HPE ProLiant Server Memory
Shop new, genuine HPE server memory for every ProLiant generation, from Gen8 through the latest Gen12 platforms. Whether you're expanding capacity for virtualization, accelerating mission-critical databases, or upgrading older systems, we stock factory-original HPE ProLiant memory kits — DDR3, DDR4, and DDR5 — for nearly every HPE ProLiant model, including the DL360, DL380, DL385, ML350, and more.
We've supplied genuine HPE parts to IT professionals since 2003, serving more than 36,000 customers in over 120 countries. In-stock HPE memory ordered by 5pm ships the same day, with next-day delivery available across the US — so your upgrade or replacement is installed when you need it, not weeks later.
Start by selecting your server generation:
- HPE Gen12 Server Memory
- HPE Gen11 Server Memory
- HPE Gen10 Plus Server Memory
- HPE Gen10 Memory (1st Gen CPU)
- HPE Gen10 Memory (2nd Gen CPU)
- HPE Gen9 Server Memory
- HPE Gen8 Server Memory
How to Choose the Right HPE ProLiant Memory
The correct HPE memory for your server is determined by its generation and, in some cases, its processor. Gen8 servers use DDR3 memory, while Gen9 servers moved to DDR4. Gen10 servers also use DDR4, but the supported speed depends on the CPU installed: servers with 1st Gen Intel Xeon Scalable processors support DDR4-2666, while servers with 2nd Gen Intel Xeon Scalable processors support DDR4-2933 — which is why we separate Gen10 memory into two categories above. Gen10 Plus servers step up to DDR4-3200, and the newest Gen11 and Gen12 ProLiant servers use DDR5 memory. If you're unsure which processor your Gen10 server has, the CPU model number on your original order or in iLO will tell you.
RDIMM vs. LRDIMM
Most HPE ProLiant configurations use Registered DIMMs (RDIMMs), which balance capacity, speed, and cost for the widest range of workloads. Load Reduced DIMMs (LRDIMMs) buffer the data lines as well as the command lines, allowing higher total memory capacities in servers running large in-memory databases or dense virtualization. RDIMMs and LRDIMMs cannot be mixed in the same server, so match the type already installed when adding memory to an existing system.
Why Genuine HPE Smart Memory Matters
Every module we sell is new, genuine HPE memory — not third-party compatible RAM. Genuine HPE Smart Memory is authenticated and qualified by HPE for ProLiant servers, and it unlocks HPE-exclusive features such as advanced memory error detection and memory health reporting through iLO. That means fewer compatibility surprises, full performance at the rated speed, and no risk of support complications from unqualified modules.
Understanding HPE Memory Part Numbers
You'll often see the same HPE memory kit listed under several part-number suffixes — for example, P00924-B21, P00924-K21, and P00924-H21. These suffixes indicate different HPE ordering and packaging channels for the same physical module, so any of them will function identically in a compatible server. If you're searching for a specific part number, matching the base number is what matters.
HPE Server Memory FAQs
What memory does the HPE ProLiant DL380 Gen10 use?
The DL380 Gen10 (like the DL360 Gen10) uses DDR4 Registered Smart Memory. Servers configured with 1st Gen Intel Xeon Scalable processors support DDR4-2666 memory, while those with 2nd Gen Intel Xeon Scalable processors support DDR4-2933 memory.
Is the memory you sell new and genuine HPE?
Yes. Every memory kit in this category is new, factory-original genuine HPE memory. We do not sell third-party or compatible-brand modules.
Can I mix RDIMM and LRDIMM memory in the same server?
No. HPE ProLiant servers do not support mixing Registered DIMMs and Load Reduced DIMMs. All installed modules must be the same type, and for best performance HPE recommends populating channels with matching kits.
Do HPE Gen11 and Gen12 servers use DDR4 memory?
No. Gen11 and Gen12 ProLiant servers use DDR5 memory exclusively. DDR4 and DDR5 modules are not interchangeable — they are keyed differently and will not fit in the same slots.
How do I find the right HPE memory for my server?
Select your server generation from the list above to see every compatible kit, or contact our team with your server model or an existing memory part number and we'll confirm compatibility before you order.
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P43334-B21 HPE 32GB Dual Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory for Gen11 servers
PN: P43334-B21
Price: $15,165.00Today's Price: $8,859.00Qty In Stock: 55 -
P43337-B21 HPE 256GB Octal Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory for Gen11 servers
PN: P43337-B21
Out of Stock -
P43789-B21 HPE DX 32GB (1 x 32GB) Single Rank x4 DDR4-3200 CAS-22-22-22 Registered Smart FIO Memory Kit
PN: P43789-B21
Price: $2,425.00Today's Price: $1,485.00Qty In Stock: 6 -
P45867-B21 HPE Synergy 256GB (1 x 256GB) Octal Rank x4 DDR4-3200 CAS-26-22-22 Load Reduced 3DS Smart Memory Kit
PN: P45867-B21
Out of Stock -
P50309-B21 HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory
PN: P50309-B21
Price: $1,035.00Today's Price: $859.00Qty In Stock: 22 -
P50310-B21 HPE 32GB (1x32GB) Single Rank x4 DDR5-4800 CAS-40-39-39 EC8 Registered Smart Memory
PN: P50310-B21
Price: $1,825.00Today's Price: $1,348.00Qty In Stock: 3 -
P50313-B21 HPE 128GB (1x128GB) Quad Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory
PN: P50313-B21
Price: $7,349.00Today's Price: $4,985.00Qty In Stock: 7 -
P50314-B21 HPE 256GB (1x256GB) Octal Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory
PN: P50314-B21
Out of Stock -
P63345-B21 HPE 128GB (1x128GB) Quad Rank x4 DDR5-4800 CAS-46-39-39 EC8 Registered 3DS Smart Memory Kit
PN: P63345-B21
Price: $6,495.00Today's Price: $3,850.00Qty In Stock: 1 -
P66675-B21 HPE 96GB Dual Rank x4 DDR5-4800 CAS-46-45-45 EC8 Registered Smart Memory for Gen11 servers
PN: P66675-B21
Out of Stock -
P69726-B21 HPE 16GB (1x16GB) Single Rank x8 DDR5-6400 CAS-46-45-45 EC8 Registered Smart Memory Kit
PN: P69726-B21
Price: $2,525.00Today's Price: $1,985.00Qty In Stock: 3 -
P69728-B21 HPE 64GB (1x64GB) Dual Rank x4 DDR5-6400 CAS-46-45-45 EC8 Registered Smart Memory Kit
PN: P69728-B21
Price: $5,925.00Today's Price: $3,795.00Qty In Stock: 100


