Looking for more HPE Server HDD options?
Browse our extensive selection of HPE Server HDD to find the perfect fit for your needs.
857646-B21
857646-B21 HPE 10TB SAS 12G Midline 7.2K LFF (3.5in) LP Helium 512e Digitally Signed Firmware HDD
- SKU:
- 857646-B21
- Condition:
- New If factory sealed packaging is required, please request a quote below and enter your special request in the 'Add Notes' section.
- Warranty:
- 1 Year

- Collection:
- HPE Server HDD
- Collection URL:
- /hpe-server-hot-plug-hdd.htm
This item, 857646-B21, is the HPE option part number for the product described as 10TB SAS 12G Midline 7.2K LFF (3.5in) LP Helium 512e Digitally Signed Firmware HDD. Further details below.
This 10TB hot-swap hard drive combines high capacity with robust SAS performance. Featuring a 3.5" LFF low profile form factor and a fast 12Gb/s SAS interface, this drive is built for demanding server environments. Helium technology increases reliability and reduces power consumption.
This item is equipped with digitally signed firmware for enhanced security. The 512e advanced format ensures compatibility with modern systems. Designed for HPE ML110 Gen10 servers, compatibility includes but may not be limited to this model, making it ideal for applications requiring both capacity and speed.
HPE Option Part #: 857646-B21
HPE Spare Part #: 857966-001
PRODUCT SPECIFICATIONS FOR 857646-B21:
- Device Type: Hard drive - hot-swap
- Capacity: 10 TB
- Form Factor: 3.5" LFF Low Profile
- Interface: SAS 12Gb/s
- Features: Advanced format 512e
- Drive Transfer Rate: 1.2 GBps (external)
- Spindle Speed: 7200 rpm
- Interfaces: 1 x SAS 12 Gb/s
- Compatible Bay: 3.5" LFF Low Profile
COMPATIBLE WITH:
PROLIANT ML SERIES
** This list may not be complete. Contact us via Live Chat if you have any questions about compatibility.
HPE PARTSURFER INFO FOR 857646-B21
Spare PN | Description | |
---|---|---|
857966-001 | 10TB SAS hard drive - 6Gb/s interface, 7,200 RPM, 3.5-inch large form factor (LFF), low profile (LP) |
Last updated: 5/2/2025
- Trusted by thousands. Over 36,000 customers in 100+ countries trust Global One Technology to deliver mission-critical HP Enterprise hardware - including Fortune 500 businesses, schools, hospitals, and federal, state, and local goverment agencies.
- HPE is our specialty! We only sell genuine HP Enterprise parts.
- EASY ordering process. Purchase online now with credit card or PayPal!
- FAST shipping. Global One Technology ships orders received by 5pm the same day and offers NEXT DAY delivery to US customers.
This product is warrantied against hardware failure for a period of 1 Year from the date of purchase. Before making a purchase, please take a moment to review our return policy below.
Returns
It is the customer's responsibility to verify compatibility with their machine(s) before placing an order. If an item is ordered by mistake, it can be returned for refund, minus a 25% restocking fee, within 5 business days of receipt. The cost of freight is not refundable.
Please be aware that factory-sealed equipment can only be returned if it remains unopened.
Defective Products
If you have received a defective part and your machine is still within the HPE warranty period, please initiate a warranty exchange by visiting the HPE Enterprise Support Center. Be sure to have the serial numbers of the defective drive and your server/storage array handy.
In case your hardware becomes defective during the Global One warranty period, but the HPE warranty has expired, you can return the product to us for a working replacement. You are responsible for the shipment of returned merchandise. However, we will cover the expense of Ground /Economy shipment for the replacement item(s).
Requesting an RMA
To initiate a return or warranty claim, please complete and submit the RMA Request Form.