
The DL380 Gen11 has 32 DIMM slots, 16 per processor, and takes HPE DDR5 EC8 registered memory (RDIMMs). Which kit you need depends on the processor: 4th Gen Intel Xeon Scalable processors use DDR5-4800 kits; 5th Gen processors use DDR5-5600 kits. Either way the server supports up to 8TB with two processors and 256GB in every slot (4TB per processor; 32 DIMMs with the 8SFF or 16SFF chassis, 16 with the 24SFF).
- 32 DIMM slots, 16 per processor
- DDR5 EC8 RDIMM, 16GB to 256GB
- Up to 8TB
- 8 channels per processor
Specifications match the HPE ProLiant DL380 Gen11 QuickSpecs. LRDIMM, UDIMM, non-ECC and DDR4 are not supported.
How processor, kit and speed fit together
Each processor has 8 memory channels with 2 slots per channel. One DIMM in every channel runs the kit at its full rating; filling the second slot doubles capacity and steps the speed down.
| Processor | Kit to buy | One DIMM per channel | Two DIMMs per channel |
|---|---|---|---|
| 5th Gen Intel Xeon Scalable (Silver 45xx, Gold 55xx / 65xx, Platinum 85xx) | DDR5-5600 | 5600 MT/s | Not stated in the QuickSpecs |
| 4th Gen Intel Xeon Scalable (Silver 44xx, Gold 54xx / 64xx, Platinum 84xx) | DDR5-4800 | 4800 MT/s | 4400 MT/s |
Silver and some Gold processors are rated below the kit speed and run the memory at their own rating. The speed the server delivers is the lowest of the processor rating, the population and the slowest installed DIMM. HPE qualifies 1, 2, 4, 6, 8, 12 or 16 DIMMs per processor; the picker uses those counts.
Three rules that avoid a return
1 Match the kit to the processor
DDR5-5600 kits are listed for 5th Gen processors and DDR5-4800 kits for 4th Gen. If you are adding to memory that is already installed, match the part number on the existing DIMM label and you cannot go wrong.
2 Do not mix x4 and x8, or 3DS and non-3DS
HPE does not support mixing x4 and x8 DIMMs, or 3DS with non-3DS DIMMs, and the 96GB kit cannot be mixed with any other capacity. Keep every DIMM in a bank the same, and populate both processors identically in even quantities.
3 Buy -B21, not -F21
Both suffixes describe the same module, but -F21 is sold only inside a factory-built server. The -B21 kits on this page are the ones you can buy and install yourself.
DL380 Gen11 memory questions
How much memory does the HPE ProLiant DL380 Gen11 support?
Up to 8TB with two processors: 32 slots with 256GB DDR5 RDIMMs in every one, and up to 4TB per processor. HPE notes that 32 DIMMs fit the 8SFF and 16SFF chassis; the 24SFF chassis takes 16. With a single processor only its 16 slots are usable.
What type of memory does the DL380 Gen11 use?
HPE DDR5 EC8 registered DIMMs (RDIMMs): DDR5-4800 kits with 4th Gen Intel Xeon Scalable processors and DDR5-5600 kits with 5th Gen, in 16GB to 256GB capacities. LRDIMM, UDIMM, non-ECC and DDR4 memory are not supported.
Can I use DDR5-4800 kits with a 5th Gen processor?
Buy the family HPE lists for your processor generation, and never mix the two families in one server. If the server already has memory installed, add the same part number.
What speed will the memory run at?
5600 MT/s (DDR5-5600 kits) or 4800 MT/s (DDR5-4800 kits) with one DIMM per channel, up to 8 per processor. With both slots of a channel filled, DDR5-4800 kits run at 4400 MT/s; HPE does not publish the figure for the DDR5-5600 kits. Processors rated below the kit speed run the memory at their own rating.
Are there special rules for the 96GB and 256GB kits?
Yes. The 96GB kit cannot be mixed with any other capacity, and HPE requires the High-performance Fan Kit when 96GB or larger DIMMs are installed. Check the server's current population against these rules before ordering 96GB or 256GB DIMMs for a server that is already built.
Is this genuine HPE memory, and what is the warranty?
Yes. Every kit is a genuine HPE part, tested or factory sealed, and covered by our 5-year memory warranty. Most orders ship the same business day.
All HPE ProLiant DL380 Gen11 Memory kits
| Part number | Capacity | Type | Speed | Price | Availability | Add to cart |
|---|---|---|---|---|---|---|
 P43328-B21P43328-B21 HPE 32GB Dual Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory for Gen11 servers |
$1,895.00 | In stock | ||||
 P43322-B21P43322-B21 HPE 16GB Single Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory for Gen11 servers |
$995.00 | In stock | ||||
 P64706-B21P64706-B21 HPE 32GB (1x32GB) Dual Rank x8 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit |
$1,946.00 | In stock | ||||
 P43331-B21P43331-B21 HPE 64GB Dual Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory for Gen11 servers |
$3,768.00 | In stock | ||||
P07818-B21P07818-B21 HPE DDR4 DIMM Blank Kit |
$189.00 | In stock | ||||
 P43325-B21P43325-B21 HPE 32GB 1Rx4 PC5-4800B-R Smart Memory for Gen11 servers |
Price on request | Out of stock | ||||
 P43334-B21P43334-B21 HPE 128GB Quad Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory for Gen11 servers |
$6,455.00 | In stock | ||||
 P43337-B21P43337-B21 HPE 256GB Octal Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory for Gen11 servers |
$14,259.00 | In stock | ||||
 P64705-B21P64705-B21 HPE 16GB (1x16GB) Single Rank x8 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit |
$1,449.00 | In stock | ||||
 P64707-B21P64707-B21 HPE 64GB (1x64GB) Dual Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit |
$3,895.00 | In stock | ||||
 P64708-B21P64708-B21 HPE 96GB (1x96GB) Dual Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory Kit |
$5,798.00 | In stock | ||||
 P64709-B21P64709-B21 HPE 128GB (1x128GB) Quad Rank x4 DDR5-5600 CAS-52-45-45 EC8 Registered 3DS Smart Memory Kit |
$8,225.00 | In stock | ||||
 P66675-B21P66675-B21 HPE 96GB Dual Rank x4 DDR5-4800 CAS-46-45-45 EC8 Registered Smart Memory for Gen11 servers |
Price on request | Out of stock | ||||
 P69974-B21P69974-B21 HPE 128GB Dual Rank x4 DDR5-4800 CAS-46-45-45 EC8 Registered Smart Memory for Gen11 servers |
$6,996.00 | In stock | ||||
 P69976-B21P69976-B21 HPE 128GB Dual Rank x4 DDR5-5600 CAS-46-45-45 EC8 Registered Smart Memory for Gen11 servers |
$6,255.00 | In stock |
Prices shown are today's store prices. Volume pricing is available on every kit; ask for a quote for ten or more.
Buying for several servers, or a different model?
Send us the server models and the memory you want in each and we will quote every kit by the next business day. Live chat is the fastest way to reach us.
